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CNKI会议论文(3)
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CNKI期刊论文0611(1)
知网期刊论文(211)
万方学位论文(1)
在“
Elsevier电子期刊
”中,
命中:
689
条,耗时:小于0.01 秒
在所有数据库中总计命中:
540
条
1.
Much more than you expected: The non-
DHFR
-mediated effects of methotrexate
作者:
Martin Sramek
;
Jakub Neradil
;
Renata Veselska
;
veselska@sci.muni.cz
关键词:
ADA
;
adenosine deaminase
;
AICAR
;
5-aminoimidazole-4-carboxamide ribonucleotide
;
ALL
;
acute lymphoblastic leukemia
;
ATIC
;
AICAR transformylase
;
ATRA
;
all-trans retinoic acid
;
DHF
;
dihydrofolate
;
DHFR
;
dihydrofolate reductase
;
E2F1
;
E2F transcription factor 1
;
FAICAR
;
5-formaminoimidazole-4-carboxamide ribonucleotide
;
FGAR
;
formylglycinamide ribonucleotide
;
FPGS
;
folylpolyglutamate synthetase
;
GAR
;
glycinamide ribonucleotide
;
GART
;
GAR transformylase
;
Glo1
;
glyoxalase I
;
HATs
;
histone acetyltransf
刊名:Biochimica et Biophysica Acta (BBA) - General Subjects
出版年:2017
2.
Structure-based analysis of Bacilli and plasmid dihydrofolate reductase evolution
作者:
Mona Alotaibi
a
;
b
;
monaotaibi@ksu.edu.sa
;
Ben Delos Reyes
a
;
Tin Le
a
;
Phuong Luong
a
;
Faramarz Valafar
c
;
faramarz@mail.sdsu.edu
;
Robert P. Metzger
a
;
rmetzger@mail.sdsu.edu
;
Gary B. Fogel
d
;
gfogel@natural-selection.com
;
David Hecht
a
;
e
;
dhecht@swccd.edu
关键词:
Dihydrofolate Reductase
;
DHFR
;
Structure-based Alignment
;
Phylogeny
;
Evolution
;
Plasmid evolution
;
Horizontal Gene Transfer
;
Network of Coupled Protein Motion
刊名:Journal of Molecular Graphics and Modelling
出版年:2017
3.
Perturbation of genome integrity to fight pathogenic microorganisms
作者:
Kinga Nyí
;
ri
;
nyiri.kinga@ttk.mta.hu
;
Beá
;
ta G. Vé
;
rtessy
;
vertessy@mail.bme.hu
关键词:
CH2THF
;
5
;
10-methylene tetrahydrofolate
;
DCD
;
dCTP deaminase
;
DCD-DUT
;
bifunctional dCTP deaminase&ndash
;
dUTPase
;
DUT
;
dUTPase
;
DHF
;
dihydrofolate
;
DHFR
;
dihydrofolate reductase
;
DHFR
&ndash
;
TS
;
bifunctional dihydrofolate reductase &ndash
;
thymidylate synthase
;
FAD
;
flavin adenine dinucleotide
;
SHMT
;
serine hydroxymethyltransferase
;
THF
;
tetrahydrofolate
;
TK
;
thymidine kinase
;
TS
;
ThyX
;
classical and flavin-dependent thymidylate synthase
;
TMPK
;
dTMP kinase
;
Ugi
;
uracil-DNA glycosylase inhibitor
刊名:Biochimica et Biophysica Acta (BBA) - General Subjects
出版年:2017
4.
Design, synthesis, docking studies and biological evaluation of novel dihydro-1,3,5-triazines as human
DHFR
inhibitors
作者:
Xiaotian Zhou
a
;
Kuaile Lin
a
;
Xiang Ma
b
;
Wai-Keung Chui
c
;
Weicheng Zhou
a
;
zhouweicheng58@163.com
关键词:13 ;
5-Triazine
;
Triazaspirodiene
;
h
DHFR
inhibitors
;
Docking study
;
Antitumor activities
刊名:European Journal of Medicinal Chemistry
出版年:2017
5.
