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内部出版物
在“
Elsevier电子期刊
”中,
命中:
71
条,耗时:0.0299814 秒
1.
Effects of frequently used pharmaceutical excipients on the
organic
cation
transporters
1-3 and peptide
transporters
1/2 stably expressed in MDCKII cells
作者:
Marcus Otter
;
Stefan Oswald
;
Werner Siegmund
;
Markus Keiser
;
markus.keiser@uni-greifswald.de
关键词:
Pharmaceutical excipients
;
Solubilizing agents
;
Drug transporter
;
Uptake transport
;
Organic
cation
transporter (OCT)
;
Peptide transporter (PEPT)
;
Polyethylene glycol (PEG)
;
Hydroxypropyl-β-cyclodextrin
;
Solutol HS 15 (macrogol 15 hydroxystearate
;
polyoxyl 15 hydroxystearate)
;
Cremophor
;
Tween (polysorbate)
;
Kolliphor (poloxamer)
;
MDCK cells
;
In vitro
;
Cell model
;
Competition assay
;
Inhibition assay
刊名:European Journal of Pharmaceutics and Biopharmaceutics
出版年:2017
2.
Organic
cation
rhodamines for screening
organic
cation
transporters
in early stages of drug development
作者:
Malachy C. Ugwu
a
;
b
;
1
;
Angus Oli
a
;
b
;
1
;
Charles O. Esimone
b
;
Remigius U. Agu
a
;
Remigius.agu@dal.ca" class="auth_mail" title="E-mail the corresponding author
关键词:
Organic
cation
transporters
(
OCT1
&
ndash
;
3)
;
Carnitine/
organic
cation
transporter (OCTN1
;
OCTN2)
;
Rhodamines
;
Calu-3 cells
;
Fluorescence
刊名:Journal of Pharmacological and Toxicological Methods
出版年:2016
3.
Polyspecific
organic
cation
transporters
and their impact on drug intracellular levels and pharmacodynamics
作者:
David J. Wagner
davidwag@uw.edu" class="auth_mail" title="E-mail the corresponding author
;
Tao Hu
taohu85@uw.edu" class="auth_mail" title="E-mail the corresponding author
;
Joanne Wang
;
jowang@uw.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Intracellular drug concentration
;
Pharmacodynamics
;
OCT
;
MATE
;
PMAT
;
Drug transporter
刊名:Pharmacological Research
出版年:2016
4.
Organic
cation
transporter function in different in vitro models of human lung epithelium
作者:
Johanna J. Salomon
a
;
1
;
Julia C. Gausterer
a
;
Tohru Yahara
b
;
Ken-ichi Hosoya
b
;
Hanno Huwer
c
;
Marius Hittinger
d
;
Nicole Schneider-Daum
d
;
Claus-Michael Lehr
d
;
Carsten Ehrhardt
a
;
ehrhardc@tcd.ie" class="auth_mail" title="E-mail the corresponding author
关键词:
Lung epithelial cell lines
;
OCT1
;
OCT2
;
OCT3
;
Pulmonary drug disposition
刊名:European Journal of Pharmaceutical Sciences
出版年:2015
5.
Absorption of ipratropium and l-carnitine into the pulmonary circulation of the ex-vivo rat lung is driven by passive processes rather than active uptake by OCT/OCTN
transporters
作者:
Ghaith Al-Jayyoussi
a
;
Daniel F. Price
a
;
Katharina Kreitmeyr
a
;
John P. Keogh
b
;
Mathew W. Smith
a
;
Mark Gumbleton
a
;
Christopher J. Morris
c
;
christopher.j.morris@uea.ac.uk" class="auth_mail" title="E-mail the corresponding author
关键词:
Organic
cation
transporters
;
OCT1
;
OCT2
;
OCT3
;
OCTN
;
SLC22
;
Isolated perfused rat lung (IPRL)
;
Transporters
;
Lung
;
Pulmonary absorption
刊名:International Journal of Pharmaceutics
出版年:2015
6.
