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在“Elsevier电子期刊”中，命中：11,366条，耗时：0.1619491 秒

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1.Structure-activity relationships of diverse xanthones against multidrug resistant human tumor cells

作者：Qiwen Wang^a ; Chenyao Ma^a ; Yun Ma^a ; Xiang Li^a ; ^c ; ^{lixiang_8182@163.com} ; Yong Chen^a ; ^{achenyongmail@163.com} ; Jianwei Chen^a ; ^b

关键词：Xanthone ; Cytotoxic activity ; Multidrug resistant ; Structure-activity relationships

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.Diversity selection, screening and quantitative structure-activity relationships of osmolyte-like additive effects on the thermal stability of a monoclonal antibody

作者：Olubukayo-Opeyemi Oyetayo^a ; ^{oyetayophdhbc@gmail.com} ; Oscar Mé ; ndez-Lucio^b ; Andreas Bender^b ; Hans Kiefer^a

关键词：mAb ; Monoclonal antibody ; MOE ; Molecular Operating Environment ; MDS ; Multi-dimensional scaling ; QSAR ; Quantitative structure&ndash ; activity relationship ; DSC ; Differential scanning calorimetry ; DSF ; Differential scanning fluorimetry ; DMSO ; Dimethyl sulfoxide ; NaOH ; Sodium hydroxide ; HCl ; Hydrochloric acid ; LOO-CV ; Leave-one-out cross-validation ; PCA ; Principal components analysis ; PLS ; Partial least squares ; TMAO ; Trimethylamine N-oxide ; Tm ; Melting temperature ; TS potency ; Thermal stabilization

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

3.Synthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent antimitotic agents

作者：Davide Carta^a ; Roberta Bortolozzi^b ; Mattia Sturlese^a ; Veronica Salmaso^a ; Ernest Hamel^c ; Giuseppe Basso^b ; Laura Calderan^a ; Luigi Quintieri^a ; Stefano Moro^a ; Giampietro Viola^b ; Maria Grazia Ferlin^a ; ^{mariagrazia.ferlin@unipd.it}

关键词：Microtubules ; Phenylpyrroloquinolinone ; Tubulin ; Apoptosis ; Molecular docking ; Structure-activity relationships

刊名：European Journal of Medicinal Chemistry

出版年：2017

4.The relationships between urban parks, residents' physical activity, and mental health benefits: A case study from Beijing, China

作者：Hongxiao Liu^a ; ^b ; Feng Li^a ; ^b ; ^{lifeng@rcees.ac.cn} ; Juanyong Li^c ; Yuyang Zhang^d

关键词：Green space ; Physical activity ; Mental health benefits ; Public health ; Active lifestyle

刊名：Journal of Environmental Management

出版年：2017

5.Antiproliferative activity and SARs of caffeic acid esters with mono-substituted phenylethanols moiety

作者：Jin Xie ; Fengzhi Yang ; Man Zhang ; Celine Lam ; Yixue Qiao ; Jia Xiao ; Dongdong Zhang ; Yuxuan Ge ; Lei Fu ; ^{leifu@sjtu.edu.cn} ; Dongsheng Xie ; ^{dshxie@sjtu.edu.cn}

关键词：Caffeic acid esters ; CAPE derivatives ; Antiproliferative activity ; Structure-activity relationships

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

6.Structure-activity relationships of cinnamaldehyde and eugenol derivatives against plant pathogenic fungi

作者：Yongjian Xie^a ; Qianqian Huang^a ; Zhunjing Wang^a ; Haiyan Cao^b ; Dayu Zhang^a ; ^{zhangdayu@zafu.edu.cn}

关键词：Antifungal activity ; Cinnamaldehyde derivatives ; Eugenol derivatives ; Rhizoctonia solani ; Fusarium oxysporum

刊名：Industrial Crops and Products

出版年：2017

7.Synthesis of novel 15-membered 8a-azahomoerythromycin A acylides: Consequences of structural modification at the C-3 and C-6 position on antibacterial activity

作者：Dražen Pavlović^a ; ^{drazenpavlovic@rcsi.ie} ; Scott Kimmins^b ; Stjepan Mutak^a

关键词：Macrolide antibiotics ; Macrolide resistance ; Acylides ; Structure-activity relationships ; Antibacterial activity ; Heck reaction

刊名：European Journal of Medicinal Chemistry

出版年：2017

8.Imidazopyridine-fused [1,3]-diazepinones part 2: Structure-activity relationships and antiproliferative activity against melanoma cells

作者：Virginie Bellet ; Laure Lichon ; Dominique P. Arama ; Audrey Gallud ; Vincent Lisowski ; Ludovic T. Maillard ; Marcel Garcia ; Jean Martinez ; Nicolas Masurier ; ^{nicolas.masurier@umontpellier.fr}

关键词：Imidazo[1 ; 2-a]pyridine ; Polyfused heterocycles ; Diazepinones ; Antitumor activity ; Melanoma

刊名：European Journal of Medicinal Chemistry

出版年：2017

9.Structure-activity relationships and optimization of acyclic acylphloroglucinol analogues as novel antimicrobial agents

作者：Haibo Tan^a ; ¹ ; Hongxin Liu^a ; ^b ; ¹ ; Liyun Zhao^a ; ^c ; Yao Yuan^a ; ^c ; Bailin Li^a ; ^c ; Yueming Jiang^a ; Liang Gong^a ; ^{lianggong@scbg.ac.cn} ; Shengxiang Qiu^a ; ^{sxqiu@scbg.ac.cn}

关键词：Anti-MRSA ; Acylphloroglucinol ; Mechanism ; Structure-activity relationship

刊名：European Journal of Medicinal Chemistry

出版年：2017

10.Discovery of biphenyl imidazole derivatives as potent antifungal agents: Design, synthesis, and structure-activity relationship studies

作者：Dongmei Zhao^a ; ^{medchemzhao@163.com} ; Shizhen Zhao^a ; Liyu Zhao^a ; Xiangqian Zhang^a ; Peng Wei^a ; Chunchi Liu^a ; Chenzhou Hao^a ; Bin Sun^c ; Xin Su^b ; ^{suxin1966@163.com} ; Maosheng Cheng^a

关键词：Antifungal activity ; CYP51 ; Structure-activity relationship ; Azole antifungals

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

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