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内部出版物
CNKI学位论文(43)
知网期刊论文(22)
在“
Elsevier电子期刊
”中,
命中:
145
条,耗时:小于0.01 秒
在所有数据库中总计命中:
65
条
1.
Transcriptional regulation of
microsomal
prostaglandin
E
synthase
1
by the proto-oncogene, c-myc, in the pathogenesis of inflammation and cancer
作者:
M. Ramanan
1
;
meera.ramanan79@gmail.com
;
V.S. Pilli
1
;
G.K. Aradhyam
agk@iitm.ac.in
;
M. Doble
;
mukeshd@iitm.ac.in
关键词:
Cancer
;
Inflammation
;
Prostaglandin
s
;
Transcription factor
;
c-myc
;
mPGES1
刊名:Biochemical and Biophysical Research Communications
出版年:20
1
7
2.
Identification of novel
microsomal
prostaglandin
E
2
synthase
-
1
(
mPGES
-
1
) lead inhibitors from Fragment Virtual Screening
作者:
Gianluigi Lauro
a
;
Michele Manfra
b
;
Silvana Pedatella
e
;
Katrin Fischer
d
;
Vincenza Cantone
a
;
d
;
Stefania Terracciano
a
;
Alessia Bertamino
a
;
Carmine Ostacolo
c
;
Isabel Gomez-Monterrey
c
;
Mauro De Nisco
b
;
Raffaele Riccio
a
;
Ettore Novellino
c
;
Oliver Werz
d
;
Pietro Campiglia
a
;
pcampiglia@unisa.it
;
Giuseppe Bifulco
a
;
bifulco@unisa.it
关键词:
Molecular docking
;
Cancer
;
Inflammation
;
mPGES
-
1
inhibitors
;
Virtual screening
刊名:European Journal of Medicinal Chemistry
出版年:20
1
7
3.
Dietary hydroxytyrosol and hydroxytyrosyl acetate supplementation prevent pristane-induced systemic lupus erythematous in mice
作者:
Marina Aparicio-Soto
a
;
Marina Sá
;
nchez-Hidalgo
a
;
Ana Cá
;
rdeno
a
;
Alejandro Gonzá
;
lez-Benjumea
b
;
José
;
G. Ferná
;
ndez-Bolañ
;
os
b
;
Catalina Alarcó
;
n-de-la-Lastra
a
;
calarcon@us.es
关键词:
ERK
;
extracellular signal-regulated kinase
;
EVOO
;
extra virgin olive oil
;
FCS
;
foetal calf serum
;
HO-
1
;
haem oxygenase-
1
;
HTy-Ac
;
hydroxytyrosyl acetate
;
HTy
;
hydroxytyrosol
;
iNOS
;
inducible nitric oxide
synthase
;
IKB-α
;
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-alpha
;
JNK
;
c-Jun N-terminal kinase
;
LPS
;
lipopolysaccharide
;
MAPK
;
mitogen-activated protein kinase
;
mPGES
-
1
;
microsomal
prostaglandin
E
synthase
-
1
;
MTT
;
3-(4
;
5-dimethylthiazol-2-yl)-2
;
5-diphenyltetraz
刊名:Journal of Functional Foods
出版年:20
1
7
4.
A positive feedback loop between progesterone and
microsomal
prostaglandin
E
synthase
-
1
-mediated PGE2 promotes production of both in mouse granulosa cells
作者:
Kazuhiro Tamura
a
;
hiro@toyaku.ac.jp" class="auth_mail" title="E-mail the corresponding author
;
Hiroaki Naraba
b
;
Takahiko Hara
c
;
Kota Nakamura
a
;
Mikihiro Yoshie
a
;
Hiroshi Kogo
a
;
Eiichi Tachikawa
a
关键词:
COX
;
cyclooxygenase
;
cPGES
;
cytosolic
prostaglandin
E
synthase
;
DMEM
;
Dulbecco&rsquo
;
s Modified Eagle&rsquo
;
s Medium
;
Egr-
1
;
early growth response factor
;
EGF
;
epidermal growth factor
;
EIA
;
enzyme immunoassay
;
FBS
;
fetal bovine serum
;
FSH
;
follicle-stimulating hormone
;
GC
;
granulosa cell
;
LH
;
luteinizing hormone
;
LPS
;
lipopolysaccharide
;
mPGES
;
microsomal
prostaglandin
E
synthase
;
P4
;
progesterone
;
PBS
;
phosphate-buffered saline
;
PGE
;
prostaglandin
E
;
PMA
;
phorbol
1
2-myristate-
1
3-acetate
;
PR
;
pr
刊名:
Prostaglandin
s and Other Lipid Mediators
出版年:20
1
6
5.
Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent
microsomal
prostaglandin
E
synthase
-
1
inhibitors
作者:
Steven L. Kuklish
a
;
Kuklish_Steven@lilly.com" class="auth_mail" title="E-mail the corresponding author
;
Stephen Antonysamy
b
;
Shobha N. Bhattachar
a
;
Srinivasan Chandrasekhar
a
;
&dagger
;
;
Matthew J. Fisher
a
;
Adrian J. Fretland
a
;
&Dagger
;
;
Karen Gooding
a
;
&dagger
;
;
Anita Harvey
a
;
&dagger
;
;
Norman E. Hughes
a
;
John G. Luz
b
;
Peter R. Manninen
a
;
James E. McGee
a
;
Antonio Navarro
a
;
Bryan H. Norman
a
;
Katherine M. Partridge
a
;
Steven J. Quimby
a
;
Matthew A. Schiffler
a
;
Ashley V. Sloan
a
;
Alan M. Warshawsky
a
;
Jeremy S. York
a
;
Xiao-Peng Yu
a
关键词:
mPGES
-
1
;
Prostaglandin
pathway
;
Dog bioavailability
;
Biomarker
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:20
1
6
6.
2,3-Dihydrobenzofuran privileged structures as new bioinspired lead compounds for the design of
mPGES
-
1
inhibitors
作者:
Simone Di Micco
a
;
Carmela Spatafora
b
;
Nunzio Cardullo
b
;
Raffaele Riccio
a
;
Katrin Fischer
c
;
Carlo Pergola
c
;
Andreas Koeberle
c
;
Oliver Werz
c
;
Malik Chalal
d
;
Dominique Vervandier-Fasseur
d
;
Corrado Tringali
b
;
Giuseppe Bifulco
a
;
bifulco@unisa.it" class="auth_mail" title="E-mail the corresponding author
关键词:
GSH
;
glutathione
;
MAPEG
;
membrane-associated proteins in eicosanoid and glutathione metabolism
;
MGST-
1
;
microsomal
glutathione transferase
1
;
mPGES
-
1
;
microsomal
prostaglandin
E2
synthase
-
1
;
COX
;
cyclooxygenase
;
PG
;
prostaglandin
刊名:Bioorganic & Medicinal Chemistry
出版年:20
1
6
7.
Discovery of 2-((2-chloro-6-fluorophenyl)amino)-N-(3-fluoro-5-(trifluoromethyl)phenyl)-
1
-methyl-7,8-dihydro-
1
H-[
1
,4]dioxino[2′,3′:3,4]benzo[
1
,2-d]imidazole-5-carboxamide as potent, selective and efficacious
microsomal
prostaglandin
E
2
synthase
-
1
(
mPGES
-
1
) inhibitor
作者:
Nagarajan Muthukaman
a
;
Sanjay Deshmukh
a
;
Neelam Sarode
a
;
Shital Tondlekar
a
;
Macchindra Tambe
a
;
Dnyandeo Pisal
a
;
Mahamadhanif Shaikh
a
;
Vidya G. Kattige
b
;
Srinivasa Honnegowda
b
;
Vikas Karande
b
;
Abhay Kulkarni
b
;
Satyawan B. Jadhav
c
;
Mahamad Yunnus A. Mahat
c
;
Girish S. Gudi
c
;
Neelima Khairatkar-Joshi
b
;
Laxmikant A. Gharat
a
;
Laxmikant.gharat@glenmarkpharma.com
关键词:
Rheumatoid arthritis
;
Benzimidazole
;
mPGES
-
1
inhibitor
;
PGE2
;
CSF concentration
;
Scaffold hopping
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:20
1
6
8.
