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在“Elsevier电子期刊”中，命中：18条，耗时：小于0.01 秒

1.Novel hybrid molecules based on 15-membered azalide as potential antimalarial agents

作者：Kristina Star?evi?^a ; ¹ ; Dijana Pe&scaron ; i?^a ; ³ ; Ana Toplak^a ; ² ; Goran Landek^a ; ³ ; Sulejman Alihod?i?^a ; ³ ; Esperanza Herreros^b ; Santiago Ferrer^b ; Radan Spaventi^a ; ³ ; Mihaela Peri?^a ; ^{mihaela.peric@mef.hr}

关键词：Malaria ; Antimalarial ; Azalide ; Quinoline ; Hybrid molecules ; Synthesis ; Plasmodium falciparum

刊名：European Journal of Medicinal Chemistry

出版年：2012

2.Valosin containing protein (VCP) interacts with macrolide antibiotics without mediating their anti-inflammatory activities

作者：Krunoslav Nuji?^a ; ^{krunoslav.nujic@glpg.com} ; Marjorie Smith^c ; ¹ ; ^{marjorie.a.smith@hotmail.co.uk} ; Michael Lee^b ; ^{michael.j.lee@gsk.com} ; Daniela Belamari?^a ; ² ; ^{daniela.belamaric@glpg.com} ; Linda Toma&scaron ; kovi?^a ; ² ; ^{linda.tomaskovic@glpg.com} ; Sulejman Alihod?i?^a ; ² ; ^{sulejman.alihodzic@glpg.com} ; Ivica Malnar^a ; ² ; ^{ivica.malnar@glpg.com} ; Denis Polan?ec^a ; ² ; ^{denis.polancec@glpg.com} ; Klaus Schneider^b ; ³ ; ^{Klaus.Schneider@merckgroup.com} ; Vesna Erakovi? Haber^a ; ² ; ^{vesna.erakovichaber@glpg.com}

关键词：Macrolide ; Chemical proteomics ; Target identification ; Valosin containing protein ; Inflammation

刊名：European Journal of Pharmacology

出版年：2012

3.Novel desosamine-modified 14- and 15-membered macrolides without antibacterial activity

作者：Ivana Palej Jakopovi?^a ; ^&dagger ; ; Mirjana Bukvi? Kraja?i?^a ; ^&dagger ; ; Maja Matanovi? &Scaron ; kugor^a ; ^&dagger ; ; Vlado &Scaron ; timac^a ; ^&dagger ; ; Dijana Pe&scaron ; i?^a ; ^&dagger ; ; Ines Vujasinovi?^a ; ^&dagger ; ; Sulejman Alihod?i?^a ; ^&dagger ; ; Hana ?ip?i? Paljetak^b ; Goran Kragol^a ; ^&dagger ; ; ^{goran.kragol@glpg.com}

关键词：Macrolide ; 1 ; 3-Oxazolidin-2-one ; N-alkylations ; Antibacterial activity

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2012

4.Fluorescently labeled macrolides as a tool for monitoring cellular and tissue distribution of azithromycin

作者：Mario Matija?i? ; Vesna Muni? Kos ; Krunoslav Nuji? ; Snje?ana ?u?i? ; Jasna Padovan ; Goran Kragol ; Sulejman Alihod?i? ; Boris Mildner ; Donatella Verbanac ; Vesna Erakovi? Haber

关键词：Azi ; azithromycin ; clari ; clarithromycin ; DMSO ; dimethyl-sulphoxide ; FITC ; fluorescein isothiocyanate ; GTTR ; gentamicin labeled with Texas Red ; IL-6 ; interleukin-6 ; LPS ; lipopolysaccharide ; MCP-1 ; macrophage chemotactic protein 1 ; CCL2 ; MIC ; minimal inhib

刊名：Pharmacological Research

出版年：2012

5.Synthesis, activity and pharmacokinetics of novel antibacterial 15-membered ring macrolones

作者：Andrea Fajdetić ; Adrijana Vinter ; Hana Č ; ipč ; ić ; Paljetak ; Jasna Padovan ; Ivana Palej Jakopović ; Samra Kapić ; Sulejman Alihodž ; ić ; Darko Filić ; Marina Modrić ; Nada Koš ; utić ; -Hulita ; Roberto Antolović ; Zrinka Ivezić ; Schoenf

