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CNKI期刊论文0611(1)
在“
Elsevier电子期刊
”中,
命中:
272
条,耗时:小于0.01 秒
在所有数据库中总计命中:
1,203
条
1.
A triple exon-skipping luciferase reporter assay identifies a new
CLK
inhibitor pharmacophore
作者:
Yihui Shi
;
Jaehyeon Park
;
Chandraiah Lagisetti
;
Wei Zhou
;
Lidia C. Sambucetti
;
Thomas R. Webb
;
thomas.webb@sri.com
关键词:
CLK
;
cdc2-like kinase
;
MDM2
;
mouse double minute 2 homolog
;
Luc
;
luciferase
;
TEA
;
triethylamine
;
DIPEA
;
diisopropylethylamine
;
EtOAc
;
ethyl acetate
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
2.
Clk
1 deficiency promotes neuroinflammation and subsequent dopaminergic cell death through regulation of microglial metabolic reprogramming
作者:
Ruinan Gu
a
;
Fali Zhang
a
;
Gang Chen
b
;
Chaojun Han
a
;
Jay Liu
b
;
Zhaoxiang Ren
a
;
Yi Zhu
a
;
John L. Waddington
a
;
c
;
Long Tai Zheng
a
;
zhenglongtai@suda.edu.cn
;
Xuechu Zhen
a
;
xuechuzhen@suda.edu.cn
关键词:
Clk
1
;
Microglia
;
Glycolysis
;
MPTP
;
mTOR/HIF-1α
刊名:Brain, Behavior, and Immunity
出版年:2017
3.
Novel
CLK
1 inhibitors based on N-aryloxazol-2-amine skeleton - A possible way to dual VEGFR2 TK/CLK ligands
作者:
Miroslav Murá
;
r
a
;
Juraj Dobia&scaron
;
a
;
Peter &Scaron
;
ramel
a
;
c
;
Gabriela Addová
;
b
;
Gilles Hanquet
c
;
Andrej Bohá
;
č
a
;
d
;
andrej.bohac@fns.uniba.sk
关键词:
Dual
CLK
1/VEGFR2 kinase ligands
;
CDK9
;
GSK3
;
DYRK1A
;
GSK3α/β
;
Muti-targeted kinase inhibitors
刊名:European Journal of Medicinal Chemistry
出版年:2017
4.
Adipose Tissue
CLK
2 Promotes Energy Expenditure during High-Fat Diet Intermittent Fasting
作者:
Maximilian Hatting
1
;
2
;
Amy K. Rines
1
;
Chi Luo
1
;
Mitsuhisa Tabata
1
;
Kfir Sharabi
1
;
Jessica A. Hall
1
;
Francisco Verdeguer
1
;
Christian Trautwein
2
;
Pere Puigserver
1
;
3
;
pere_puigserver@dfci.harvard.edu
关键词:
CLK
2
;
intermittent fasting
;
brown fat
;
high-fat diet
;
diet-induced thermogenesis
;
refeeding
;
UCP1
;
p-CREB
;
PP2A
刊名:Cell Metabolism
出版年:2017
5.
Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor
作者:
Lyamin Z. Bendjeddou
a
;
b
;
Nadè
;
ge Loaë
;
c
a
;
Benoî
;
t Villiers
a
;
Eric Prina
c
;
Gerald F. Spä
;
th
c
;
Hervé
;
Galons
b
;
Laurent Meijer
a
;
meijer@manros-therapeutics.com
;
Nassima Oumata
a
;
oumata@manros-therapeutics.com
关键词:
Kinase inhibitor
;
Imidazo[1
;
2-b]pyridazine
;
Unicellular parasites
;
Leishmania
;
DYRK1A
;
CLK
s
刊名:European Journal of Medicinal Chemistry
出版年:2017
6.
