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ACS电子期刊(12)
在“
ACS电子期刊
”中,
命中:
12
条,耗时:0.0469754 秒
在所有数据库中总计命中:
12
条
1.
Pyrido[4,3-e][1,2,4]triazolo[4,3-a]pyrazine
s
a
s
Selective, Brain Penetrant Pho
s
phodie
s
tera
s
e 2 (PDE2) Inhibitor
s
作者:
Frederik J. R. Rombout
s
;
Gary Tre
s
adern
;
Peter Buijn
s
ter
s
;
Xavier Langloi
s
;
Fulgencio Tovar
;
Thoma
s
B. Steinbrecher
;
Greet Vanhoof
;
Marijke
S
omer
s
;
Jo
s茅
-Ignacio
Andr茅s
;
Andr茅s
A.
Trabanco
刊名:AC
S
Medicinal Chemi
s
try Letter
s
出版年:2015
2.
1,4-Oxazine 尾-
S
ecreta
s
e 1 (BACE1) Inhibitor
s
: From Hit Generation to Orally Bioavailable Brain Penetrant Lead
s
作者:
Frederik J. R. Rombout
s
;
Gary Tre
s
adern
;
O
s
car Delgado
;
Carolina Mart铆nez-Lamenca
;
Michiel Van Gool
;
Ar谩nzazu Garc铆a-Molina
;
S
ergio A. Alon
s
o de Diego
;
Daniel Oehlrich
;
Hana Prokopcova
;
Jo
s茅
Manuel Alon
s
o
;
Nigel Au
s
tin
;
Herman Borghy
s
;
S
ven Van Brandt
;
Michel
S
urkyn
;
Michel De Cleyn
;
Ann Vo
s
;
Richard Alexander
;
Gregor Macdonald
;
Dieder Moechar
s
;
Harrie Gij
s
en
;
Andr茅s
A.
Trabanco
刊名:Journal of Medicinal Chemi
s
try
出版年:2015
3.
Benzazaborinine
s
a
s
Novel Bioi
s
o
s
teric Replacement
s
of Naphthalene: Propranolol a
s
an Example
作者:
Frederik J. R. Rombout
s
;
Fulgencio Tovar
;
Nigel Au
s
tin
;
Gary Tre
s
adern
;
Andr茅s
A.
Trabanco
刊名:Journal of Medicinal Chemi
s
try
出版年:2015
4.
S
tructure-Ba
s
ed De
s
ign of a Potent, Selective, and Brain Penetrating PDE2 Inhibitor with Demon
s
trated Target Engagement
作者:
Peter Buijn
s
ter
s
;
Meri De Angeli
s
;
Xavier Langloi
s
;
Frederik J. R. Rombout
s
;
Wendy
S
ander
s
on
;
Gary Tre
s
adern
;
Ali
s
on Ritchie
;
Andr茅s
A.
Trabanco
;
Greet VanHoof
;
Yve
s
Van Roo
s
broeck
;
Jo
s茅
-Ignacio
Andr茅s
刊名:AC
S
Medicinal Chemi
s
try Letter
s
出版年:2014
5.
Dia
s
tereo
s
elective Synthe
s
i
s
of 2-Phenyl-3-(trifluoromethyl)piperazine
s
a
s
Building Block
s
for Drug Di
s
covery
作者:
Mar铆a
S
谩nchez-Ro
s
ell贸
;
O
s
car Delgado
;
Natalia Mateu
;
Andr茅s
A.
Trabanco
;
Michiel Van Gool
;
S
anto
s
Fu
s
tero
刊名:Journal of Organic Chemi
s
try
出版年:2014
6.
Di
s
covery of 1-Butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-(1H)-pyridone (JNJ-40411813): A Novel Po
s
itive Allo
s
teric Modulator of the Metabotropic Glutamate 2 Receptor
作者:
Jo
s茅
Mar铆a Cid
;
Gary Tre
s
adern
;
Guillaume Duvey
;
Robert L眉tjen
s
;
Terry Finn
;
Jean-Philippe Rocher
;
S
onia Poli
;
Juan Antonio Vega
;
Ana I
s
abel de Luca
s
;
Encarnaci贸n Mate
s
anz
;
Mar铆a Lourde
s
Linare
s
;
Jo
s茅
Ignacio
Andr茅s
;
Je
s
煤
s
Alcazar
;
Jo
s茅
Manuel Alon
s
o
;
Gregor J. Macdonald
;
Daniel Oehlrich
;
Hilde Lavrey
s
en
;
Abdelah Ahnaou
;
Wilhelmu
s
Drinkenburg
;
Claire Mackie
;
S
tefan Pype
;
David Gallacher
;
Andr茅s
A.
