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知网期刊论文(710)
在“
Elsevier电子期刊
”中,
命中:
391
条,耗时:小于0.01 秒
在所有数据库中总计命中:
1,005
条
1.
Feasibility of the functional expression of the human organic anion transporting polypeptide 1B1 (
OATP
1B1) and its genetic variant 521T/C in the mouse liver
作者:
Yoon-Jee Chae
a
;
Kyeong-Ryoon Lee
b
;
Jong-Hwa Lee
c
;
Wooin Lee
d
;
Dae-Duk Kim
d
;
Suk-Jae Chung
d
;
sukjae@snu.ac.kr
;
Han-Joo Maeng
e
;
hjmaeng@gachon.ac.kr
关键词:
ALP
;
alkaline phosphatase
;
ALT
;
alanine aminotransferase
;
AST
;
aspartate aminotransferase
;
AUC
;
the area under the plasma concentration-time curve
;
CLapp
;
hep
;
hepatic uptake clearance
;
h
OATP
1B1
;
human organic anion transporting polypeptide 1B1
;
HGD
;
hydrodynamic gene delivery
;
HMG-CoA
;
3-hydroxy-3-methylglutaryl
;
IS
;
internal standard
;
LC-MS
;
liquid chromatography-mass spectrometry
;
m
OATP
s
;
mouse organic anion transporting polypeptides
;
RT-PCR
;
reverse transcription-polymerase chain reaction
;
S
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
2.
Selective cytotoxicity of microcystins LR, LW and LF in rat astrocytes
作者:
Klara Bulc Rozman
a
;
klara.bulc@rozman.si
;
Damijana Mojca Jurič
b
;
damijana-mojca.juric@mf.uni-lj.si
;
Du&scaron
;
an &Scaron
;
uput
a
;
dusan.suput@mf.uni-lj.si
关键词:
Microcystin
;
Cytotoxicity
;
Astrocytes
;
Oatp
;
Cytoskeleton
刊名:Toxicology Letters
出版年:2017
3.
Rapid isolation of peptidic inhibitors of the solute carrier family transporters
OATP
1B1 and OATP1B3 by cell-based phage display selections
作者:
Yuko Arita
a
;
Samantha Allen
b
;
Gang Chen
a
;
Wei Zhang
b
;
Ying Wang
b
;
Albert J. Owen
b
;
Patrick Dentinger
b
;
Sachdev S. Sidhu
a
;
sachdev.sidhu@utoronto.ca" class="auth_mail" title="E-mail the corresponding author
关键词:
Organic anion-transporting polypeptides
;
OATP
1B1
;
OATP
1B3
;
Phage-display
;
Peptide inhibitor
刊名:Biochemical and Biophysical Research Communications
出版年:2016
4.
Appropriate risk criteria for
OATP
inhibition at the drug discovery stage based on the clinical relevancy between OATP inhibitors and drug-induced adverse effect
作者:
Masanori Nakakariya
;
masanori.nakakariya@takeda.com" class="auth_mail" title="E-mail the corresponding author
;
Akihiko Goto
;
Nobuyuki Amano
关键词:
OATP
;
Rhabdomyolysis
;
Jaundice
;
Statin
;
Drug&ndash
;
drug interaction
;
Hyperbilirubinemia
;
Drug discovery
刊名:Drug Metabolism and Pharmacokinetics
出版年:2016
5.
Oral administration of nano-titanium dioxide particle disrupts hepatic metabolic functions in a mouse model
作者:
Julin Yang
a
;
Min Luo
b
;
Zhen Tan
b
;
Manyun Dai
b
;
Minzhu Xie
b
;
Jiao Lin
b
;
Huiying Hua
b
;
Qing Ma
b
;
Jinshun Zhao
b
;
Aiming Liu
b
;
liuaiming@nbu.edu.cn
关键词:
ALP
;
alkaline phosphatase
;
ALT
;
alanine aminotransferase
;
AST
;
aspartate aminotransferase
;
BUN
;
blood urea nitrogen
;
CYP
;
cytochrome P450
;
DBIL
;
direct bilirubin
;
GAPDH
;
glyceraldehyde 3-phosphate dehydrogenase
;
IBIL
;
indirect bilirubin
;
IL-6
;
interleukin 6
;
LDH
;
lactate dehydrogenase
;
Mrp
;
multidrug resistance-related protein
;
OATP
;
bile salt export pump
;
OSTB
;
organic solute-transporter-β
;
Q-PCR
;
Quantitative polymerase chain reaction
;
TBA
;
total bile acid
;
TiO2 NP
;
TiO2 nano-particle
;
TNFα
;
t
刊名:Environmental Toxicology and Pharmacology
出版年:2017
6.
