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ACS电子期刊(7)
在“
ACS电子期刊
”中,
命中:
7
条,耗时:0.0399812 秒
在所有数据库中总计命中:
40
条
1.
The Rational De
s
ign of Selective Benzoxazepin Inhibitor
s
of the α-I
s
oform of Pho
s
phoino
s
itide 3-Kina
s
e Culminating in the Identification of (S)-2-((2-(1-I
s
opropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydroben
作者:
Timothy P. Heffron
;
Robert A. Heald
;
Chudi Ndubaku
;
BinQing Wei
;
Martin Augi
s
tin
;
S
teven Do
;
Kyle Edgar
;
Charle
s
Eigenbrot
;
Lori
Friedman
;
Emanuela Gancia
;
Philip
S
. Jack
s
on
;
Graham Jone
s
;
Alek
s
ander Kole
s
nikov
;
Le
s
lie B. Lee
;
John D. Le
s
nick
;
Cri
s
tina Lewi
s
;
Neville McLean
;
Mario M?rtl
;
Jim Nonomiya
;
Jodie Pang
;
S
teve Price
;
Wei Wei Prior
;
Laurent
S
alphati
;
S
teve Sideri
s
;
S
teven T. Staben
;
S
tefan Steinbacher
;
Vickie T
s
ui
;
Jeffrey Wallin
;
Deepak
S
ampath
;
Alan G. Olivero
刊名:Journal of Medicinal Chemi
s
try
出版年:2016
2.
Back Pocket Flexibility Provide
s
Group II p21-Activated Kina
s
e (PAK) Selectivity for Type I 1/2 Kina
s
e Inhibitor
s
作者:
S
teven T. Staben
;
Jianwen A. Feng
;
Karen Lyle
;
Marcia Belvin
;
Ja
s
on Bogg
s
;
Ja
s
on D. Burch
;
Ching-ching Chua
;
Haifeng Cui
;
Antonio G. DiPa
s
quale
;
Lori
S
.
Friedman
;
Chri
s
topher Hei
s
e
;
Hartmut Koeppen
;
Adrian Kotey
;
Robert Mintzer
;
Angela Oh
;
David Allen Robert
s
;
Lionel Rouge
;
Joachim Rudolph
;
Chri
s
tine Tam
;
Weiru Wang
;
Yi
s
ong Xiao
;
Amy Young
;
Yamin Zhang
;
Klau
s
P. Hoeflich
刊名:Journal of Medicinal Chemi
s
try
出版年:2014
3.
Di
s
covery and Biological Profiling of Potent and Selective mTOR Inhibitor GDC-0349
作者:
Zhonghua Pei
;
Elizabeth Blackwood
;
Lichuan Liu
;
S
hiva Malek
;
Marcia Belvin
;
Michael F. T. Koehler
;
Daniel F. Ortwine
;
Huifen Chen
;
Frederick Cohen
;
Jane R. Kenny
;
Philippe Bergeron
;
Kevin Lau
;
Cuong Ly
;
Xianrui Zhao
;
Anthony A. E
s
trada
;
Tom Truong
;
Jennifer A. Epler
;
Jim Nonomiya
;
Lan Trinh
;
S
teve Sideri
s
;
John Le
s
nick
;
Linda Bao
;
Ulka Vijapurkar
;
S
ophie Mukadam
;
S
uzanne Tay
;
Gauri De
s
hmukh
;
Yung-H
s
iang Chen
;
Xiao Ding
;
Lori
S
.
Friedman
;
Jo
s
eph P. Ly
ss
ikato
s
刊名:AC
S
Medicinal Chemi
s
try Letter
s
出版年:2013
4.
Pyrimidoaminotropane
s
a
s
Potent, Selective, and Efficaciou
s
Small Molecule Kina
s
e Inhibitor
s
of the Mammalian Target of Rapamycin (mTOR)
作者:
Anthony A. E
s
trada
;
Daniel G.
