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在“Elsevier电子期刊”中，命中：25条，耗时：0.0139924 秒

在所有数据库中总计命中：842条

1.Reducing Treatment-Related Mortality Did Not Improve Outcomes of Allogeneic Myeloablative Hematopoietic Cell Transplantation for High-Risk Multiple Myeloma: A University of Michigan Prospective Series

作者：Attaphol Pawarode¹ ; ^{pawarode@med.umich.edu" class="auth_mail" title="E-mail the corresponding author} ; Shin Mineishi² ; Pavan Reddy¹ ; Thomas M. Braun³ ; Yasser A. Khaled⁴ ; Sung W. Choi¹ ; John M. Magenau¹ ; Andrew C. Harris¹ ; James A. Connelly¹ ; Carrie L. Kitko¹ ; Brian L. Parkin¹ ; Steven C. Goldstein¹ ; Gregory A. Yanik¹ ; John E. Levine¹ ; James L. Ferrara⁵ ; Daniel R. Couriel¹

关键词：Multiple myeloma ; Allogeneic ; Myeloablative ; Reduced toxicity ; Prospective ; Fludarabine ; Busulfan

刊名：Biology of Blood and Marrow Transplantation

出版年：2016

2.Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK)

作者：Colin H. MacKinnon ; Kevin Lau ; Jason D. Burch ; Yuan Chen ; Jonathon Dines ; Xiao Ding ; Charles Eigenbrot ; Alex ; er Heifetz ; Allan Jaochico ; Adam Johnson ; Joachim Kraemer ; Susanne Kruger ; Thomas M. Kr眉lle ; Marya Liimatta ; Justin Ly ; Rosemary Maghames ; Christian A.G.N. Montalbetti ; Daniel F. Ortwine ; Yol ; a P茅rez-Fuertes ; Steven Shia ; et al.

关键词：ITK inhibitor ; TCR signalling ; Benzothiazole ; Anti-inflammatory ; Asthma ; SAR

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：1 December, 2013

3.Optimisation of ITK inhibitors through successive iterative design cycles

作者：Matthias Herdemann^† ; ; ^a ; Alexander Weber ; ^‡ ; ; ^a ; ^{alexander.weber@boehringer-ingelheim.com} ; Jé ; rô ; me Jonveaux^a ; Frank Schwoebel^§ ; ; ^a ; Michael Stoeck^a ; Isabelle Heit ; ^a ; ^{isabelle.heit@nycomed.com}

关键词：Interleukin-2 inducible T cell kinase ; Lead optimisation ; In vivo testing ; Anti-CD3 IL-2 mouse model

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2011

4.Discovery of potent inhibitors of interleukin-2 inducible T-cell kinase (ITK) through structure-based drug design

作者：Brian N. Cook ; Jö ; rg Bentzien ; Andre White ; Peter A. Nemoto ; Ji Wang ; Chuk C. Man ; Fariba Soleymanzadeh ; Hnin Hnin Khine ; Mohammed A. Kashem ; Stanley Z. Kugler Jr. ; John P. Wolak ; Gregory P. Roth

关键词：Kinase ; Structure-based drug design ; ITK ; Tec kinase ; SAR ; Inhibitor ; Benzimidazole

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2009

5.Imidazo[1,5-a]quinoxalines as irreversible BTK inhibitors for the treatment of rheumatoid arthritis

作者：Kyung-Hee ; Kim^a ; ; ^{khkim87@hotmail.com} ; ; ^{kyung-hee.kim@pfizer.com} ; Andreas ; Maderna^a ; Mark E. ; Schnute^a ; Martin ; Hegen^b ; Shashi ; Mohan^b ; Joy ; Miyashiro^b ; Laura ; Lin^b ; Evelyn ; Li^b ; Sean ; Keegan^b ; Jennifer ; Lussier^b ; Christopher ; Wrocklage^b ; Cheryl L. ; Nickerson-Nutter^b ; Arthur J. ; Wittwer^b ; Holly ; Soutter^c ; Nicole ; Caspers^c ; Seungil ; Han^c ; Ravi ; Kurumbail^c ; Kyri ; Dunussi-Joannopoulos^b ; John ; Douhan III^b ; Allan ; Wissner^a

关键词：BTK ; Autoimmune ; Rheumatoid arthritis ; Covalent kinase inhibitor ; Imidazo[1 ; 5-a]quinoxaline

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2011

6.5-Aminomethylbenzimidazoles as potent ITK antagonists

作者：Doris Riether ; René ; e Zindell ; Jennifer A. Kowalski ; Brian N. Cook ; Jö ; rg Bentzien ; Sté ; phane De Lombaert ; David Thomson ; Stanley Z. Kugler Jr. ; Donna Skow ; Leslie S. Martin ; Ernest L. Ray

关键词：ITK ; Interleukin-2 inducible T-cell kinase ; 5-Aminobenzimidazole

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2009

7.Hit-to-lead studies on benzimidazole inhibitors of ITK: Discovery of a novel class of kinase inhibitors

作者：Roger J. Snow ; Asitha Abeywardane ; Scot Campbell ; John Lord ; Mohammed A. Kashem ; Hnin Hnin Khine ; Josephine King ; Jennifer A. Kowalski ; Steven S. Pullen ; Teresa Roma ; et al.

关键词：ITK ; Kinase ; Kinase inhibitor ; Benzimidazole ; Inducible T cell kinase

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2007

8.Itk kinase inhibitors: Initial efforts to improve the metabolical stability and the cell activity of the benzimidazole lead

作者：Kevin J. Moriarty ; Michael Winters ; Lei Qiao ; Declan Ryan ; Renee DesJarlis ; Darius Robinson ; Brian N. Cook ; Mohammed A. Kashem ; Paul V. Kaplita ; Lisa H. Liu ; Thomas M. Farrell ; Hnin Hnin Khine ; Joseph

关键词：SAR ; Itk inhibitor ; Metabolic stability ; Liver microsomes

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2008

9.Proteasome inhibitors block HIV-1 replication by affecting both cellular and viral targets

作者：Liang Yu ; Venkatramanan Mohanram ; Oscar E. Simonson ; C.I. Edvard Smith ; Anna-Lena Spetz ; Abdalla J. Mohamed

关键词：HIV-1 ; Bortezomib ; Proteasome inhibitor ; NF-κB ; Itk ; LTR ; Transcription

刊名：Biochemical and Biophysical Research Communications

出版年：2009

10.Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors

作者：Jagabandhu Das ; Joseph A. Furch ; Chunjian Liu ; Robert V. Moquin ; James Lin ; Steven H. Spergel ; Kim W. McIntyre ; David J. Shuster ; Kathleen D. O’ ; Day ; Becky Penhallow et al.

关键词：Amino-(thioaryl)thiazoles ; Selective Itk inhibitor

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2006

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