Effects of microcystin-LR and cylindrospermopsin on plant-soil systems: A review of their relevance for agricultural plant quality and public health
作者:
J. Machado
a
;
A. Campos
a
;
V. Vasconcelos
a
;
b
;
M. Freitas
a
;
c
;
maf@ess.ipp.pt
关键词:
Adda
;
3-amino-9-methoxy-2
6 ;
8-trimethyl-10-phenyldeca-4
;
6-dienoic acid
;
APX
;
ascorbate peroxidase
;
CAT
;
catalase
;
CYN
;
cylindrospermopsin
;
Fv/Fm
;
chlorophyll fluorescence
;
GPX
;
glutathione peroxidase
;
GR
;
glutathione reductase
;
GSH
;
reduced glutathione
;
GST
;
glutathione-S-transferase
;
IARC
;
International Agency for Research on Cancer
;
MC(s)
;
Microcystin(s)
;
MC-LR
;
Microcystin-LR
;
Mdha
;
N-methyldehydroalanine
;
OATP
;
organic-anion transporting polypeptides
;
OECD
;
Organization for Economic Co-opera
刊名:Environmental Research
出版年:2017
7.
Rosuvastatin safety: An experimental study of myotoxic effects and mitochondrial alterations in rats
作者:
Samar O. El-Ganainy
a
;
samarossama@hotmail.com
;
samar.elganainy@pua.edu.eg
;
Ahmed El-Mallah
a
;
Dina Abdallah
b
;
Mahmoud M. Khattab
c
;
Mahmoud M. Mohy El-Din
a
;
Aiman S. El-Khatib
c
关键词:
OATP
;
Organic anion transporting polypeptide
;
CK
;
Creatine Kinase
;
LDH
;
lactate dehydrogenase enzyme
刊名:Toxicology Letters
出版年:2017
8.
Design, synthesis, in vitro characterization and preliminary imaging studies on fluorinated bile acid derivatives as PET tracers to study hepatic transporters
作者:
Andrea Testa
a
;
Sergio Dall&rsquo
;
Angelo
a
;
Marco Mingarelli
a
;
Andrea Augello
a
;
Lutz Schweiger
a
;
Andy Welch
a
;
Charles S. Elmore
b
;
Pradeep Sharma
c
;
Pradeep.Sharma@astrazeneca.com
;
Matteo Zanda
a
;
d
;
m.zanda@abdn.ac.uk
关键词:
Fluorine
;
Bile acids
;
Liver transporters
;
PET imaging
;
Tritium
;
Preclinical study
;
Click chemistry
;
Clearance
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
9.
Potential of prostaglandin transporter
OATP
2A1/SLCO2A1 as a target of novel anti-inflammatory drug
作者:
Hiroaki Shimada
1
;
2
;
Takeo Nakanishi
1
;
Yoshinobu Nakamura
1
;
Masahiro Iwaki
2
;
Ikumi Tamai
1
刊名:Drug Metabolism and Pharmacokinetics
出版年:2017
10.
The N-terminal region of organic anion transporting polypeptide 1B3 (
OATP
1B3) plays an essential role in regulating its plasma membrane trafficking
作者:
Se-Eun Chun
1
;
Nilay Thakkar
2
;
Ji Eun Park
1
;
Songhee Han
1
;
Hyunggu Hahn
1
;
Sang Hyun Maeng
1
;
Young-Ran Lim
3
;
Byung Woo Han
1
;
Wooin Lee
1
刊名:Drug Metabolism and Pharmacokinetics
出版年:2017
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