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在“Elsevier电子期刊”中，命中：440条，耗时：0.02898 秒

在所有数据库中总计命中：1,474条

1.Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity

作者：Michela De Bellis^a ; Roberta Carbonara^a ; Julien Roussel^a ; Alessandro Farinato^a ; Ada Massari^a ; Sabata Pierno^a ; Marilena Muraglia^b ; Filomena Corbo^b ; Carlo Franchini^b ; Maria Rosaria Carratù ; ^c ; Annamaria De Luca^a ; Diana Conte Camerino^a ; Jean-Franç ; ois Desaphy^c ; ^{jeanfrancois.desaphy@uniba.it}

关键词：Sodium channel ; Use-dependence ; Myotonia ; Membrane hyperexcitability ; Tocainide derivative ; Mexiletine

刊名：Neuropharmacology

出版年：2017

2.High-Throughput Screening of Nav1.7 Sodium Channel Blockers in an Automated Patch Clamp Assay

刊名：Biophysical Journal

出版年：2017

3.Modeling interactions between blocking and permeant cations in the NavMs channel

作者：Vyacheslav S. Korkosh^a ; Boris S. Zhorov^a ; ^b ; Denis B. Tikhonov^a ; ^{denistikhonov2002@yahoo.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Sodium channels ; Ion channel block ; Mechanism of action ; Local anesthetics

刊名：European Journal of Pharmacology

出版年：2016

4.Gene expression profiling of calcium-channel antagonists in the heart of hypertensive and normotensive rats reveals class specific effects

作者：Carolin Zwadlo ; Dr.^a ; ^{Zwadlo.Carolin@mh-hannover.de} ; Jü ; rgen Borlak ; Dr.^b ; ^{Borlak.Juergen@mh-hannover.de} (Prof.)

关键词：AV ; atrioventricular ; CCB ; Calcium channel blockers ; Na+-K+-ATPase ; sodium-potassium-exchanger ; NCX-1 ; sodium-calcium-exchanger ; PMCA1 ; plasma membrane Ca2 ; +-ATPase isoform 1 ; RyR ; ryanodine receptor isoform ; SA ; sinoatrial ; SERCA2b ; sarcoplasmic reticulum ATPase isoform 2b

刊名：Vascular Pharmacology

出版年：2016

5.How to determine cardiac ion channels targeted by drugs using the isolated rabbit ventricular wedge model

作者：Guizhi Liu^a ; ^b ; Tong Liu^c ; Daniel Cohen^b ; Tengxian Liu^b ; Gan-Xin Yan^b ; ^d ; ^{yanganxin@comcast.net" class="auth_mail" title="E-mail the corresponding author}

关键词：Rabbit ventricular wedge assay ; Drug safety ; Tp-e/QT ratio ; IKr blocker ; QT-BCL slope ; Positive staircase response of contractility ; Use-dependency ; Calcium channel blocker ; Potassium channel activator

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

6.PITX2 Modulates Atrial Membrane Potential and the Antiarrhythmic Effects of Sodium-Channel Blockers

作者：Fahima Syeda ; PhD^a ; Andrew P. Holmes ; PhD^a ; Ting Y. Yu ; PhD^a ; ^b ; Samantha Tull ; PhD^a ; Stefan Michael Kuhlmann ; BSc^a ; Davor Pavlovic ; DPhil^a ; Daniel Betney ; BMedSc ; MBBS^a ; Genna Riley ; DPhil^a ; Jan P. Kucera ; MD^c ; Florian Jousset ; PhD^c ; Joris R. de Groot ; MD^d ; Stephan Rohr ; MD^c ; Nigel A. Brown ; PhD^e ; Larissa Fabritz ; MD^a ; ^f ; ^g ; ^h ; Paulus Kirchhof ; MD^a ; ^f ; ^g ; ^h ; ⁱ ; ^{p.kirchhof@bham.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：antiarrhythmic drugs ; atrial fibrillation ; drug targets ; electrophysiology ; personalized medicine ; rhythm control

刊名：Journal of the American College of Cardiology

出版年：2016

7.Electrical stimulation of adipose-derived mesenchymal stem cells in conductive scaffolds and the roles of voltage-gated ion channels

作者：Jieyu Zhang^a ; ^{zhangjieyu@u.nus.edu" class="auth_mail" title="E-mail the corresponding author} ; Min Li^b ; ^{chelim@nus.edu.sg" class="auth_mail" title="E-mail the corresponding author} ; En-Tang Kang^a ; ^b ; ^{cheket@nus.edu.sg" class="auth_mail" title="E-mail the corresponding author} ; Koon Gee Neoh^a ; ^b ; ^{chenkg@nus.edu.sg" class="auth_mail" title="E-mail the corresponding author}

关键词：Electrical stimulation ; Polypyrrole ; Adipose-derived mesenchymal stem cells ; Polycaprolactone scaffold ; Voltage-gated ion channels

刊名：Acta Biomaterialia

出版年：2016

8.Membrane-binding properties of gating modifier and pore-blocking toxins: Membrane interaction is not a prerequisite for modification of channel gating

作者：Evelyne Deplazes^a ; ^b ; ¹ ; ^{e.deplazes@uq.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Só ; nia Troeira Henriques^a ; ¹ ; Jennifer J. Smith^a ; Glenn F. King^a ; David J. Craik^a ; Alan E. Mark^b ; Christina I. Schroeder^a ; ^{c.schroeder@imb.uq.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：CaV ; Voltage-gated calcium channel ; GMs ; Gating modifier ; gating-modifying peptide ; Hd1a ; μ-TRTX-Hd1a ; KV ; Voltage-gated potassium channel ; LUV ; Large unilamellar vesicle ; NaV ; Voltage-gated sodium channel ; PBs ; Pore blocker ; pore blocking peptide ; POPC ; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine ; POPS ; 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine ; ProTx-I ; Protoxin1 ; β-theraphotoxin-Tp1a ; VGICs ; Voltage-gated ion channels ; VSDs ; Voltage-sensing domains ; SASA ; Solvent accessible surf

刊名：Biochimica et Biophysica Acta (BBA)-Biomembranes

出版年：2016

9.Synthesis and evaluation of novel α-aminoamides with substituted benzene scaffold for the treatment of neuropathic pain

作者：Hao-Tian Li ; Shi-Yong Fan ; Zhi-Ping Li ; Fang-Lin Yu ; Xiao-Qin Hu ; Jing-Chao Cheng ; Ping Zhang ; Bo-Hua Zhong ; ^{bohuazhong@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Wei-Guo Shi ; ^{shiwg1988@126.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Neuropathic pain ; α-Aminoamide derivatives ; Voltage-gated sodium channel blockers ; Theory of bioisosterism

刊名：Chinese Chemical Letters

出版年：2016

10.Local-anesthetic like inhibition of the cardiac sodium channel Nav1.5 α-subunit by 5-HT₃ receptor antagonists

作者：Mariet P. van't Klooster^a ; ¹ ; Nilufar Foadi^a ; ¹ ; Axel Hage^a ; Carsten Stoetzer^a ; Florian Wegner^b ; Mirjam Eberhardt^a ; Andreas Leffler^a ; ^{leffler.andreas@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author}

关键词：5-HT3 receptor antagonist ; Tropisetron ; Granisetron ; Ondansetron ; Nav1.5 ; Local anesthetic

刊名：European Journal of Pharmacology

出版年：2016

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