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在“Elsevier电子期刊”中，命中：659条，耗时：0.0139949 秒

在所有数据库中总计命中：2,241条

1.Phosphoinositide 3-kinase γ ties chemoattractant- and adrenergic control of microglial motility

作者：Nadine Schneble^a ; ^{Nadine.Schneble@med.uni-jena.de} ; Caroline Schmidt^a ; ^{Caroline.Schmidt@med.uni-jena.de} ; Reinhard Bauer^a ; ^{Reinhard.Bauer@med.uni-jena.de} ; Jö ; rg P. Mü ; ller^a ; ^{Joerg.Mueller2@med.uni-jena.de} ; Shamci Monajembashi^b ; ^{shamci@fli-leibniz.de} ; Reinhard Wetzker^a ; ^{Reinhard.Wetzker@uni-jena.de}

关键词：Akt ; protein kinase Akt/PKB ; ATP ; Adenosine triphosphate ; C5a ; complement system component 5a ; C5aR ; complement system component 5a receptor ; cAMP ; Cyclic adenosine monophosphate ; DAPI ; 4&prime ; 6-diamidino-2-phenylindole ; HRP ; horseradish peroxidase ; PIP3 ; phosphatidylinositol (34 ; 5)-trisphosphate ; shRNA ; small hairpin RNA

刊名：Molecular and Cellular Neuroscience

出版年：2017

2.Class I phosphatidylinositol 3-kinase inhibitors for cancer therapy

作者：Wennan Zhao^&dagger ; ; Yuling Qiu^&dagger ; ; Dexin Kong ; ^{kongdexin@tmu.edu.cn}

关键词：Phosphatidylinositol 3-kinase ; PI3K inhibitor ; Drug candidate ; Cancer therapy ; PI3K/mTOR selectivity ; Anticancer

刊名：Acta Pharmaceutica Sinica B

出版年：2017

3.Regulation of proteasome activity by P2Y₂ receptor underlies the neuroprotective effects of extracellular nucleotides

作者：Laura de Diego-Garcí ; a^a ; ^c ; Mercedes Ramí ; rez-Escudero^a ; Á ; lvaro Sebastiá ; n-Serrano^a ; ^c ; Juan Ignacio Diaz-Herná ; ndez^a ; ^d ; Jesú ; s Pintor^b ; José ; J. Lucas^d ; ^e ; Miguel Dí ; az-Herná ; ndez^a ; ^c ; ^{migueldiaz@ucm.es}

关键词：UPS ; Ubiquitin-Proteasome System ; P2Y2R ; P2Y2 receptor ; IP3 ; inositol 14 ; 5-trisphosphate ; MEK1/2 ; MAP kinase kinases ; ERK ; extracellular signal-regulated kinase ; PKC ; protein kinase C ; PKA ; protein kinase A ; PI3K ; inositol 14 ; 5-trisphosphate 3-kinases ; MAPK/ERK ; mitogen-activated protein kinases ; GFP ; green fluorescent protein ; YFP ; yellow fluorescent protein ; ATP ; adenosine triphosphate ; UTP ; uridine triphosphate ; PPADS ; pyridoxalphosphate-6-azophenyl-2&prime ; 4&prime ; -disulfonic acid ; Up4U

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

4.Elevated levels of alpha-synuclein blunt cellular signal transduction downstream of Gq protein-coupled receptors

作者：Mattia Volta ; ^{mattia.volta@eurac.edu} ; Alexandros A. Lavdas ; Julia Obergasteiger ; Christa Ü ; berbacher ; Anne Picard ; Peter P. Pramstaller ; Andrew A. Hicks ; Corrado Corti ; ^{corrado.corti@eurac.edu}

关键词：aSyn ; Alpha-synuclein ; PD ; Parkinson's disease ; PLCβ1 ; phospholipase Cβ1 ; PI(4 ; 5)P2 ; phosphoinositide-4 ; 5-bisphosphate ; Gq-PCRs ; Gq protein-coupled receptors ; IP3 ; inositol-14 ; 5-trisphosphate ; DAG ; diacylglycerol ; PKC ; protein kinase C ; MAPKs ; mitogen-activated protein kinase ; WT ; wild-type ; ERK1/2 ; extracellular-signal regulated kinase 1/2 ; 5-HT ; serotonin ; (CHO) ; Chinese hamster ovary cells ; FBS ; fetal bovine serum ; AP-1 ; activator protein-1 ; RT ; room temperature ; 5-HT ; serotonin ; SERCA ; sarc

刊名：Cellular Signalling

出版年：2017

5.PI(3,4,5)P₃ Engagement Restricts Akt Activity to Cellular Membranes

作者：Michael Ebner¹ ; ³ ; Iva Lučić¹ ; ³ ; Thomas A. Leonard¹ ; ² ; ^{thomas.leonard@mfpl.ac.at} ; Ivan Yudushkin¹ ; ² ; ⁴ ; ^{ivan.yudushkin@mfpl.ac.at}

关键词：protein kinase B/Akt ; AGC kinases ; allostery ; cellular signaling ; signal transduction ; fluorescence correlation spectroscopy ; fluorescence cross-correlation spectroscopy ; cellular membranes ; phosphatidylinositol-34 ; 5-trisphosphate ; protein phosphatases