Enhanced antitumour drug delivery to cholangiocarcinoma through the apical sodium-dependent bile acid transporter (ASBT)
作者:
Elisa Lozano
a
;
Maria J. Monte
a
;
d
;
Oscar Briz
a
;
d
;
Angel Herná
;
ndez-Herná
;
ndez
b
;
Jesus M. Banales
c
;
d
;
Jose J.G. Marin
a
;
d
;
jjgmarin@usal.es" class="auth_mail" title="E-mail the corresponding author
;
Rocio I.R. Macias
a
;
d
关键词:
ASBT
;
apical sodium dependent bile acid transporter
;
CCA
;
cholangiocarcinoma
;
CGamF
;
cholylglycyl amidofluorescein
;
CK-7
;
cytokeratin-7
;
GAPDH
;
glyceraldehyde-3-phosphate dehydrogenase
;
GSTpi
;
placental isoform of glutathione S-transferase
;
HCC
;
hepatocellular carcinoma
;
MDR
;
multidrug resistance
;
OCT1
;
organic
cation
transporter 1
;
TAA
;
thioacetamide
;
TCA
;
taurocholic acid
;
UDCA
;
ursodeoxycholic acid
刊名:Journal of Controlled Release
出版年:2015
7.
Optimization of human nasal epithelium primary culture conditions for optimal proton oligopeptide and
organic
cation
transporters
expression in vitro
作者:
Di Shao
a
;
Emad Massoud
b
;
David Clarke
b
;
Elizabeth Cowley
c
;
Ken Renton
d
;
Remigius U. Agu
a
;
b
;
Remigius.agu@dal.ca
关键词:
Nasal epithelium
;
Peptide
transporters
;
Organic
cation
transporters
;
OCT1
-3
;
OCTN1
;
OCTN2
;
PEPT1
;
PEPT2
刊名:International Journal of Pharmaceutics
出版年:2013
8.
Morphine is a substrate of the
organic
cation
transporter
OCT1
and polymorphisms in OCT1 gene affect morphine pharmacokinetics after codeine administration
作者:
Mladen V. Tzvetkov
;
Joao N. dos Santos Pereira
;
Ingolf Meineke
;
Ali R. Saadatm
;
Julia C. Stingl
;
J¨¹rgen Brockm?ller
关键词:
Organic
cation
transporter
OCT1
;
Liver uptake
;
Polymorphisms
;
Drug&
ndash
;
drug interactions
;
Morphine
;
Codeine
;
Pharmacokinetics
刊名:Biochemical Pharmacology
出版年:2013
9.
Inhibition of human
organic
cation
transporters
by the alkaloids matrine and oxymatrine
作者:
Xiaolei Pan
;
Li Wang
;
Dirk Gr眉ndemann
;
Douglas H. Sweet
关键词:
Drug&
ndash
;
drug interaction
;
SLC22
;
Solute carrier
;
Uptake
transporters
;
Matrine (PubChem CID
;
91466)
;
Oxymatrine (PubChem CID
;
114850)
刊名:Fitoterapia
出版年:January, 2014
10.
Regulation of renal
organic
anion and
cation
transporters
by thymoquinone in cisplatin induced kidney injury
作者:
Ramazan Ulu
a
;
Ayhan Dogukan
a
;
Mehmet Tuzcu
b
;
Hasan Gencoglu
b
;
Mustafa Ulas
c
;
Necip İ
;
lhan
d
;
Irfana Muqbil
e
;
Ramzi M. Mohammad
f
;
Omer Kucuk
g
;
Kazim Sahin
h
;
nsahinkm@yahoo.com
关键词:
4-HNE
;
4-hydroxy-2-nonenal
;
ANOVA
;
one-way analysis of variance
;
HPLC
;
high-performance liquid chromatography
;
MDA
;
malondialdehyde
;
MRPs
;
multidrug resistance-associated proteins
;
OATs
;
organic
anion
transporters
;
OCTs
;
organic
cation
transporters
;
ROS
刊名:Food and Chemical Toxicology
出版年:2012
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