Contribution de la
microsomal
prostaglandin
e E2
synthase
-
1
(
mPGES
-
1
) à l’inflammation de bas seuil associée à l’obésité et au diabète de type 2
作者:
C. Pierre
1
;
2
;
clement.pierre@biomeostasis.com" class="auth_mail" title="E-mail the corresponding author
;
C. Tardivel
2
;
R. Barbouche
2
;
B. Bariohay
1
;
S. Rami
2
;
J.-D. Troadec
2
刊名:Nutrition Clinique et Métabolisme
出版年:20
1
6
9.
Low E-prostanoid 2 receptor levels and deficient induction of the IL-
1
β/IL-
1
type I receptor/COX-2 pathway: Vicious circle in patients with aspirin-exacerbated respiratory disease
作者:
Liliana Machado-Carvalho
;
MS
a
;
b
;
lsmachad@clinic.ub.es" class="auth_mail" title="E-mail the corresponding author
;
Margarita Martí
n ;
PhD
a
;
c
;
Rosa Torres
;
PhD
a
;
b
;
d
;
Marta Gabasa
;
PhD
a
;
b
;
Isam Alobid
;
MD
;
PhD
a
;
b
;
e
;
Joaquim Mullol
;
MD
;
PhD
a
;
b
;
e
;
Laura Pujols
;
PhD
a
;
b
;
Jordi Roca-Ferrer
;
PhD
a
;
b
;
&lowast
;
;
Cesar Picado
;
MD
;
FERS
;
PhD
a
;
b
;
f
;
&lowast
;
关键词:
Aspirin-exacerbated respiratory disease
;
COX-2
;
E-prostanoid 2 receptor
;
fibroblasts
;
IL-
1
β
;
IL-
1
receptor type I
;
microsomal
prostaglandin
E
synthase
1
;
nasal mucosa
;
nasal polyps
;
prostaglandin
E2
刊名:Journal of Allergy and Clinical Immunology
出版年:20
1
6
10.
BRP-
1
87: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly
作者:
Ulrike Garscha
a
;
1
;
ulrike.garscha@uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Susanna Voelker
a
;
1
;
susanna.voelker@gmx.de" class="auth_mail" title="E-mail the corresponding author
;
Simona Pace
a
;
simona.pace@uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Jana Gerstmeier
a
;
jana.gerstmeier@uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Besa Emini
a
;
eminibesa@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Stefanie Liening
a
;
stefanie.liening@uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Antonietta Rossi
b
;
antrossi@unina.it" class="auth_mail" title="E-mail the corresponding author
;
Christina Weinigel
c
;
christina.weinigel@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Silke Rummler
c
;
silke.rummler@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Ulrich S. Schubert
d
;
e
;
ulrich.schubert@uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Gerhard K.E. Scriba
a
;
gerhard.scriba@uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Erşan Ç
;
elikoğlu
f
;
ersancelikoglu@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Burcu Ç
;
alışkan
f
;
brcaliskan@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Erden Banoglu
f
;
banoglu@gazi.edu.tr" class="auth_mail" title="E-mail the corresponding author
;
Lidia Sautebin
b
;
sautebin@unina.it" class="auth_mail" title="E-mail the corresponding author
;
Oliver Werz
a
;
d
;
oliver.werz@uni-jena.de" class="auth_mail" title="E-mail the corresponding author
关键词:
5-LO
;
5-lipoxygenase
;
AA
;
arachidonic acid
;
COX
;
cyclooxygenase
;
cPLA2
;
cytosolic phospholipase A2
;
FLAP
;
5-lipoxygenase-activating protein
;
fMLP
;
N-formyl-methionyl-leucyl-phenylalanine
;
H(P)ETE
;
hydro(pero)oxyeicosatetraenoic acid
;
HHT
;
hydroxyheptadecatrienoic acid
;
IL
;
interleukin
;
LPS
;
lipopolysaccharide
;
LT
;
leukotriene
;
mPGES
-
1
;
microsomal
prostaglandin
E2
synthase
1
;
MPO
;
myeloperoxidase
;
PG
;
phosphate-buffered saline plus
1
;
mg/ml glucose
;
PGC
;
phosphate-buffered saline plus
1
刊名:Biochemical Pharmacology
出版年:20
1
6
1
2
3
4
5
6
7
8
9
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