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在“Elsevier电子期刊”中，命中：113条，耗时：0.0149927 秒

在所有数据库中总计命中：1,964条

1.New peptide deformylase inhibitors design, synthesis and pharmacokinetic assessment

作者：Fengping Lv^a ; Chen Chen^a ; Yang Tang^a ; Jianhai Wei^a ; Tong Zhu^b ; ^{tongzhu@chem.ecnu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Wenhao Hu^a ; ^{whu@chem.ecnu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：PDF inhibitor ; Antibacterial drug ; Antibiotics resistance ; MRSA ; Docking study ; Amide bioisosteres

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

2.Sitagliptin vs. placebo for non-alcoholic fatty liver disease: A randomized controlled trial

作者：Jeffrey Cui¹ ; Len Philo² ; Phirum Nguyen¹ ; Heather Hofflich³ ; Carolyn Hernandez¹ ; Ricki Bettencourt¹ ; ⁴ ; Lisa Richards¹ ; ⁵ ; Joanie Salotti¹ ; ⁵ ; Archana Bhatt¹ ; Jonathan Hooker⁶ ; William Haufe⁶ ; Catherine Hooker⁶ ; David A. Brenner⁵ ; Claude B. Sirlin⁶ ; Rohit Loomba¹ ; ⁴ ; ⁵ ; ⁷ ; ^{roloomba@ucsd.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：NAFLD ; non-alcoholic fatty liver disease ; NASH ; non-alcoholic steatohepatitis ; DPP-4 ; dipeptidyl peptidase 4 ; GLP-1 ; glucagon-like peptide-1 ; GIP ; glucose-dependent insulinotropic polypeptide ; HbA1c ; hemoglobin A1c ; SREBP-1c ; sterol regulatory element bind protein-1c ; T2DM ; type 2 diabetes mellitus ; ALT ; alanine aminotransferase ; AST ; aspartate aminotransferase ; GGT ; gamma-glutamyl transpeptidase ; MR ; magnetic resonance ; MRI ; magnetic resonance imaging ; MRI-PDFF ; MRI-proton density-fat fraction

刊名：Journal of Hepatology

出版年：2016

3.MicroRNA expression profiling in peritoneal fibrosis

作者：Yoshiyuki Morishita^a ; ^{ymori@jichi.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Hiromichi Yoshizawa^b ; Minami Watanabe^b ; Reika Imai^b ; Toshimi Imai^b ; Ichiro Hirahara^b ; Tetsu Akimoto^b ; Susumu Ookawara^a ; Shigeaki Muto^b ; Daisuke Nagata^b

关键词：α-SMA ; α-smooth muscle actin ; DAPI ; 4&prime ; 6-diamidino-2-phenylindole ; FGF ; fibroblast growth factor ; FSP-1 ; fibroblast-specific protein-1 ; MGO ; methylglyoxal ; miRNA ; microRNA ; PD ; peritoneal dialysis ; PDF ; peritoneal dialysis fluid ; PET ; peritoneal equilibrium test ; PF ; peritoneal fibrosis ; PPAR-α ; peroxisome proliferator&ndash ; activated receptor-α ; qRT-PCR ; real-time reverse-transcription polymerase chain reaction ; siRNA ; small interfering RNA ; TGF-β1 ; transforming growth factor-β1 ; VEGF ; va

刊名：Translational Research

出版年：2016

4.Stabilization of G-quadruplex DNA and inhibition of Bcl-2 expression by a pyridostatin analog

作者：Yun Feng^a ; ^{fjfengyun@sohu.com" class="auth_mail" title="E-mail the corresponding author} ; Dazhang Yang^a ; Hongbo Chen^b ; Wenli Cheng^c ; ^{chengwenli2013@163.com" class="auth_mail" title="E-mail the corresponding author} ; Lixia Wang^b ; Hongxia Sun^b ; ^{hongxsun@iccas.ac.cn" class="auth_mail" title="E-mail the corresponding author} ; Yalin Tang^b ; ^{tangyl@iccas.ac.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Bcl-2 gene ; P1 promoter ; G-quadruplex ; Pyridostatin analog ; Transcription

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

5.Identification of novel aminopiperidine derivatives for antibacterial activity against Gram-positive bacteria

作者：Hee-Yeol Lee ; Kyung-Mi An ; Juyoung Jung ; Je-Min Koo ; Jeong-Geun Kim ; Jong-Min Yoon ; Myong-Jae Lee ; HyeonSoo Jang ; Hong-Sub Lee ; Soobong Park ; Jae-Hoon Kang ; ^{jhkang@ildong.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Peptide deformylase ; Antibacterial ; Gram-positive ; Resistant ; Aminopiperidine

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

6.Influence of factor 5 rs6025 and factor 2 rs1799963 mutation on inhibitor development in patients with hemophilia A - an Israeli-German multicenter database study

