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在“Elsevier电子期刊”中，命中：47,607条，耗时：小于0.01 秒

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1.New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT₇ and 5-HT_1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies

作者：Sebastiano Intagliata^a ; ¹ ; ^{s.intagliata@studium.unict.it} ; Maria N. Modica^a ; ¹ ; Valeria Pittalà ; ^a ; Loredana Salerno^a ; Maria A. Siracusa^a ; Alfredo Cagnotto^b ; Mario Salmona^b ; Rafał Kurczab^c ; Giuseppe Romeo^a

关键词：5-HT7 receptor ligands ; 5-HT1A receptor ligands ; Long-chain arylpiperazines ; Molecular modeling

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

2.A novel role for PHT1 in the disposition of l-histidine in brain: In vitro slice and in vivo pharmacokinetic studies in wildtype and Pht1 null mice

作者：Xiao-Xing Wang^a ; ^{xiaoxing@umich.edu} ; Yongjun Hu^a ; ^{yongjun@umich.edu} ; Richard F. Keep^b ; ^{rkeep@umich.edu} ; Noriko Toyama-Sorimachi^c ; ^{nsorima@ri.ncgm.go.jp} ; David E. Smith^a ; ^{smithb@umich.edu}

关键词：PHT1 ; l-Histidine ; Pharmacokinetics ; Biodistribution ; Brain ; Mice

刊名：Biochemical Pharmacology

出版年：2017

3.In vivo evaluation of [¹⁸F]FECIMBI-36, an agonist 5-HT_2A/2C receptor PET radioligand in nonhuman primate

作者：Jaya Prabhakaran^a ; ^b ; Kiran Kumar Solingapuram Sai^c ; Francesca Zanderigo^a ; ^b ; Harry Rubin-Falcone^a ; Matthew J. Jorgensen^d ; Jay R. Kaplan^d ; Katharine I. Tooke^a ; Akiva Mintz^c ; J. John Mann^a ; ^b ; J.S. Dileep Kumar^b ; ^{kumardi@nyspi.columbia.edu}

关键词：5-HT ; 5-HT2A/2CR ; Agonist ; PET ; Radiotracer

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

4.5-HT1A receptor (HTR1A) 5′ region haplotypes significantly affect protein expression in vitro

作者：Xue Wu ; Jun Yao ; Mei Ding ; Zhang-sen Shi ; Feng-ling Xu ; Jing-jing Zhang ; Bao-jie Wang ; ^{wangbj77@163.com}

关键词：HTR1A ; Polymorphism ; Promoter ; Transcription ; Schizophrenia

刊名：Neuroscience Letters

出版年：2017

5.Characterization of recombination in P3HT:fullerene blends: Clarifying the influence of interfacial states

作者：Simon Sandé ; n ; ^{ssanden@abo.fi} ; Nora M. Wilson ; Mathias Nyman ; Ronald Ö ; sterbacka

关键词：Photoinduced absorption ; Bulk-heterojunction ; Recombination ; ICBA ; P3HT ; Interfacial dipole

刊名：Organic Electronics

出版年：2017

6.Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b

作者：Sivaraman Padavattan^a ; Viswanathan Thiruselvam^b ; Toshie Shinagawa^c ; Kazuya Hasegawa^d ; Takashi Kumasaka^d ; Shunsuke Ishii^c ; Thirumananseri Kumarevel^a ; ^e ; ^{kumarevel.thirumananseri@riken.jp}

关键词：hTh2a ; hTh2b ; Testis-specific histone variants ; Nucleosome ; Reprogramming

刊名：Biophysical Chemistry

出版年：2017

7.A facile one-pot regioselective synthesis of functionalized novel benzo[f]chromeno[4,3-b][1,7]naphthyridines and benzo[f][1,7]naphthyridines via an imino Diels-Alder reaction

作者：Sateesh Kumar Arepalli^a ; Byeongwoo Park^a ; Jae-Kyung Jung^a ; Kiho Lee^b ; Heesoon Lee^a ; ^{medchem@chungbuk.ac.kr}

关键词：13H-Benzo[f]chromeno[4 ; 3-b][1 ; 7]naphthyridines ; 1 ; 3-Diphenylbenzo[f][1 ; 7]naphthyridines ; Imino Diels-Alder reaction ; Atom economy ; One-pot multicomponent reaction

刊名：Tetrahedron Letters

出版年：2017

8.The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT_1A receptor over α₁-adrenoceptor and D₂-like receptor subtypes

作者：Fabio Del Bello^a ; ¹ ; Alessandro Bonifazi^a ; ^b ; ¹ ; Mario Giannella^a ; Gianfabio Giorgioni^a ; Alessandro Piergentili^a ; Riccardo Petrelli^a ; Carlo Cifani^a ; Maria Vittoria Micioni Di Bonaventura^a ; Thomas M. Keck^b ; ^c ; ^d ; Angelica Mazzolari^e ; Giulio Vistoli^e ; Antonio Cilia^f ; Elena Poggesi^f ; Rosanna Matucci^g ; Wilma Quaglia^a ; ^{wilma.quaglia@unicam.it}

关键词：5-HT1A receptor ; α1-Adrenoceptor subtypes ; D2-like receptor subtypes ; Selective 5-HT1A receptor agonists ; Docking studies ; Anxiolytic effect

刊名：European Journal of Medicinal Chemistry

出版年：2017

9.New therapeutic opportunities for 5-HT₂ receptor ligands

作者：Luc Maroteaux^b ; ¹ ; Estelle Ayme-Dietrich^a ; ¹ ; Gaë ; lle Aubertin-Kirch^a ; Sophie Banas^b ; Emily Quentin^b ; Roland Lawson^a ; Laurent Monassier^a ; ^{laurent.monassier@unistra.fr}

关键词：5-HT2 receptors ; Selectivity ; Pathological function ; Therapeutic track

刊名：Pharmacology & Therapeutics

出版年：2017

10.Serotonin Signaling through Prefrontal Cortex 5-HT_1A Receptors during Adolescence Can Determine Baseline Mood-Related Behaviors

作者：Alvaro L. Garcia-Garcia¹ ; Qingyuan Meng¹ ; Sarah Canetta² ; Alain M. Gardier³ ; Bruno P. Guiard³ ; Christoph Kellendonk² ; ⁴ ; ⁵ ; Alex Dranovsky¹ ; ^{ad722@cumc.columbia.edu} ; E. David Leonardo¹ ; ⁶ ; ^{el367@cumc.columbia.edu}

关键词：serotonin ; 5-HT1A ; depression ; anxiety ; development ; adolescence ; mPFC ; DRN

刊名：Cell Reports

出版年：2017

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