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在“Elsevier电子期刊”中，命中：2,165条，耗时：小于0.01 秒

在所有数据库中总计命中：14,233条

1.Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia

作者：Kaiwei Liang¹ ; ² ; Andrew G. Volk¹ ; ³ ; Jeffrey S. Haug² ; Stacy A. Marshall¹ ; Ashley R. Woodfin¹ ; Elizabeth T. Bartom¹ ; Joshua M. Gilmore² ; Laurence Florens² ; Michael P. Washburn² ; ⁴ ; Kelly D. Sullivan⁵ ; Joaquin M. Espinosa⁵ ; Joseph Cannova⁶ ; ⁷ ; Jiwang Zhang⁶ ; ⁷ ; Edwin R. Smith¹ ; John D. Crispino¹ ; ³ ; ⁸ ; Ali Shilatifard¹ ; ² ; ⁸ ; ⁹ ; ^{ash@northwestern.edu}

关键词：mixed-lineage leukemia ; MLL ; wild-type MLL ; MLL chimera ; UBE2O ; interleukin-1 ; IRAK4 ; IRAK1 ; super elongation complex ; SEC

刊名：Cell

出版年：2017

2.MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia

作者：Jon Kerry¹ ; Laura Godfrey¹ ; Emmanouela Repapi² ; Marta Tapia¹ ; Neil P. Blackledge³ ; Helen Ma⁴ ; Erica Ballabio¹ ; Sorcha O&rsquo ; Byrne⁵ ; Frida Ponthan⁶ ; Olaf Heidenreich⁶ ; Anindita Roy⁵ ; Irene Roberts¹ ; ⁵ ; Marina Konopleva⁴ ; Robert J. Klose³ ; Huimin Geng⁷ ; Thomas A. Milne¹ ; ⁸ ; ^{thomas.milne@imm.ox.ac.uk}

关键词：MLL ; MLL-AF4 ; DOT1L ; H3K79me2 ; leukemia ; epigenetic therapy ; drug combination therapy ; epigenetic spreading

刊名：Cell Reports

出版年：2017

3.Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification

作者：Deqing Hu¹ ; ² ; Xin Gao² ; Kaixiang Cao¹ ; Marc A. Morgan¹ ; Gloria Mas³ ; ⁴ ; Edwin R. Smith¹ ; Andrew G. Volk¹ ; ⁵ ; Elizabeth T. Bartom¹ ; John D. Crispino¹ ; ⁵ ; ⁷ ; Luciano Di Croce³ ; ⁴ ; ⁶ ; Ali Shilatifard¹ ; ² ; ⁷ ; ⁸ ; ^{ash@northwestern.edu}

关键词：Histone-Lysine N-Methyltransferase ; chromatin ; histone ; mouse embryonic stem cell ; embryonic development ; primordial germ cell ; gene expression regulation ; Mll2 ; Kmt2b ; CXXC domain

刊名：Molecular Cell

出版年：2017

4.Single-cell Sequencing Reveals Variants in ARID1A, GPRC5A and MLL2 Driving Self-renewal of Human Bladder Cancer Stem Cells

作者：Zhao Yang^a ; ¹ ; Chong Li^a ; ¹ ; Zusen Fan^a ; ¹ ; Hongjie Liu^b ; ^c ; ¹ ; Xiaolong Zhang^d ; ¹ ; Zhiming Cai^e ; ¹ ; Liqin Xu^f ; Jian Luo^f ; Yi Huang^d ; Luyun He^a ; Chunxiao Liu^g ; Song Wu^d ; ^{wusong@szu.edu.cn}

关键词：bladder cancer ; bladder cancer stem cells ; genetic alteration ; self-renewal ; single-cell sequencing ; tumor evolution

刊名：European Urology

出版年：2017

5.Transcriptional activation by MLL fusion proteins in leukemogenesis

作者：Akihiko Yokoyama^a ; ^b ; ^{yokoyama@kuhp.kyoto-u.ac.jp}

刊名：Experimental Hematology

出版年：2017

6.Structure-based design of ester compounds to inhibit MLL complex catalytic activity by targeting mixed lineage leukemia 1 (MLL1)-WDR5 interaction