作者：Gili Kenet^a ; Christoph Bidlingmaier^b ; Nadja Bogdanova^c ; Carmen Escuriola Ettingshausen^d ; Neil Goldenberg^e ; Sven Gutsche^f ; Susan Halimeh^g ; Susanne Holzhauer^h ; Karin Kurnik^b ; Verena Limpergerⁱ ; Ralf Junkerⁱ ; Ulrike Nowak-Gö ; ttl^j ; ^{leagottl@uksh.de" class="auth_mail}

关键词：BU ; Bethesda units ; ED ; exposure days ; F2 ; Factor 2 rs1799963 ; F5 ; Factor 5 rs6025 ; FVIII ; Factor VIII ; F8 ; Factor 8 genotypes ; HA ; hemophilia A ; HRI ; high-titer inhibitor ; HR/CI ; hazard ratio/confidence interval ; ICH ; intracranial hemorrhage ; IFS ; inhibitor-free survival ; IQR ; Interquartile range ; IT ; thrombophilic risk factor ; OR/CI ; Odds ratio/confidence interval ; PUP ; previously untreated patient ; pdFVIII ; plasma-derived factor VIII product ; rFVIII ; recombinant FVIII product

刊名：Thrombosis Research

出版年：April, 2014

7.N-Acyl-phosphoramidates as potential novel form of gemcitabine prodrugs

作者：Janina Baraniak^&dagger ; ; Aleksandra Pietkiewicz ; Renata Kaczmarek ; Ewa Radzikowska ; Katarzyna Kulik ; Karolina Krolewska ; Marcin Cieslak ; Agnieszka Krakowiak ; Barbara Nawrot ; ^{bnawrot@cbmm.lodz.pl" class="auth_mail}

关键词：Gemcitabine ; Prodrug ; Cytotoxicity ; Anticancer therapy ; DNA polymerase inhibitor

刊名：Bioorganic and Medicinal Chemistry

出版年：1 April, 2014

8.Upregulation of HIF-2伪 induced by sorafenib contributes to the resistance by activating the TGF-伪/EGFR pathway in hepatocellular carcinoma cells

作者：Dali Zhao^a ; Bo Zhai^a ; Changjun He^b ; Gang Tan^a ; Xian Jiang^a ; Shangha Pan^a ; Xuesong Dong^a ; Zheng Wei^a ; Lixin Ma^a ; Haiquan Qiao^a ; Hongchi Jiang^a ; Xueying Sun^a ; ^{kevsun88@hotmail.com" class="auth_mail} ; ^{k.sun@auckland.ac.nz" class="auth_mail}

关键词：ANOVA ; analysis of variance ; ARNT ; aryl hydrocarbon receptor nuclear translocator ; CCK-8 ; Cell Counting Kit-8 ; CHX ; cycloheximide ; DMEM ; Dulbecco's modified Eagle's medium ; DMSO ; dimethyl sulfoxide ; EGFR ; epidermal growth factor receptor ; ERK ; extracellular signal-regulated kinase ; FITC ; fluorescein isothiocyanate ; HCC ; hepatocellular carcinoma ; HIF-1伪 ; hypoxia-inducible factor-1伪 ; HIF-2伪 ; hypoxia-inducible factor-2伪 ; MAPK ; mitogen-activated protein kinase ; PDFR ; platelet-derived growth fact

刊名：Cellular Signalling

出版年：May, 2014

9.Caffeic acid phenethyl ester (CAPE), an active component of propolis, inhibits Helicobacter pylori peptide deformylase activity

作者：Kunqiang Cui^a ; ¹ ; Weiqiang Lu^a ; ¹ ; Lili Zhu^a ; ¹ ; Xu Shen^a ; ^b ; Jin Huang^a ; ^{huangjin@ecust.edu.cn}

关键词：CAPE ; caffeic acid phenethyl ester ; PDF ; peptide deformylase ; HpPDF ; Helicobacter pylori PDF ; PDIs ; peptide deformylase inhibitors ; FDH ; formate dehydrogenase ; f-MAS ; N-formyl-Met-Ala-Ser

刊名：Biochemical and Biophysical Research Communications

出版年：2013

10.Acylprolinamides: A new class of peptide deformylase inhibitors with in vivo antibacterial activity

作者：Jeffrey M. Axten^a ; ^{jeffrey.m.axten@gsk.com} ; Jesú ; s R. Medina^a ; Charles W. Blackledge^a ; Cé ; line Duquenne^a ; Seth W. Grant^a ; Mark A. Bobko^a ; Tony Peng^a ; William H. Miller^a ; Theresa Pinckney^a ; Timothy F. Gallagher^a ; Swarupa Kulkarni^a ; Thomas Lewandowski^a ; Glenn S. Van Aller^a ; Rimma Zonis^a ; Paris Ward^b ; Nino Campobasso^b

关键词：Peptide deformylase ; PDF inhibitor ; Antibacterial ; Antibiotic

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2012

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