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在“Elsevier电子期刊”中，命中：378条，耗时：0.0749916 秒

在所有数据库中总计命中：1,260条

1.A combination of sorafenib and SC-43 is a synergistic SHP-1 agonist duo to advance hepatocellular carcinoma therapy

作者：Tzu-I Chao^a ; ¹ ; Wei-Tien Tai^a ; ^b ; ¹ ; Man-Hsin Hung^c ; ^d ; ¹ ; Ming-Hsien Tsai^a ; Min-Hsuan Chen^a ; Mao-Ju Chang^a ; Chung-Wai Shiau^e ; Kuen-Feng Chen^a ; ^b ; ^{kfchen1970@ntu.edu.tw" class="auth_mail" title="E-mail the corresponding author}

关键词：HCC ; hepatocellular carcinoma ; SHP-1 ; Src homology region 2 domain containing phosphatase 1 ; STAT3 ; signal transducer and activator of transcription 3 ; p-STAT3 ; phosphorylated STAT3 ; Raf ; rapidly accelerated fibrosarcoma ; VEGFR ; vascular endothelial growth factor receptor ; PDGFR ; platelet-derived growth factor receptor ; PTP ; protein tyrosine phosphatase ; SH2 ; Src homology region 2 ; DMSO ; dimethyl sulfoxide ; DMEM ; Dulbecco's modified Eagles' medium ; PARP ; Poly (ADP-ribose) polymerase ; Mcl-1 ; myel

刊名：Cancer Letters

出版年：2016

2.Cool-temperature-mediated activation of phospholipase C-γ₂ in the human hereditary disease PLAID

作者：Anja Schade^a ; Claudia Walliser^a ; Martin Wist^a ; Jennifer Haas^a ; Petra Vatter^a ; Johann M. Kraus^b ; Davide Filingeri^c ; ¹ ; George Havenith^c ; Hans A. Kestler^b ; Joshua D. Milner^d ; Peter Gierschik^a ; ^{peter.gierschik@uni-ulm.de" class="auth_mail" title="E-mail the corresponding author}

关键词：PLC ; inositol-phospholipid-specific phospholipase C ; SH2 ; Src homology domain 2 ; SH3 ; Src homology domain 3 ; PH ; pleckstrin homology domain ; spPH ; split PH domain ; PCI ; phospholipase C inhibitor peptide ; Rac ; Ras-related C3 botulinum toxin substrate ; BCR ; B cell receptor ; SA ; specific array ; PLAID ; PLCγ2-associated antibody deficiency and immune dysregulation ; TRP ; transient receptor potential ; PtdIns ; phosphatidylinositol ; PtdIns(4)P ; phosphatidylinositol 4-phosphate ; PtdIns(4 ; 5)P2 ; phosphatidy

刊名：Cellular Signalling

出版年：2016

3.Simultaneous regulation of apoptotic gene silencing and angiogenic gene expression for myocardial infarction therapy: Single-carrier delivery of SHP-1 siRNA and VEGF-expressing pDNA

作者：Dongkyu Kim^a ; ^b ; ¹ ; Sook Hee Ku^a ; ¹ ; Hyosuk Kim^a ; ^c ; Ji Hoon Jeong^a ; ^d ; Minhyung Lee^e ; Ick Chan Kwon^a ; ^d ; Donghoon Choi^b ; ^{cdhlyj@yuhs.ac} ; Sun Hwa Kim^a ; ^{sunkim@kist.re.kr}

关键词：SHP-1 siRNA ; VEGF plasmid DNA ; Myocardial ischemia-reperfusion injury ; Deoxycholic acid-modified polyethylenimine

刊名：Journal of Controlled Release

出版年：2016

4.Dovitinib Acts As a Novel Radiosensitizer in Hepatocellular Carcinoma by Targeting SHP-1/STAT3 Signaling