作者：Dong-Dong Li^a ; Zhi-Hui Wang^a ; Wei-Lin Chen^a ; Yi-Yue Xie^a ; Qi-Dong You^a ; ^b ; ^{youqidong@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Xiao-Ke Guo^a ; ^b ; ^{kexin95@126.com" class="auth_mail" title="E-mail the corresponding author}

关键词：MLL1&ndash ; WDR5 interaction ; Histone methyltransferase ; Ester compounds ; Leukemia ; Docking

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

7.Compositional and functional diversity of canonical PRC1 complexes in mammals

作者：Katelyn E. Connelly^a ; Emily C. Dykhuizen^a ; ^b ; ^{edykhui@purdue.edu}

关键词：bps ; base pairs ; PcG ; Polycomb Group ; PRC1 ; Polycomb Repressive Complex 1 ; PRC2 ; Polycomb Repressive Complex 2 ; Pc ; Polycomb ; Ph ; Polyhomeotic ; Psc ; Posterior sex combs ; Sce ; Sex combs extra ; H3K27me3 ; histone H3 lysine 27 trimethylation ; SAM ; sterile alpha motif ; PCGF ; Polycomb Group Finger ; PHC ; human Polyhomeotic ; CBX ; chromobox homolog ; PREs ; Polycomb Response Elements ; MLL ; mixed lineage leukemia ; SWI/SNF ; Switch/sucrose non-fermentable ; PRE ; Polycomb Response Element ; ESC ; embryonic stem c

刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

出版年：2017

8.Anxiety provokes balance deficits that are selectively dopa-responsive in Parkinson’s disease

作者：Kaylena A. Ehgoetz Martens^a ; ^b ; Shannon C. Lefaivre^a ; Eric N. Beck^a ; Rebecca Chow^a ; Frederico Pieruccini-Faria^a ; Colin G. Ellard^b ; Quincy J. Almeida^a ; ^{qalmeida@wlu.ca}

关键词：AP ; anterior&ndash ; posterior ; COG ; center of gravity ; COP ; center of pressure ; HMD ; head-mounted display ; MLL ; medio-lateral ; PD ; Parkinson&rsquo ; s disease ; STAI ; State Trait Anxiety Inventory ; VR ; virtual reality

刊名：Neuroscience

出版年：2017

9.Unrelated Cord Blood Transplantation for Acute Leukemia Diagnosed in the First Year of Life: Outcomes and Risk Factor Analysis

作者：Annalisa Ruggeri¹ ; ² ; ^{annalisa.ruggeri@aphp.fr} ; Fernanda Volt² ; Franco Locatelli³ ; Gerard Michel⁴ ; Cristina Diaz de Heredia⁵ ; Manuel Abecasis⁶ ; Marco Zecca⁷ ; Ajay Vora⁸ ; Karima Yakouben⁹ ; Tracey A. O'Brien¹⁰ ; Stefano Giardino¹¹ ; Jacqueline Cornish¹² ; Vanderson Rocha² ; ¹³ ; Christina Peters¹⁴ ; Peter Bader¹⁵ ; Eliane Gluckman² ; ¹⁶ ; Jean Hugues Dalle⁹

关键词：Cord blood transplantation ; Infant ; Acute leukemia ; MLL-rearranged leukemia

刊名：Biology of Blood and Marrow Transplantation

出版年：2017

10.Human PRE-PIK3C2B, an intronic cis-element with dual function of activation and repression

作者：Jayant Maini^a ; Mohsen Ghasemi^a ; Deepti Yandhuri^b ; Suman S. Thakur^b ; Vani Brahmachari^a ; ^{vani.brahmachari@gmail.com}

关键词：Human PRE-TRE ; MLL ; Regulation ; Polycomb and trithorax ; Chromatin interaction ; Genetic interaction

刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

出版年：2017

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