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在“Elsevier电子期刊”中，命中：258条，耗时：0.027986 秒

在所有数据库中总计命中：349条

1.Investigating Leber's hereditary optic neuropathy: Cell models and future perspectives

作者：Elona Jankauskaitė^a ; Ewa Bartnik^a ; ^b ; Agata Kodroń^a ; ^{agatakodron@wp.pl}

关键词：CRISPR ; Clustered Regularly Interspaced Short Palindromic Repeats ; EBV ; Epstein Barr virus ; LHON ; Leber's hereditary optic neuropathy ; RGC ; retinal ganglion cells ; EtBr ; ethidium bromide ; mitoTALENs ; mitochondria targeted transcription-activator-like effector nucleases

刊名：Mitochondrion

出版年：2017

2.An International Study of Emotional Response to Bilateral Vision Loss Using a Novel Graphical Online Assessment Tool

作者：Jesse Gale ; M.B. ; Ch.B. ; F.R.A.N.Z.C.O.^a ; ^b ; Matin Khoshnevis ; M.D.^a ; ^c ; Starleen E. Frousiakis ; M.D.^a ; ^d ; Rustum Karanjia ; M.D. ; Ph.D.^a ; ^e ; Lissa Poincenot ; M.B.A.^a ; Alfredo A. Sadun ; M.D. ; Ph.D.^a ; ^{alfredo.sadun@gmail.com} ; David A. Baron ; D.O. ; M.S.Ed.^f

关键词：leber hereditary optic neuropathy ; depression ; adaptation ; psychologic ; adjustment disorders ; blindness ; vision disorders ; Kupfer curve.

刊名：Psychosomatics

出版年：2017

3.Long-term outcomes of gene therapy for the treatment of Leber's hereditary optic neuropathy

作者：Shuo Yang^a ; ¹ ; Si-qi Ma^a ; ¹ ; Xing Wan^a ; ¹ ; Heng He^a ; ¹ ; Han Pei^a ; ¹ ; Min-jian Zhao^b ; Chen Chen^c ; Dao-wen Wang^c ; Xiao-yan Dong^d ; Jia-jia Yuan^a ; Bin Li^a ; ^e ; ^{libin-12@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：AAV ; adeno-associated virus ; BCVA ; best corrected visual acuity ; CF ; counting fingers ; ERG ; electroretinogram ; HM ; hand movement ; IOP ; intraocular pressure ; LHON ; Leber's hereditary optic neuropathy ; MD ; mean defect ; MtDNA ; mitochondrial DNA ; ND4 ; NADH&ndash ; ubiquinone oxidoreductase ; subunit 4 ; OCT ; optical coherence tomography ; rAAV2-ND4 ; recombinant adeno-associated virus carrying the ND4 gene ; RNFL ; retinal nerve fiber layer ; VEP ; visual evoked potential ; VFI ; visual field index

刊名：EBioMedicine

出版年：2016

4.Gene Therapy for Leber Hereditary Optic Neuropathy: Initial Results

作者：William J. Feuer ; MS ; Joyce C. Schiffman ; MS ; Janet L. Davis ; MD ; Vittorio Porciatti ; DSc ; Phillip Gonzalez ; CCRP ; Rajeshwari D. Koilkonda ; PhD ; Huijun Yuan ; PhD ; Anil Lalwani ; MS ; Byron L. Lam ; MD ; John Guy ; MD ; ^{JGuy@med.miami.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：AAV ; adeno-associated virus vector ; ACF ; anterior chamber fluid ; DMEM ; Dulbecco's modified Eagle's medium ; ETDRS ; Early Treatment Diabetic Retinopathy Study ; IOP ; intraocular pressure ; LHON ; Leber hereditary optic neuropathy ; mtDNA ; mitochondrial DNA ; NAb ; neutralizing antibody ; PCR ; polymerase chain reaction ; PERG ; pattern electroretinogram ; RNFL ; retinal nerve fiber layer ; scAAV ; self-complementary adeno-associated vector

