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在“Elsevier电子期刊”中，命中：543条，耗时：0.0140001 秒

在所有数据库中总计命中：1,781条

1.Class I phosphatidylinositol 3-kinase inhibitors for cancer therapy

作者：Wennan Zhao^&dagger ; ; Yuling Qiu^&dagger ; ; Dexin Kong ; ^{kongdexin@tmu.edu.cn}

关键词：Phosphatidylinositol 3-kinase ; PI3K inhibitor ; Drug candidate ; Cancer therapy ; PI3K/mTOR selectivity ; Anticancer

刊名：Acta Pharmaceutica Sinica B

出版年：2017

2.Regulation of proteasome activity by P2Y₂ receptor underlies the neuroprotective effects of extracellular nucleotides

作者：Laura de Diego-Garcí ; a^a ; ^c ; Mercedes Ramí ; rez-Escudero^a ; Á ; lvaro Sebastiá ; n-Serrano^a ; ^c ; Juan Ignacio Diaz-Herná ; ndez^a ; ^d ; Jesú ; s Pintor^b ; José ; J. Lucas^d ; ^e ; Miguel Dí ; az-Herná ; ndez^a ; ^c ; ^{migueldiaz@ucm.es}

关键词：UPS ; Ubiquitin-Proteasome System ; P2Y2R ; P2Y2 receptor ; IP3 ; inositol 14 ; 5-trisphosphate ; MEK1/2 ; MAP kinase kinases ; ERK ; extracellular signal-regulated kinase ; PKC ; protein kinase C ; PKA ; protein kinase A ; PI3K ; inositol 14 ; 5-trisphosphate 3-kinases ; MAPK/ERK ; mitogen-activated protein kinases ; GFP ; green fluorescent protein ; YFP ; yellow fluorescent protein ; ATP ; adenosine triphosphate ; UTP ; uridine triphosphate ; PPADS ; pyridoxalphosphate-6-azophenyl-2&prime ; 4&prime ; -disulfonic acid ; Up4U

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

3.Elevated levels of alpha-synuclein blunt cellular signal transduction downstream of Gq protein-coupled receptors

作者：Mattia Volta ; ^{mattia.volta@eurac.edu} ; Alexandros A. Lavdas ; Julia Obergasteiger ; Christa Ü ; berbacher ; Anne Picard ; Peter P. Pramstaller ; Andrew A. Hicks ; Corrado Corti ; ^{corrado.corti@eurac.edu}

关键词：aSyn ; Alpha-synuclein ; PD ; Parkinson's disease ; PLCβ1 ; phospholipase Cβ1 ; PI(4 ; 5)P2 ; phosphoinositide-4 ; 5-bisphosphate ; Gq-PCRs ; Gq protein-coupled receptors ; IP3 ; inositol-14 ; 5-trisphosphate ; DAG ; diacylglycerol ; PKC ; protein kinase C ; MAPKs ; mitogen-activated protein kinase ; WT ; wild-type ; ERK1/2 ; extracellular-signal regulated kinase 1/2 ; 5-HT ; serotonin ; (CHO) ; Chinese hamster ovary cells ; FBS ; fetal bovine serum ; AP-1 ; activator protein-1 ; RT ; room temperature ; 5-HT ; serotonin ; SERCA ; sarc

刊名：Cellular Signalling

出版年：2017

4.Targeting calcium signaling in cancer therapy

作者：Chaochu Cui^a ; ^b ; Robert Merritt^b ; ^c ; Liwu Fu^a ; Zui Pan^b ; ^c ; ^d ; ^{zui.pan@uta.edu}

关键词：20-GPPD ; 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol ; CaM ; calmodulin ; CaMKII ; calmodulin-dependent protein kinase II ; CBD ; cannabidiol ; CBG ; cannabigerol ; CPZ ; capsazepine ; CRAC ; Ca2+ release-activated Ca2+ channel ; CTL ; cytotoxic T cells ; CYP3A4 ; cytochrome P450 3A4 ; ER/SR ; endoplasmic/sarcoplasmic reticulum ; HCX ; H+/Ca2+ exchangers ; IP3 ; inositol 14 ; 5-trisphosphate ; IP3R (1 ; 2 ; 3) ; IP3 receptor (type 1 ; type 2 ; type 3) ; mAb ; monoclonal antibody ; MCU ; mitochondrial Ca2+ uniporter ; MCUR1 ; MC

刊名：Acta Pharmaceutica Sinica B

出版年：2017

5.Specific expression and function of inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) in wild type and knock-out mice

作者：Ariane Scoumanne^a ; ¹ ; Patricia Molina-Ortiz^a ; Daniel Monteyne^b ; David Perez-Morga^b ; ^c ; Christophe Erneux^d ; Sté ; phane Schurmans^a ; ^{sschurmans@ulg.ac.be" class="auth_mail" title="E-mail the corresponding author}

关键词：Inositol 134 ; 5-tetrakisphosphate ; Inositol 14 ; 5-trisphosphate 3-kinase ; Itpkc ; Tissue expression ; Mouse

刊名：Advances in Biological Regulation

出版年：2016

6.Ibrutinib inhibition of Bruton protein-tyrosine kinase (BTK) in the treatment of B cell neoplasms

作者：Robert Roskoski Jr. ^{rrj@brimr.org" class="auth_mail" title="E-mail the corresponding author}