关键词：Macrolide ; Resistance ; Antibacterial activity ; Pharmacokinetics ; Oral bioavailability

刊名：European Journal of Medicinal Chemistry

出版年：2011

6.Discovery of novel ureas and thioureas of 3-decladinosyl-3-hydroxy 15-membered azalides active against efflux-mediated resistant Streptococcus pneumoniae

作者：Mirjana Bukvić ; Krajač ; ić ; ^a ; ^† ; ; ^{mirjana.bukvic@gmail.com} ; Miljenko Dumić ; ^b ; Predrag Novak^c ; Mario Cindrić ; ^d ; Sanja Koš ; trun^a ; ^† ; ; Andrea Fajdetić ; ^a ; ^† ; ; Sulejman Alihodž ; ić ; ^a ; ^† ; ; Karmen Brajš ; a^a ; ^† ; ; Nedjeljko Kujundž ; ić ; ^a ; ^† ;

关键词：Azalides ; 3-Decladinosyl ; Ureas ; Thioureas ; Synthesis ; Antibacterial activity

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2011

7.Synthesis of macrolones with central piperazine ring in the linker and its influence on antibacterial activity

作者：Samra ; Kapi?^a ; ; ^{samra.kapic@glpg.com} ; Hana ; ?ip?i? Paljetak^a ; ; ^&dagger ; ; Ivana ; Palej Jakopovi?^a ; Andrea ; Fajdeti?^a ; Marina ; Ilija&scaron ; ^a ; Vlado ; &Scaron ; timac^a ; Karmen ; Braj&scaron ; a^a ; David J. ; Holmes^b ; John ; Berge^c ; Sulejman ; Alihod?i?^a

关键词：Antimicrobial activity ; Macrolides ; Piperazine ; Quinolone ; Structure&ndash ; activity relationship

刊名：Bioorganic and Medicinal Chemistry

出版年：2011

8.Synthesis and activity of new macrolones: Conjugates between 6(7)-(2?aminoethyl)-amino-1-cyclopropyl-3-carboxylic acid (2?hydroxyethyl) amides and 4?propenoyl-azithromycin

作者：Samra ; Kapi?^a ; ; ^&dagger ; ; ; ^{samra.kapic@glpg.com} ; Andrea ; Fajdeti?^a ; ; ^&dagger ; ; Sanja ; Ko&scaron ; trun^a ; ; ^&dagger ; ; Ana ; ?iko&scaron ; ^a ; ; ^&dagger ; ; Hana ?ip?i? ; Paljetak^a ; ; ^&Dagger ; ; Roberto ; Antolovi?^a ; ; ^§ ; ; David J. ; Holmes^b ; Sulejman ; Alihod?i?^a ; ; ^&dagger ;

关键词：Antimicrobial activity ; Macrolides ; Macrolones ; Quinolone ; Structure&ndash ; activity relationship

刊名：Bioorganic and Medicinal Chemistry

出版年：2011

9.Novel 8a-aza-8a-homoerythromycin—4″-(3-substituted-amino)propionates with broad spectrum antibacterial activity

作者：Antun Hutinec ; Marko Đ ; erek ; Gorjana Lazarevski ; Vitomir Š ; unjić ; Hana Č ; ipč ; ić ; Paljetak ; Sulejman Alihodž ; ić ; Vesna Eraković ; Haber ; Miljenko Dumi

关键词：Macrolide ; Azalide ; 8a-aza-8a-Homoerythromycin— ; 4″ ; -(3-substituted-amino)propionates ; Antibacterial activity ; Resistance

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2010

10.6-Alkylquinolone-3-carboxylic acid tethered to macrolides synthesis and antimicrobial profile

作者：Samra Kapić ; Hana Č ; ipč ; ić ; Paljetak ; Sulejman Alihodž ; ić ; Roberto Antolović ; Vesna Eraković ; Haber ; Richard L. Jarvest ; David J. Holmes ; John P. Broskey ; Er

关键词：Tethered macrolides ; 6-(ω ; -Carboxy)-alkyl-N(1)-ethyl-3-carboxylquinolones ; Antimicrobial activity ; Structure– ; activity relationship

刊名：Bioorganic and Medicinal Chemistry

出版年：2010

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