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在“Elsevier电子期刊”中，命中：9条，耗时：0.0349824 秒

在所有数据库中总计命中：29条

1.Structural basis of Escherichia coli nitroreductase NfsB triple mutants engineered for improved activity and regioselectivity toward the prodrug CB1954

作者：Jing Bai^a ; Jun Yang^a ; ^{junyang@dlut.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Yong Zhou^b ; Qing Yang^a

关键词：Escherichia coli nitroreductase NfsB ; CB1954 ; Protein engineering ; X-ray structure

刊名：Process Biochemistry

出版年：2015

2.Structure-based development of bacterial nitroreductase against nitrobenzodiazepine-induced hypnosis

作者：Shiuan-Woei LinWu^a ; Che-An Wu^b ; Fu-Chuo Peng^b ; Andrew H.-J. Wang^a ; ^{ahjwang@gate.sinica.edu.tw}

关键词：Nitrobenzodiazepine ; Escherichia coli type I nitroreductase NfsB ; Flunitrazepam ; Rational protein design ; Antidote

刊名：Biochemical Pharmacology

出版年：2012

3.Discovery and evaluation of Escherichia coli nitroreductases that activate the anti-cancer prodrug CB1954

作者：G.A. Prosser ; J.N. Copp ; S.P. Syddall ; E.M. Williams ; J.B. Smaill ; W.R. Wilson ; A.V. Patterson ; D.F. Ackerley

关键词：CB1954 ; Nitroreductase ; SOS chromotest ; GDEPT ; Nitroaromatic prodrug

刊名：Biochemical Pharmacology

出版年：2010

4.Characterization of Escherichia coli

作者：Shiuan-Woei LinWu ; Cheng-Jie Syu ; Yu-Lian Chen ; Andrew H.-J. Wang ; Fu-Chuo Peng

关键词：Nitrobenzodiazepine ; Rat jejunal microflora ; Escherichia coli nitroreductase NfsB ; Flunitrazepam ; NADPH– ; cytochrome P450 reductase

刊名：Biochemical Pharmacology

出版年：2009

5.Testing double mutants of the enzyme nitroreductase for enhanced cell sensitisation to prodrugs: Effects of combining beneficial single mutations

作者：Mansooreh Jaberipour ; Simon O. Vass ; Christopher P. Guise ; Jane I. Grove ; Richard J. Knox ; Longqin Hu ; Eva I. Hyde ; Peter F. Searle

关键词：Nitroreductase ; Prodrugs ; CB1954 (5-[(aziridin-1-yl]-2 ; 4-dinitrobenzamide) ; Virus directed enzyme prodrug therapy (VDEPT) ; Cancer gene therapy

刊名：Biochemical Pharmacology

出版年：2010

6.305 POSTER Structure–activity relationships for lipophilic dinitrobenzamide mustards as prodrugs for Escherichia coli NfsB nitroreductase

作者：S. Sydall ; A. Ashoorzadeh ; G.A. Atwell ; J.B. Smaill ; W.R. Wilson ; W.A. Denny ; A.V. Patterson

刊名：European Journal of Cancer Supplements

出版年：2008

7.Identification and characterization of SnrA, an inducible oxygen-insensitive nitroreductase in Salmonella enterica serovar Typhimurium TA1535

作者：Nokhbeh ; M.R. ; Boroumandi ; S. ; Pokorny ; N. ; Koziarz ; P. ; Paterson ; E.S. ; Lambert ; I.B.

关键词：SnrA ; Salmonella typhimurium nitroreductase A ; NfsA ; Escherichia coli nitroreductase A ; NfsB ; E. coli nitroreductase B ; FMN ; flavine mononucleotide ; Salmonella ; Nitroreductase ; FMN oxidoreductase ; NfsA ; SoxRS regulon

刊名：Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

出版年：2002

8.Nitrofuran resistance pathways in Escherichia coli: The role of mutations in NfsA and NfsB

作者：Lambert ; Iain ; Whiteway ; Jacqui ; Koziarz ; Peter ; Veall ; John ; Hoecker ; Birte

关键词：Nitroreductase ; Nitrofuran ; Mutagenesis

刊名：Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

出版年：1997

9.Nitrofuran resistance pathways in Escherichia coli: The role of mutations in NfsA and NfsB

作者：Lambert ; Iain ; Whiteway ; Jacqui ; Koziarz ; Peter ; Veall ; John ; Hoecker ; Birte

关键词：Nitroreductase ; Nitrofuran ; Mutagenesis

刊名：Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

出版年：1997

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