Trabanco
刊名:Journal of Medicinal Chemi
s
try
出版年:2014
7.
Dihydrothiazolopyridone Derivative
s
a
s
a Novel Family of Po
s
itive Allo
s
teric Modulator
s
of the Metabotropic Glutamate 5 (mGlu5) Receptor
作者:
Jo
s茅
Manuel Bartolom
茅
-Nebreda
;
S
u
s
ana Conde-Ceide
;
Franci
s
ca Delgado
;
Laura Iturrino
;
Joaqu铆n Pa
s
tor
;
Miguel 脕ngel Pena
;
Andr茅s
A.
Trabanco
;
Gary Tre
s
adern
;
Carola M. Wa
ss
vik
;
S
haun R. Stauffer
;
S
atyawan Jadhav
;
Kiran Gogi
;
Paige N. Vin
s
on
;
Meredith J. Noetzel
;
Emily Day
s
;
C. David Weaver
;
Craig W. Lind
s
ley
;
Colleen M. Ni
s
wender
;
Carrie K. Jone
s
;
P. Jeffrey Conn
;
Frederik Rombout
s
;
Hilde Lavrey
s
en
;
Gregor J. Macdonald
;
Claire Mackie
;
Thoma
s
Steckler
刊名:Journal of Medicinal Chemi
s
try
出版年:2013
8.
S
ynthe
s
i
s
, Evaluation, and Radiolabeling of New Potent Po
s
itive Allo
s
teric Modulator
s
of the Metabotropic Glutamate Receptor 2 a
s
Potential Tracer
s
for Po
s
itron Emi
ss
ion Tomography Imaging
作者:
Jo
s茅
-Ignacio
Andr茅s
;
Je
s
煤
s
Alc谩zar
;
Jo
s茅
Mar铆a Cid
;
Meri De Angeli
s
;
Laura Iturrino
;
Xavier Langloi
s
;
Hilde Lavrey
s
en
;
Andr茅s
A.
Trabanco
;
S
ofie Celen
;
Guy Borman
s
刊名:Journal of Medicinal Chemi
s
try
出版年:2012
9.
Di
s
covery of 3-Cyclopropylmethyl-7-(4-phenylpiperidin-1-yl)-8-trifluoromethyl[1,2,4]triazolo[4,3-a]pyridine (JNJ-42153605): A Po
s
itive Allo
s
teric Modulator of the Metabotropic Glutamate 2 Recep
作者:
Jo
s
e Mar铆a Cid
;
Gary Tre
s
adern
;
Juan Antonio Vega
;
Ana I
s
abel de Luca
s
;
Encarnaci贸n Mate
s
anz
;
Laura Iturrino
;
Mar铆a Lourde
s
Linare
s
;
Ar谩nzazu Garcia
;
Jo
s茅
Ignacio
Andr茅s
;
Gregor J. Macdonald
;
Daniel Oehlrich
;
Hilde Lavrey
s
en
;
Anton Megen
s
;
Abdellah Ahnaou
;
Wilhelmu
s
Drinkenburg
;
Claire Mackie
;
S
tefan Pype
;
David Gallacher
;
Andr茅s
A.
Trabanco
刊名:Journal of Medicinal Chemi
s
try
出版年:2012
10.
Imidazo[1,2-a]pyridine
s
: Orally Active Po
s
itive Allo
s
teric Modulator
s
of the Metabotropic Glutamate 2 Receptor
作者:
Andr茅s
A.
Trabanco
;
Gary Tre
s
adern
;
Gregor J. Macdonald
;
Juan Antonio Vega
;
Ana I
s
abel de Luca
s
;
Encarnaci贸n Mate
s
anz
;
Ar谩nzazu Garc铆a
;
Mar铆a Lourde
s
Linare
s
;
S
ergio A. Alon
s
o de Diego
;
Jo
s茅
Manuel Alon
s
o
;
Daniel Oehlrich
;
Abdelah Ahnaou
;
Wilhelmu
s
Drinkenburg
;
Claire Mackie
;
Jo
s茅
Ignacio
Andr茅s
;
Hilde Lavrey
s
en
;
Jo
s茅
Mar铆a Cid
刊名:Journal of Medicinal Chemi
s
try
出版年:2012
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