关键词：AS ; activation segment ; CLL ; chronic lymphocytic leukemia ; CS or C-spine ; catalytic spine ; CL ; catalytic loop ; HΦ or Φ ; hydrophobic ; IP3 ; inositol 14 ; 5 trisphosphate ; IP6 ; inositol 12345 ; 6 hexakisphosphate ; MCL ; mantle cell lymphoma ; MW ; molecular weight ; NSCLC ; non-small cell lung cancer ; PKA ; protein kinase A ; PIP2 ; phosphatidyl inositol 4 ; 5 bisphosphate ; PIP3 ; phosphatidyl inositol 34 ; 5 trisphosphate ; RA ; rheumatoid arthritis ; RS or R-spine ; regulatory spine ; Sh1 ; shell residue 1 ; WM ; W

刊名：Pharmacological Research

出版年：2016

7.Inositol(1,4,5)P₃ 3-kinase isoenzymes: Catalytic properties and importance of targeting to F-actin to understand function

作者：Christophe Erneux ; ^{cerneux@ulb.ac.be" class="auth_mail" title="E-mail the corresponding author} ; Somadri Ghosh ; Sandra Koenig

关键词：Inositol trisphosphate 3-kinase ; Inositol(14 ; 5)trisphosphate ; Inositol(134 ; 5)tetrakisphosphate ; Signal transduction

刊名：Advances in Biological Regulation

出版年：2016

8.Differential role of SNAP-25 phosphorylation by protein kinases A and C in the regulation of SNARE complex formation and exocytosis in PC12 cells

作者：Jing Gao^a ; Makiko Hirata^a ; ^b ; Akiko Mizokami^a ; Jin Zhao^a ; Ichiro Takahashi^b ; Hiroshi Takeuchi^c ; Masato Hirata^a ; ^{hirata1@dent.kyushu-u.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：CSP ; cysteine string protein ; FSK ; forskolin ; GST ; glutathione S-transferase ; Ins(14 ; 5)P3 ; d-myo-inositol 14 ; 5-trisphosphate ; KO ; knock out ; NA ; noradrenalin ; NSF ; N-ethylmaleimide-sensitive factor ; PKA ; cAMP-dependent protein kinase ; PKC ; protein kinase C ; PMA ; phorbol 12-myristate 13-acetate ; SDS ; sodium dodecyl sulfate ; SNAP-25 ; synaptosomal-associated protein of 25 ; kDa ; SNARE ; soluble NSF-attachment protein receptors ; VAMP ; vesicle-associated membrane protein ; WT ; wild type

刊名：Cellular Signalling

出版年：2016

9.Saline and osmotic stresses stimulate PLD/diacylglycerol kinase activities and increase the level of phosphatidic acid and proline in barley roots

作者：Maria V. Meringer^a ; Ana L. Villasuso^a ; ^{lvillasuso@exa.unrc.edu.ar" class="auth_mail" title="E-mail the corresponding author} ; Micaela Peppino Margutti^a ; Javier Usorach^a ; Susana J. Pasquaré ; ^b ; Norma M. Giusto^b ; Estela E. Machado^a ; Graciela E. Racagni^a

关键词：ABA ; abscisic acid ; CL ; cardiolipin ; DAG ; diacylglycerol ; DAG-k ; diacylglycerol kinase ; DGPP ; diacylglycerol pyrophosphate ; DGPPase ; diacylglycerol pyrophosphate phosphatase ; IAA ; indole-3-acetic acid ; IP3 ; inositol 14 ; 5-trisphosphate ; GA3 ; gibberellic acid ; GPL ; glycerophospholipids ; JA ; jasmonic acid ; LPPs ; lipid phosphate phosphatases ; PA ; phosphatidic acid ; PA-k ; phosphatidate kinase ; PAP2 ; phosphatidate phosphohydrolase type 2 ; PC ; phosphatidylcholine ; PE ; phosphatidylethanolamine ; PG ; pho

刊名：Environmental and Experimental Botany

出版年：2016

10.HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptor

作者：Felipe Paredes^a ; Valentina Parra^a ; Natalia Torrealba^a ; Mario Navarro-Marquez^a ; Damian Gatica^a ; Roberto Bravo-Sagua^a ; Rodrigo Troncoso^a ; ^b ; Christian Pennanen^a ; Clara Quiroga^c ; Mario Chiong^a ; Christa Caesar^d ; W. Robert Taylor^d ; ^e ; Jordi Molgó ; ^f ; Alejandra San Martin^e ; Enrique Jaimovich^g ; Sergio Lavandero^a ; ^g ; ^h ; ^{slavander@uchile.cl" class="auth_mail" title="E-mail the corresponding author}

关键词：ActD ; actinomycin D ; Ang II ; angiotensin II ; Cat ; catalase ; CHX ; cycloheximide ; CsA ; cyclosporine A ; Cyt-C ; cytochrome c ; ER ; endoplasmic reticulum ; ERAD ; ER-associated degradation ; ERE ; ER stress ; HERPUD1 ; homocysteine-induced ER protein ; ITPR ; inositol 14 ; 5-trisphosphate receptor ; JNK ; c-Jun N-terminal kinase ; MPP+ ; methylphenylpyridinium ; MPTP ; mitochondrial permeability transition pore ; Nox ; NAD(P)H oxidase ; RYR ; ryanodine receptor ; VSMC ; vascular smooth muscle cells ; XeB ; xestospongin B

刊名：Free Radical Biology and Medicine

出版年：2016

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