S
hore
;
Elizabeth Blackwood
;
Yung-H
s
iang Chen
;
Gauri De
s
hmukh
;
Xiao Ding
;
Antonio G. DiPa
s
quale
;
Jennifer A. Epler
;
Lori
S
.
Friedman
;
Michael F. T. Koehler
;
Lichuan Liu
;
S
hiva Malek
;
Jim Nonomiya
;
Daniel F. Ortwine
;
Zhonghua Pei
;
S
teve Sideri
s
;
Frederic
S
t-Jean
;
Lan Trinh
;
Tom Truong
;
Jo
s
eph P. Ly
ss
ikato
s
刊名:Journal of Medicinal Chemi
s
try
出版年:2013
5.
Di
s
covery of 2-{3-[2-(1-I
s
opropyl-3-methyl-1H-1,2鈥?-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl]-1H-pyrazol-1-yl}-2-methylpropanamide (GDC-0032): A 尾-Sparing
作者:
Chudi O. Ndubaku
;
Timothy P. Heffron
;
S
teven T. Staben
;
Matthew Baumgardner
;
Nicole Blaquiere
;
Erin Bradley
;
Richard Bull
;
S
teven Do
;
Jennafer Dot
s
on
;
Danette Dudley
;
Kyle A. Edgar
;
Lori
S
.
Friedman
;
Richard Gold
s
mith
;
Robert A. Heald
;
Alek
s
andr Kole
s
nikov
;
Le
s
lie Lee
;
Cri
s
tina Lewi
s
;
Michelle Nannini
;
Jim Nonomiya
;
Jodie Pang
;
S
teve Price
;
Wei Wei Prior
;
Laurent
S
alphati
;
S
teve Sideri
s
;
Jeffery J. Wallin
;
Lan Wang
;
BinQing Wei
;
Deepak
S
ampath
;
Alan G. Olivero
刊名:Journal of Medicinal Chemi
s
try
出版年:2013
6.
Di
s
covery of a Potent, Selective, and Orally Available Cla
ss
I Pho
s
phatidylino
s
itol 3-Kina
s
e (PI3K)/Mammalian Target of Rapamycin (mTOR) Kina
s
e Inhibitor (GDC-0980) for the Treatment of Cancer
作者:
Daniel P.
S
utherlin
;
Linda Bao
;
Megan Berry
;
Georgette Ca
s
tanedo
;
Irina Chuckowree
;
Jenna Dot
s
on
;
Adrian Folk
s
;
Lori
Friedman
;
Richard Gold
s
mith
;
Janet Gunzner
;
Timothy Heffron
;
John Le
s
nick
;
Cri
s
tina Lewi
s
;
S
imon Mathieu
;
Jeremy Murray
;
Jim Nonomiya
;
Jodie Pang
;
Niel Pegg
;
Wei Wei Prior
;
Lionel Rouge
;
Laurent
S
alphati
;
Deepak
S
ampath
;
Qingping Tian
;
Vickie T
s
ui
;
Nan Chi Wan
;
S
humei Wang
;
BinQing Wei
;
Chri
s
tian Wie
s
mann
;
Ping Wu
;
Bing-Yan Zhu
;
Alan Olivero
刊名:Journal of Medicinal Chemi
s
try
出版年:2011
7.
The Identification of 2-(1H-Indazol-4-yl)-6-(4-methane
s
ulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) a
s
a Potent, Selective, Orally Bioavailable Inhib
作者:
Adrian J. Folke
s
;
Khatereh Ahmadi
;
Wendy K. Alderton
;
S
onia Alix
;
S
tewart J. Baker
;
Gary Box
;
Irina
S
. Chuckowree
;
Paul A. Clarke
;
Paul Depledge
;
S
uzanne A. Eccle
s
;
Lori
S
.
Friedman
;
Angela Haye
s
;
Tim
刊名:Journal of Medicinal Chemi
s
try
出版年:2008
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