刊名：Molecular Cell

出版年：2017

6.Intradialytic creatine supplementation: A scientific rationale for improving the health and quality of life of dialysis patients

作者：Theo Wallimann^a ; ^{theo.wallimann@cell.biol.ethz.ch} ; Uwe Riek^a ; Michael Mö ; ddel^b

关键词：AGAT ; arginine-glycine amidinotransferase (mostly in the kidney) ; AMPK ; AMP-activated protein kinase ; ANT ; mitochondrial adenine nucleotide or ATP/ADP carrier of the inner mitochondrial membrane ; ATP ; adenosine-trisphosphate ; the universal energy currency of living systems ; CK ; creatine kinase ; MM-CK ; cytosolic muscle-type MM-CK dimer ; cytosolic non-muscle or brain-type BB-CK dimer ; mtCK octameric mitochondrial CK ; CKD patients ; chronic kidney dialysis patients ; CKD ; chronic kidney disease patie

刊名：Medical Hypotheses

出版年：2017

7.Targeting calcium signaling in cancer therapy

作者：Chaochu Cui^a ; ^b ; Robert Merritt^b ; ^c ; Liwu Fu^a ; Zui Pan^b ; ^c ; ^d ; ^{zui.pan@uta.edu}

关键词：20-GPPD ; 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol ; CaM ; calmodulin ; CaMKII ; calmodulin-dependent protein kinase II ; CBD ; cannabidiol ; CBG ; cannabigerol ; CPZ ; capsazepine ; CRAC ; Ca2+ release-activated Ca2+ channel ; CTL ; cytotoxic T cells ; CYP3A4 ; cytochrome P450 3A4 ; ER/SR ; endoplasmic/sarcoplasmic reticulum ; HCX ; H+/Ca2+ exchangers ; IP3 ; inositol 14 ; 5-trisphosphate ; IP3R (1 ; 2 ; 3) ; IP3 receptor (type 1 ; type 2 ; type 3) ; mAb ; monoclonal antibody ; MCU ; mitochondrial Ca2+ uniporter ; MCUR1 ; MC

刊名：Acta Pharmaceutica Sinica B

出版年：2017

8.Specific expression and function of inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) in wild type and knock-out mice

作者：Ariane Scoumanne^a ; ¹ ; Patricia Molina-Ortiz^a ; Daniel Monteyne^b ; David Perez-Morga^b ; ^c ; Christophe Erneux^d ; Sté ; phane Schurmans^a ; ^{sschurmans@ulg.ac.be" class="auth_mail" title="E-mail the corresponding author}

关键词：Inositol 134 ; 5-tetrakisphosphate ; Inositol 14 ; 5-trisphosphate 3-kinase ; Itpkc ; Tissue expression ; Mouse

刊名：Advances in Biological Regulation

出版年：2016

9.Ibrutinib inhibition of Bruton protein-tyrosine kinase (BTK) in the treatment of B cell neoplasms

作者：Robert Roskoski Jr. ^{rrj@brimr.org" class="auth_mail" title="E-mail the corresponding author}

关键词：AS ; activation segment ; CLL ; chronic lymphocytic leukemia ; CS or C-spine ; catalytic spine ; CL ; catalytic loop ; HΦ or Φ ; hydrophobic ; IP3 ; inositol 14 ; 5 trisphosphate ; IP6 ; inositol 12345 ; 6 hexakisphosphate ; MCL ; mantle cell lymphoma ; MW ; molecular weight ; NSCLC ; non-small cell lung cancer ; PKA ; protein kinase A ; PIP2 ; phosphatidyl inositol 4 ; 5 bisphosphate ; PIP3 ; phosphatidyl inositol 34 ; 5 trisphosphate ; RA ; rheumatoid arthritis ; RS or R-spine ; regulatory spine ; Sh1 ; shell residue 1 ; WM ; W

刊名：Pharmacological Research

出版年：2016

10.Differential role of SNAP-25 phosphorylation by protein kinases A and C in the regulation of SNARE complex formation and exocytosis in PC12 cells

作者：Jing Gao^a ; Makiko Hirata^a ; ^b ; Akiko Mizokami^a ; Jin Zhao^a ; Ichiro Takahashi^b ; Hiroshi Takeuchi^c ; Masato Hirata^a ; ^{hirata1@dent.kyushu-u.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：CSP ; cysteine string protein ; FSK ; forskolin ; GST ; glutathione S-transferase ; Ins(14 ; 5)P3 ; d-myo-inositol 14 ; 5-trisphosphate ; KO ; knock out ; NA ; noradrenalin ; NSF ; N-ethylmaleimide-sensitive factor ; PKA ; cAMP-dependent protein kinase ; PKC ; protein kinase C ; PMA ; phorbol 12-myristate 13-acetate ; SDS ; sodium dodecyl sulfate ; SNAP-25 ; synaptosomal-associated protein of 25 ; kDa ; SNARE ; soluble NSF-attachment protein receptors ; VAMP ; vesicle-associated membrane protein ; WT ; wild type

刊名：Cellular Signalling

出版年：2016

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