H19 mediates methotrexate resistance in colorectal cancer through activating Wnt/β-catenin pathway
作者:
Ke-feng Wu
a
;
1
;
Wei-Cheng Liang
b
;
1
;
Lu Feng
c
;
Jian-xin Pang
d
;
Mary Miu-Yee Waye
b
;
Jin-Fang Zhang
c
;
Wei-Ming Fu
d
;
fuweiming76@smu.edu.cn
关键词:
CRC
;
colorectal cancer
;
DHFR
;
dihydrofolate reductase
;
DMEM
;
Dulbecco's modified Eagle's medium
;
lncRNAs
;
long or large noncoding RNAs
;
HT-29-R
;
MTX-resistant colorectal cell line HT-29
;
MDR1
;
multi-drug resistance 1
;
MTT
;
3-(4
;
5-Dimethylthiazol-2-yl)-2
;
5-diphenyltetrazolium bromide
;
MTX
;
methotrexate
;
PI
;
propidium iodide
;
siRNAs
;
small interfering RNAs
;
siH19
;
siRNAs specifically target human H19
;
pH19
;
the H19 overexpressing vector
刊名:Experimental Cell Research
出版年:2017
6.
Improving the secretory capacity of Chinese hamster ovary cells by ectopic expression of effector genes: Lessons learned and future directions
作者:
Henning Gram Hansen
a
;
hgra@biosustain.dtu.dk
;
Nu&scaron
;
a Pristov&scaron
;
ek
a
;
Helene Faustrup Kildegaard
a
;
Gyun Min Lee
a
;
b
;
gyunminlee@kaist.ac.kr
关键词:
ATF6c
;
activating transcription factor 6
;
CHO
;
Chinese hamster ovary
;
DHFR
;
dihydrofolate reductase
;
effector gene
;
a transgene ectopically expressed with the purpose of obtaining a phenotypic change
;
IE
;
inducible expression
;
EPO
;
erythropoietin
;
ER
;
endoplasmic reticulum
;
HEK
;
human embryonic kidney
;
MAb
;
monoclonal antibody
;
pcd
;
pg per cell per day
;
PDI
;
protein disulphide isomerase
;
PTM
;
post-translational modification
;
qp
;
specific protein productivity
;
r-protein
;
recombinant protein
;
SCS
刊名:Biotechnology Advances
出版年:2017
7.
Correlated Motions in the
DHFR
-NADPH Complex
刊名:Biophysical Journal
出版年:2017
8.
Synthesis and molecular docking against dihydrofolate reductase of novel pyridin-N-ethyl-N-methylbenzenesulfonamides as efficient anticancer and antimicrobial agents
作者:
Khaled F. Debbabi
a
;
b
;
khaled_debbabi@yahoo.fr
;
Mahmoud S. Bashandy
a
;
c
;
bashandy_sci@yahoo.com
;
Sami A. Al-Harbi
a
;
sadharbi@uqu.edu.sa
;
Enas H. Aljuhani
d
;
Hamed M. Al-Saidi
a
关键词:
Benzenesulfonamide
;
Pyridine
;
Anticancer
;
Antimicrobial
;
Molecular docking
刊名:Journal of Molecular Structure
出版年:2017
9.
Design, synthesis, structure-activity relationship and mechanism of action studies of a series of 4-chloro-1-phthalazinyl hydrazones as a potent agent against Leishmania braziliensis
作者:
Angel H. Romero
a
;
angel.romero12@ucv.ve
;
Rafael Medina
b
;
Anamarí
;
a Alcala
c
;
Yael Garcí
;
a-Marchan
c
;
Jorge Nú
;
ñ
;
ez-Duran
c
;
Jacques Leañ
;
ez
c
;
Ali Mijoba
c
;
Carlos Ciangherotti
d
;
Xenó
;
n Serrano-Martí
;
n
c
;
Simó
;
n E. Ló
;
pez
a
;
slopez@usb.ve
关键词:
Leishmania braziliensis
;
Antileishmanial activity
;
Superoxide dismutase
;
Promastigotes
;
Phthalazine
;
Nitroheterocycle
刊名:European Journal of Medicinal Chemistry
出版年:2017
10.
The enigmatic conservation of enzyme dynamics in evolution
作者:
Amnon Kohen
amnon-kohen@uiowa.edu
关键词:
DHFR
;
dihydrofolate reductase
;
ec
DHFR
;
Escherichia coli
DHFR
;
NADPH
;
reduced nicotinamide adenine dinucleotide phosphate
;
NADP+
;
oxidized nicotinamide adenine dinucleotide phosphate
;
DHF
;
7
;
8-dihydrofolate
;
THF
;
5
67 ;
8-tetrahydrofolate
;
Tris
;
tris(hydroxymethyl)aminomethane
;
MES
;
2-(morpholino) ethanesulfonic acid
;
MTEN buffer
;
50
;
mM MES
;
25
;
mM Tris
;
25
;
mM ethanolamine
;
and 100
;
mM sodium chloride
;
KIE
;
kinetic isotope effect
;
KIEint
;
intrinsic KIE
;
KIEobs
;
observed KIE
;
fs
刊名:Perspectives in Science
出版年:2016
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