作者：Chao-Yuan Huang ; MD ; PhD^&lowast ; ; ^&dagger ; ; Wei-Tien Tai ; PhD^&Dagger ; ; ^§ ; ; Szu-Yuan Wu ; MD^‖ ; ^¶ ; ; ^# ; ^&lowast ; &lowast ; ; Chih-Ting Shih ; MS^&Dagger ; ; Min-Hsuan Chen ; MS^&Dagger ; ; Ming-Hsien Tsai^&Dagger ; ; Chiung-Wen Kuo ; PhD^&dagger ; &dagger ; ; Chung-Wai Shiau ; PhD^&Dagger ; &Dagger ; ; Man-Hsin Hung ; MD^§ ; § ; ; ^‖‖ ; ^¶ ; ¶ ; ; ^## ; ^{cindybeaty@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Kuen-Feng Chen ; MD ; PhD^&Dagger ; ; ^§ ; ; ^{kfchen1970@ntu.edu.tw" class="auth_mail" title="E-mail the corresponding author}

刊名：International Journal of Radiation Oncology*Biology*Physics

出版年：2016

5.The alpha secretase ADAM10: A metalloprotease with multiple functions in the brain

作者：Paul Saftig^a ; ^{psaftig@biochem.uni-kiel.de" class="auth_mail" title="E-mail the corresponding author} ; Stefan F. Lichtenthaler^b ; ^c ; ^{stefan.lichtenthaler@dzne.de" class="auth_mail" title="E-mail the corresponding author}

关键词：ADAM ; A Disintegrin And Metalloproteinase ; BACE ; β-site APP cleaving enzyme ; APP ; amyloid precursor protein ; AD ; Alzheimer disease ; RIP ; regulated intramembrane proteolysis ; PC ; prohormone convertase ; CNS ; central nervous system ; UTR ; untranslated region ; SIRT1 ; NAD-dependent deacytylase sirtuin-1 ; PC ; prohormone convertase ; ER ; endoplasmic reticulum ; SH3 ; Src homology 3-binding domain ; PACAP ; pituitary adenylate cyclase-activating polypeptide ; MAPK ; mitogen activated protein kinase ; SAP97 ; syna

刊名：Progress in Neurobiology

出版年：2015

6.The zinc-binding region of IL-2 inducible T cell kinase (Itk) is required for interaction with G¦Á13 and activation of serum response factor

作者：Weishan Huang^a ; ^b ; J. Luis Morales^b ; Victor P. Gazivoda^a ; Jianbin Lai^c ; Qian Qi^a ; ^b ; ¹ ; Avery August^a ; ^b ; ^{averyaugust@cornell.edu}

关键词：G-protein ; guanine nucleotide binding protein ; GFP ; green fluorescent protein ; Itk ; inducible T cell kinase ; PH ; pleckstrin homology domain ; PRR ; proline rich region ; TcR ; T cell receptor ; TH ; Tec homology domain ; SH2 ; Src homology domain 2 ; SH3 ; Src homo

刊名：The International Journal of Biochemistry and Cell Biology

出版年：2013

7.PLEKHG2/FLJ00018, a Rho family-specific guanine nucleotide exchange factor, is tyrosine phosphorylated via the EphB2/cSrc signaling pathway

作者：Katsuya Sato ; Takahiro Suzuki ; Yoshihiro Yamaguchi ; Yukio Kitade ; Takahiro Nagase ; Hiroshi Ueda

关键词：DH ; dbl homology ; DHR ; dock homology region ; DMEM ; Dulbecco's modified Eagle's medium ; Eph ; ephrin receptor ; FBS ; fetal bovine serum ; GAP ; GTPase activating protein ; G-protein ; guanosine triphosphate-binding protein ; GPCR ; heterotrimeric G-protein-coupled receptor ; PBS ; phosphate-buffered saline ; PDZ ; post synaptic density protein ; Drosophila disc large tumor suppressor and zonula occludens-1 protein ; PH ; pleckstrin homology ; Rho ; rho family small G-protein ; RhoGEF ; Rho-specific guanine nucleoti

