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在“
Elsevier电子期刊
”中,
命中:
303,807
条,耗时:0.0159588 秒
在所有数据库中总计命中:
4,409,154
条
1.
C0818, a novel curcumin derivative, interacts with Hsp
90
and inhibits Hsp
90
ATPase activity
作者:
Yingjuan Fan
a
;
b
;
Yang Liu
a
;
b
;
Lianru Zhang
c
;
Fang Cai
a
;
b
;
Liping Zhu
a
;
b
;
Jianhua Xu
a
;
b
;
xjh@mail.fjmu.edu.cn
关键词:
Curcumin derivative
;
Hsp
90
;
ATPase activity
;
Fluorescence spectrometry
;
Interaction
刊名:Acta Pharmaceutica Sinica B
出版年:2017
2.
Virtual screening and biophysical studies lead to HSP
90
inhibitors
作者:
Renjie Huang
;
Daniel M. Ayine-Tora
;
M. Nasri Muhammad Rosdi
;
Yu Li
;
Jó
;
hannes Reynisson
;
j.reynisson@auckland.ac.nz
;
Ivanhoe K.H. Leung
;
i.leung@auckland.ac.nz
关键词:
17-AAG
;
17-allylamino-17-demethoxygeldanamycin
;
17-DMAG
;
17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG)
;
ADP
;
adenosine diphosphate
;
AMPPCP
;
5&prime
;
-adenylylmethylenediphosphonate
;
ASP
;
Astex statistical potential
;
ATP
;
adenosine triphosphate
;
CS
;
ChemScore
;
GS
;
GoldScore
;
HB
;
hydrogen bonding
;
HSP
90
;
heat shock protein
90
;
HSQC
;
heteronuclear single quantum correlation
;
KD
;
binding affinity
;
ND
;
N-domain
;
NMR
;
nuclear magnetic resonance
;
NOE
;
nuclear Overhauser effect
;
Tm
;
pro
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
3.
Design, synthesis and pharmacological evaluation of 4,5-diarylisoxazols bearing amino acid residues within the 3-amido motif as potent heat shock protein
90
(Hsp
90
) inhibitors
作者:
Chi Zhang
a
;
c
;
1
;
Xin Wang
b
;
d
;
1
;
Hongchun Liu
b
;
Minmin Zhang
b
;
Meiyu Geng
b
;
Liping Sun
a
;
chslp@cpu.edu.cn
;
Aijun Shen
b
;
shenaj@simm.ac.cn
;
Ao Zhang
c
;
aozhang@simm.ac.cn
关键词:
Diarylisoxazole
;
Resorcinol
;
Amino acid
;
Hsp
90
inhibitor
;
Antiproliferative effect
刊名:European Journal of Medicinal Chemistry
出版年:2017
4.
Formulation and purification of therapeutic dose of
90
Y-labeled peptides: Some interesting radiochemistry aspects
作者:
Rubel Chakravarty
;
Sudipta Chakraborty
;
sudipta@barc.gov.in
;
Ashutosh Dash
关键词:
Neuroendocrine tumors
;
90
Y
;
DOTA-TATE
;
Therapeutic dose
;
90
Sr/
90
Y generator
;
Radionuclidic purity
刊名:Applied Radiation and Isotopes
出版年:2017
5.
Design, synthesis and biological evaluation of alkylamino biphenylamides as Hsp
90
C-terminal inhibitors
作者:
Gaurav Garg
;
Huiping Zhao
;
Brian S.J. Blagg
;
bblagg@ku.edu
关键词:
Heat shock protein
90
;
Hsp
90
C-terminal inhibitors
;
Alkylamino biphenylamides
;
Structure-activity relationship
;
Breast cancer
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
6.
Design, synthesis and biological evaluation of 7-(aryl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinoline derivatives as potential Hsp
90
inhibitors and anticancer agents
作者:
Sina Omid Malayeri
a
;
b
;
Khalil Abnous
c
;
Atefeh Arab
d
;
Maryam Akaberi
e
;
Soghra Mehri
c
;
Afshin Zarghi
f
;
Razieh Ghodsi
a
;
b
;
ghodsir@mums.ac.ir
关键词:
Quinolines
;
Heat Shock Protein
90
;
Anti-cancer activity
;
Her2
;
Molecular docking
;
Hsp
90
inhibitor
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
7.
A useful PET probe [
11
C]BU9
90
08 with ultra-high specific radioactivity for small animal PET imaging of I
2
-imidazoline receptors in the hypothalamus
作者:
Kazunori Kawamura
a
;
kawamura.kazunori@qst.go.jp
;
Yoko Shimoda
a
;
Joji Yui
a
;
Yiding Zhang
a
;
Tomoteru Yamasaki
a
;
Hidekatsu Wakizaka
b
;
Akiko Hatori
a
;
Lin Xie
a
;
Katsushi Kumata
a
;
Masayuki Fujinaga
a
;
Masanao Ogawa
a
;
c
;
Yusuke Kurihara
a
;
c
;
Nobuki Nengaki
a
;
c
;
Ming-Rong Zhang
a
关键词:
Ultra-high specific radioactivity
;
11C
;
Imidazoline receptors
;
I2
;
BU9
90
08
;
PET
刊名:Nuclear Medicine and Biology
出版年:2017
8.
Pilot-scale whole-cell biocatalysis for the hydroxylation of cyclosporine derivative, FR
90
1459, at higher concentrations by Lentzea sp. 7887 using soybean flour as a novel substrate dispersant
作者:
Tetsuya Yabutani
1
;
3
;
tetsuya.yabutani@astellas.com
;
Shiho Shimizu
2
;
Hideo Nakano
3
关键词:
Bioconversion
;
Whole-cell biocatalysis
;
FR
90
1459
;
Lentzea
;
Soybean flour
;
Hydroxylation
;
Pilot scale
;
Dispersant
;
Cyclosporine derivative
刊名:Journal of Bioscience and Bioengineering
出版年:2017
9.
Process improvement for the safe delivery of multidisciplinary-executed treatments—A case in Y-
90
microspheres therapy
作者:
Bin Cai
1
;
Michael B. Altman
1
;
Jose Garcia-Ramirez
1
;
Jason LaBrash
1
;
S. Murty Goddu
1
;
Sasa Mutic
1
;
Parag J. Parikh
1
;
Jeffrey R. Olsen
1
;
Nael Saad
2
;
Jacqueline E. Zoberi
1
;
jzoberi@radonc.wustl.edu
关键词:
Process improvement
;
DMAIC
;
Y-
90
radioembolization
;
Electronic workflow management system
刊名:Brachytherapy
出版年:2017
10.
Identification of a putative FR
90
1469 biosynthesis gene cluster in fungal sp. No. 11243 and enhancement of the productivity by overexpressing the transcription factor gene frbF
作者:
Makoto Matsui
1
;
2
;
makoto.matsui@astellas.com
;
Tatsuya Yokoyama
1
;
2
;
Kaoru Nemoto
2
;
Toshitaka Kumagai
2
;
3
;
Goro Terai
4
;
5
;
Koichi Tamano
2
;
6
;
Masayuki Machida
2
;
6
;
Takashi Shibata
1
;
2
关键词:
Fungal sp. No. 11243
;
FR
90
1469
;
Secondary metabolite
;
Genomic analysis
;
Transcriptome
刊名:Journal of Bioscience and Bioengineering
出版年:2017
1
2
3
4
5
6
7
8
9
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