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Elsevier电子期刊(5)
ACS电子期刊(8)
在“
ACS电子期刊
”中,
命中:
8
条,耗时:小于0.01 秒
在所有数据库中总计命中:
13
条
1.
Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality
作者:
Christopher R. ButlerKevin Ogilvie
;
Luis Martinez-Alsina
;
Gabriela Barreiro
;
Elizabeth M. Beck
;
Charles E. Nolan
;
Kevin Atchison
;
Eric Benvenuti
;
Leanne Buzon
;
Shawn Doran
;
Cathleen Gonzales
;
Christopher J. Helal
;
Xinjun Hou
;
Mei-Hui Hsu
;
Eric F. Johnson
;
Kimberly Lapham
;
Lorraine Lanyon
;
Kevin Parris
;
Brian T. O’Neill
;
David Riddell
;
Ashley Robshaw
;
Felix
Vajdos
;
Michael A. Brodney
刊名:Journal of Medicinal Chemistry
出版年:2017
2.
Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition
作者:
Jean-Baptiste Telliez
;
Martin E. Dowty
;
Lu Wang
;
Jason Jussif
;
Tsung Lin
;
Li Li
;
Erick Moy
;
Paul Balbo
;
Wei Li
;
Yajuan Zhao
;
Kimberly Crouse
;
Caitlyn Dickinson
;
Peter Symanowicz
;
Martin Hegen
;
Mary Ellen Banker
;
Fabien Vincent
;
Ray Unwalla
;
Sidney Liang
;
Adam M. Gilbert
;
Matthew F. Brown
;
Matthew Hayward
;
Justin Montgomery
;
Xin Yang
;
Jonathan Bauman
;
John I. Trujillo
;
Agustin Casimiro-Garcia
;
Felix
F.
Vajdos
;
Louis Leung
;
Kieran F. Geoghegan
;
Amira Quazi
;
Dejun Xuan
;
Lyn Jones
;
Erik Hett
;
Katherine Wright
;
James D. Clark
;
Atli Thorarensen
刊名:ACS Chemical Biology
出版年:2016
3.
Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design
作者:
Christopher R. Butler
;
Michael A. Brodney
;
Elizabeth M. Beck
;
Gabriela Barreiro
;
Charles E. Nolan
;
Feng Pan
;
Felix
Vajdos
;
Kevin Parris
;
Alison H. Varghese
;
Christopher J. Helal
;
Ricardo Lira
;
Shawn D. Doran
;
David R. Riddell
;
Leanne M. Buzon
;
Jason K. Dutra
;
Luis A. Martinez-Alsina
;
Kevin Ogilvie
;
John C. Murray
;
Joseph M. Young
;
Kevin Atchison
;
Ashley Robshaw
;
Cathleen Gonzales
;
Jinlong Wang
;
Yong Zhang
;
Brian T. O鈥橬eill
刊名:Journal of Medicinal Chemistry
出版年:2015
4.
Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes
作者:
David A. Griffith
;
Daniel W. Kung
;
William P. Esler
;
Paul A. Amor
;
Scott W. Bagley
;
Carine Beysen
;
Santos Carvajal-Gonzalez
;
Shawn D. Doran
;
Chris Limberakis
;
Alan M. Mathiowetz
;
Kirk McPherson
;
David A. Price
;
Eric Ravussin
;
Gabriele E. Sonnenberg
;
James A. Southers
;
Laurel J. Sweet
;
Scott M. Turner
;
Felix
F.
Vajdos
刊名:Journal of Medicinal Chemistry
出版年:2014
5.
Deconstruction of Activity-Dependent Covalent Modification of Heme in Human Neutrophil Myeloperoxidase by Multistage Mass Spectrometry (MS4)
作者:
Kieran F. Geoghegan
;
Alison H. Varghese
;
Xidong Feng
;
Andrew J. Bessire
;
James J. Conboy
;
Roger B. Ruggeri
;
Kay Ahn
;
Samantha N. Spath
;
Sergey V. Filippov
;
Steven J. Conrad
;
Philip A. Carpino
;
Cristiano R. W. Guimar茫es
;
Felix
F.
Vajdos
刊名:Biochemistry
出版年:2012
6.
Spirocyclic Sulfamides as 尾-Secretase 1 (BACE-1) Inhibitors for the Treatment of Alzheimer鈥檚 Disease: Utilization of Structure Based Drug Design, WaterMap, and CNS Penetration Studies To Identify Cent
作者:
Michael A. Brodney
;
Gabriela Barreiro
;
Kevin Ogilvie
;
Eva Hajos-Korcsok
;
John Murray
;
Felix
Vajdos
;
Claude Ambroise
;
Curt Christoffersen
;
Katherine Fisher
;
Lorraine Lanyon
;
JianHua Liu
;
Charles E. Nolan
;
Jane M. Withka
;
Kris A. Borzilleri
;
Ivan Efremov
;
Christine E. Oborski
;
Alison Varghese
;
Brian T. O鈥橬eill
刊名:Journal of Medicinal Chemistry
出版年:2012
7.
Discovery and Optimization of a Novel Spiropyrrolidine Inhibitor of 尾-Secretase (BACE1) through Fragment-Based Drug Design
作者:
Ivan V. Efremov
;
Felix
F.
Vajdos
;
Kris A. Borzilleri
;
Steven Capetta
;
Hou Chen
;
Peter H. Dorff
;
Jason K. Dutra
;
Steven W. Goldstein
;
Mahmoud Mansour
;
Alexander McColl
;
Stephen Noell
;
Christine E. Oborski
;
Thomas N. O鈥機onnell
;
Theresa J. O鈥橲ullivan
;
Jayvardhan Pandit
;
Hong Wang
;
BinQing Wei
;
Jane M. Withka
刊名:Journal of Medicinal Chemistry
出版年:2012
8.
Crystal Structure of Human Insulin-like Growth Factor-1: Detergent Binding Inhibits Binding Protein Interactions
作者:
Felix
F.
Vajdos
;
Mark Ultsch
;
Michelle L. Schaffer
;
Kurt D. Deshayes
;
Jun Liu
;
Nicholas J. Skelton
;
and Abraham M. de Vos
刊名:Biochemistry
出版年:2001
1
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