刊名：Cellular Signalling

出版年：April, 2014

8.Inhibition of IL-6 family cytokines by SOCS3

作者：Jeffrey J. Babon^a ; ^b ; ^{babon@wehi.edu.au" class="auth_mail} ; Leila N. Varghese^a ; ^b ; Nicos A. Nicola^a ; ^b

关键词：JAKs ; Janus Kinases ; SOCS ; Suppressor of Cytokine Signalling ; STAT ; Signal Transducers and Activators of Transcription ; IL-6 ; interleukin-6 ; IL-10 ; interleukin-10 ; IL-11 ; interleukin-11 ; IL-27 ; interleukin-27 ; gp130 ; glycoprotein 130 ; OSM ; oncostatin M ; LIF ; leukemia inhibitory factor ; CNTF ; cillary neurotrophic factor ; CT-1 ; cardiotrophin 1 ; IL-6R伪 ; interleukin-6 receptor alpha-chain ; G-CSF ; granulocyte colony-stimulating factor ; KIR ; kinase inhibitory region ; SH2 ; Src homology 2 ; SHP2 ; SH2 do

刊名：Seminars in Immunology

出版年：February, 2014

9.Functional conservation of suppressors of cytokine signaling proteins between teleosts and mammals: Atlantic salmon SOCS1 binds to JAK/STAT family members and suppresses type I and II IFN signaling

作者：Astrid Skjesol^a ; ¹ ; Theresa Liebe^a ; ^b ; ¹ ; Dimitar B. Iliev^a ; Ernst I.S. Thomassen^a ; Linn Greiner Tollersrud^a ; Mehrdad Sobhkhez^a ; Lisbeth Lindenskov Joensen^a ; Christopher J. Secombes^c ; Jorunn B. Jø ; rgensen^a ; ^{jorunn.jorgensen@uit.no" class="auth_mail}

关键词：bp ; base pair ; JAK ; Janus kinase ; Tyk2 ; tyrosine kinase 2 ; IFN ; interferon ; JAB ; JAK-binding protein ; SH2 ; SRC-homology 2 ; ESS ; extended SH2 domain ; KIR ; kinase inhibitory region ; SOCS ; suppressors of cytokine signaling ; STAT ; signal transducers and activators of the transcription ; SSI ; STAT-induced STAT-inhibitor ; JH ; Janus homology ; ODNs ; oligodeoxynucleotides ; MOI ; multiplicity of infection ; ISGs ; interferon responsive genes ; ISRE ; interferon stimulated response element

刊名：Developmental and Comparative Immunology

出版年：July, 2014

10.Nintedanib (BIBF-1120) inhibits hepatocellular carcinoma growth independent of angiokinase activity

作者：Wei-Tien Tai¹ ; ² ; ^&dagger ; ; Chung-Wai Shiau³ ; ^&dagger ; ; Yong-Shi Li¹ ; ² ; Chun-Wei Chang¹ ; ² ; Jui-Wen Huang⁴ ; Ting-Ting Hsueh³ ; Hui-Chuan Yu¹ ; ² ; Kuen-Feng Chen¹ ; ² ; ^{kfchen1970@ntu.edu.tw" class="auth_mail}

关键词：HCC ; hepatocellular carcinoma ; Ab ; antibody ; IP ; immunoprecipitation ; p-STAT3 ; phosphorylated STAT3 ; PTPs ; protein tyrosine phosphatases ; SH2 ; Src homology region 2 ; SHP-1 ; SH2 domain-containing phosphatase 1 ; STAT3 ; signal transducer and activator of transcription 3 ; VEGF ; vascular endothelial growth factor receptor ; VEGFR ; vascular endothelial growth factor receptor ; WT ; wild type

刊名：Journal of Hepatology

出版年：July 2014

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