Differential expression of circadian clock genes in two strains of beetles reveals candidates related to photoperiodic induction of summer diapause
作者:
Li Zhu
;
Wen Liu
;
liuwen@mail.hzau.edu.cn
;
Qian-Qian Tan
;
Chao-Liang Lei
;
Xiao-Ping Wang
关键词:
clk
;
clock
;
cry2
;
cryptochrome2
;
cyc
;
cycle
;
dbt
;
double-time
;
HD
;
high diapause
;
LD
;
long-day
;
NPD
;
non-photoperiodic-diapause
;
ORF
;
open reading frames
;
per
;
period
;
qRT-PCR
;
quantitative real-time PCR
;
sgg
;
shaggy
;
tim
;
timeless
;
vri
;
vrille
;
ZT
;
zeitgeber time
刊名:Gene
出版年:2017
7.
Nerve Growth Factor Promotes Gastric Tumorigenesis through Aberrant Cholinergic Signaling
作者:
Yoku Hayakawa
1
;
2
;
12
;
Kosuke Sakitani
1
;
12
;
Mitsuru Konishi
2
;
Samuel Asfaha
1
;
3
;
Ryota Niikura
2
;
Hiroyuki Tomita
4
;
Bernhard W. Renz
1
;
5
;
Yagnesh Tailor
1
;
Marina Macchini
1
;
Moritz Middelhoff
1
;
Zhengyu Jiang
1
;
Takayuki Tanaka
1
;
Zinaida A. Dubeykovskaya
1
;
Woosook Kim
1
;
Xiaowei Chen
1
;
Aleksandra M. Urbanska
1
;
Karan Nagar
1
;
Christoph B. Westphalen
1
;
6
;
Michael Quante
7
;
Chyuan-Sheng Lin
8
;
9
;
Michael D. Gershon
8
;
Akira Hara
4
;
Chun-Mei Zhao
10
;
Duan Chen
10
;
Daniel L. Worthley
1
;
11
;
Kazuhiko Koike
2
;
Timothy C. Wang
1
;
13
;
tcw21@columbia.edu
关键词:
NGF
;
gastric cancer
;
acetylcholine
;
Lgr5
;
wnt
;
YAP
;
D
clk
1
;
tuft cell
;
stem cell
;
muscarinic acetylcholine receptor type 3
刊名:Cancer Cell
出版年:2017
8.
Novel Ag/AgCl/K
6
Nb
10.8
O
30
photocatalyst and its enhanced visible light photocatalytic activities for the degradation of microcystin-LR and acid red G
作者:
Xi Zou
a
;
1
;
Zhen Wan
b
;
1
;
Chengyan Wan
a
;
chywan@mail.ihe.ac.cn" class="auth_mail" title="E-mail the corresponding author
;
zxi11@163.com" class="auth_mail" title="E-mail the corresponding author
;
Gaoke Zhang
b
;
Xiaojie Pan
a
;
Jianhua Peng
a
;
Jianbo Chang
a
关键词:
Heterostructures
;
Ag/AgCl/K6Nb10.8O30 composites
;
Microcystin-LR
;
Acid red G
;
Visible light irradiation
刊名:Journal of Molecular Catalysis A: Chemical
出版年:2016
9.
PDF Signaling Is an Integral Part of the Drosophila Circadian Molecular Oscillator
作者:
Shaul Mezan
1
;
Jean Daniel Feuz
2
;
Bart Deplancke
2
;
Sebastian Kadener
1
;
3
;
skadener@mail.huji.ac.il" class="auth_mail" title="E-mail the corresponding author
关键词:
CLK
;
PDF
;
circadian
;
Drosophila
;
transcriptional fluorescent reporters
;
brain culture
刊名:Cell Reports
出版年:2016
10.
Systematic diversification of benzylidene heterocycles yields novel inhibitor scaffolds selective for Dyrk1A,
Clk
1 and CK2
作者:
Marica Mariano
a
;
Rolf W. Hartmann
a
;
b
;
Matthias Engel
a
;
ma.engel@mx.uni-saarland.de" class="auth_mail" title="E-mail the corresponding author
关键词:
Dyrk1A
;
PI3 kinase
;
Alzheimer
;
Glioma
;
Multi-targeted inhibitor
刊名:European Journal of Medicinal Chemistry
出版年:2016
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