刊名：Ophthalmology

出版年：2016

5.Emerging Mitochondrial Therapeutic Targets in Optic Neuropathies

作者：M.I.G. Lopez Sanchez^a ; ^b ; J.G. Crowston^a ; ^b ; D.A. Mackey^c ; I.A. Trounce^a ; ^b ; ^{i.trounce@unimelb.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：AAV ; adeno-associated virus ; ADOA ; autosomal dominant optic atrophy ; Cas 9 ; CRISPR-associated protein 9 ; CoQ10 ; coenzyme Q10 ; CR ; caloric restriction ; CRISPR ; clustered regularly interspaced short palindromic repeats ; E2 ; 17β-estradiol ; ER ; estrogen receptor ; FADH2 ; flavin adenine dinucleotide ; IOP ; intra-ocular pressure ; iPSC ; induced pluripotent stem cell ; LHON ; Leber hereditary optic neuropathy ; MELAS ; mitochondrial encephalomyopathy ; lactic acidosis ; and stroke-like episodes ; MERRF ; myocloni

刊名：Pharmacology and Therapeutics

出版年：2016

6.Beyond what the eye can see

作者：Kate E. Ahmad ; FRACP^a ; ^{kate.ahmad@health.nsw.gov.au" class="auth_mail" title="E-mail the corresponding author} ; Clare L. Fraser ; FRANZCO^b ; Carolyn M. Sue ; FRACP^c ; Jason J.S. Barton ; MD ; PhD ; FRCPC^d ; ^e ; ^f

关键词：optic neuropathy ; genetic visual loss ; mitochondrial disease ; Leber hereditary optic neuropathy ; deafness and diabetes

刊名：Survey of Ophthalmology

出版年：2016

7.Identification of small molecules that improve ATP synthesis defects conferred by Leber's hereditary optic neuropathy mutations

作者：Sandipan Datta ^{sddatta@ucdavis.edu" class="auth_mail" title="E-mail the corresponding author} ; Alexey Tomilov ^{atomilov@ucdavis.edu" class="auth_mail" title="E-mail the corresponding author} ; Gino Cortopassi ; ^{gcortopassi@ucdavis.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：LHON ; Mitochondria ; High-throughput screening ; Complex I

刊名：Mitochondrion

出版年：2016

8.A unique combination of rare mitochondrial ribosomal RNA variants affects the kinetics of complex I assembly

作者：Anna Maria Porcelli^a ; ^b ; Maria Antonietta Calvaruso^a ; Luisa Iommarini^a ; Ivana Kurelac^c ; Roberta Zuntini^c ; Simona Ferrari^c ; Giuseppe Gasparre^c ; ^{giuseppe.gasparre@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：mtDNA ; mitochondrial DNA ; rRNA ; ribosomal RNA ; CI ; respiratory complex I ; LHON ; Leber&rsquo ; s Hereditary Optic Neuropathy ; MELAS ; Myoclonic Epilepsy with Lactic Acidosis and Stroke-like episodes ; 2D BN/SDS-PAGE ; two dimensional Blue Native sodium-dodecyl sulphate polyacrylamide gel electrophoresis ; HmtDB ; Human Mitochondrial DataBase ; 1D BN-PAGE ; first dimension Blue Native sodium-dodecyl sulphate polyacrylamide gel electrophoresis ; ROS ; reactive oxygen species

刊名：International Journal of Biochemistry and Cell Biology

出版年：2016

9.Re: Feuer et al.: Gene therapy for Leber hereditary optic neuropathy: initial results (Ophthalmology 2016;123:558-70)

作者：Josef Finsterer ; MD ; PhD¹ ; ^{fipaps@yahoo.de" class="auth_mail" title="E-mail the corresponding author} ; Sinda Zarrouk-Mahjoub ; PhD²

刊名：Ophthalmology

出版年：2016

10.Leber hereditary optic neuropathy: What are the therapeutic perspectives?

刊名：Archivos de la Sociedad Española de Oftalmología (English Edition)

出版年：2016

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