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Elsevier电子期刊(10)
ACS电子期刊(19)
在“
ACS电子期刊
”中,
命中:
19
条,耗时:小于0.01 秒
在所有数据库中总计命中:
29
条
1.
Discovery of Phosphodiesterase 10A (PDE10A) PET Tracer AMG 580 to Support Clinical Studies
作者:
Essa Hu
;
Ning Chen
;
Roxanne K. Kunz
;
Dah-Ren Hwang
;
Klaus Michelsen
;
Carl Davis
;
Ji Ma
;
Jianxia Shi
;
Dianna Lester-Zeiner
;
Randall
Hungate
;
James Treanor
;
Hang Chen
;
Jennifer R. Allen
刊名:ACS Medicinal Chemistry Letters
出版年:2016
2.
Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase–Glucokinase Regulatory Protein (GK–GKRP) Binding: Strategic Use of a N → S (nN → σ*S–X) Interaction fo
作者:
Lewis D. Pennington
;
Michael D. Bartberger
;
Michael D. Croghan
;
Kristin L. Andrews
;
Kate S. Ashton
;
Matthew P. Bourbeau
;
Jie Chen
;
Samer Chmait
;
Rod Cupples
;
Christopher Fotsch
;
Joan Helmering
;
Fang-Tsao Hong
;
Randall
W.
Hungate
;
Steven R. Jordan
;
Ke Kong
;
Longbin Liu
;
Klaus Michelsen
;
Carolyn Moyer
;
Nobuko Nishimura
;
Mark H. Norman
;
Andreas Reichelt
;
Aaron C. Siegmund
;
Glenn Sivits
;
Seifu Tadesse
;
Christopher M. Tegley
;
Gwyneth Van
;
Kevin C. Yang
;
Guomin Yao
;
Jiandong Zhang
;
David J. Lloyd
;
Clarence Hale
;
David J. St. Jean Jr.
刊名:Journal of Medicinal Chemistry
出版年:2015
3.
Discovery and in Vivo Evaluation of (S)-N-(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and Related PI3K未 Inhibitors for Inflammation and Autoimmune
作者:
Timothy D. Cushing
;
Xiaolin Hao
;
Youngsook Shin
;
Kristin Andrews
;
Matthew Brown
;
Mario Cardozo
;
Yi Chen
;
Jason Duquette
;
Ben Fisher
;
Felix Gonzalez-Lopez de Turiso
;
Xiao He
;
Kirk R. Henne
;
Yi-Ling Hu
;
Randall
Hungate
;
Michael G. Johnson
;
Ron C. Kelly
;
Brian Lucas
;
John D. McCarter
;
Lawrence R. McGee
;
Julio C. Medina
;
Tisha San Miguel
;
Deanna Mohn
;
Vatee Pattaropong
;
Liping H. Pettus
;
Andreas Reichelt
;
Robert M. Rzasa
;
Jennifer Seganish
;
Andrew S. Tasker
;
Robert C. Wahl
;
Sharon Wannberg
;
Douglas A. Whittington
;
John Whoriskey
;
Gang Yu
;
Leeanne Zalameda
;
Dawei Zhang
;
Daniela P. Metz
刊名:Journal of Medicinal Chemistry
出版年:2015
4.
Discovery of Clinical Candidate 1-(4-(3-(4-(1H-Benzo[d]imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)ethanone (AMG 579), A Potent, Selective, and Efficacious Inhibitor of Phos
作者:
Essa Hu
;
Ning Chen
;
Matthew P. Bourbeau
;
Paul E. Harrington
;
Kaustav Biswas
;
Roxanne K. Kunz
;
Kristin L. Andrews
;
Samer Chmait
;
Xiaoning Zhao
;
Carl Davis
;
Ji Ma
;
Jianxia Shi
;
Dianna Lester-Zeiner
;
Jean Danao
;
Jessica Able
;
Madelyn Cueva
;
Santosh Talreja
;
Thomas Kornecook
;
Hang Chen
;
Amy Porter
;
Randall
Hungate
;
James Treanor
;
Jennifer R. Allen
刊名:Journal of Medicinal Chemistry
出版年:2014
5.
Dipeptidyl-Quinolone Derivatives Inhibit Hypoxia Inducible Factor-1α Prolyl Hydroxylases-1, -2, and -3 with Altered Selectivity
作者:
Justin K. Murray
;
Chenera Balan
;
Alan M. Allgeier
;
Annie Kasparian
;
Vellarkad Viswanadhan
;
Christopher Wilde
;
Jennifer R. Allen
;
Sean C. Yoder
;
Gloria Biddlecome
;
Randall
W.
Hungate
;
Les P. Miranda
刊名:Journal of Combinatorial Chemistry
出版年:2010
6.
Discovery of a Potent, Orally Active 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor for Clinical Study: Identification of (S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-y
作者:
Murielle M. Vniant
;
Clarence Hale
;
Randall
W.
Hungate
;
Kyung Gahm
;
Maurice G. Emery
;
Janan Jona
;
Smriti Joseph
;
Jeffrey Adams
;
Andrew Hague
;
George Moniz
;
Jiandong Zhang
;
Michael D. Bartberger
;
Vivian
刊名:Journal of Medicinal Chemistry
出版年:2010
7.
Stereoselective Synthesis of anti-N-Protected 3-Amino-1,2-epoxides by Nucleophilic Addition to N-tert-Butanesulfinyl Imine of a Glyceraldehyde Synthon
作者:
Scott S. Harried
;
Michael D. Croghan
;
Matthew R. Kaller
;
Patricia Lopez
;
Wenge Zhong
;
Randall
Hungate
;
Paul J. Reider
刊名:Journal of Organic Chemistry
出版年:2009
8.
Discovery and Optimization of Chromenotriazolopyrimidines as Potent Inhibitors of the Mouse Double Minute 2−Tumor Protein 53 Protein−Protein Interaction
作者:
John G. Allen
;
Matthew P. Bourbeau
;
G. Erich Wohlhieter
;
Michael D. Bartberger
;
Klaus Michelsen
;
Randall
Hungate
;
Robert C. Gadwood
;
Rick D. Gaston
;
Bruce Evans
;
Larry W. Mann
;
Michael E. Matison
;
Ste
刊名:Journal of Medicinal Chemistry
出版年:2009
9.
Further Studies with the 2-Amino-1,3-thiazol-4(5H)-one Class of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors: Reducing Pregnane X Receptor Activity and Exploring Activity in a Monkey
作者:
Christopher Fotsch
;
Michael D. Bartberger
;
Eric A. Bercot
;
Michelle Chen
;
Rod Cupples
;
Maury Emery
;
Jenne Fretland
;
Anil Guram
;
Clarence Hale
;
Nianhe Han
;
Dean Hickman
;
Randall
W.
Hungate
;
Michael Hay
刊名:Journal of Medicinal Chemistry
出版年:2008
10.
Discovery of Novel, Potent Benzamide Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Exhibiting Oral Activity in an Enzyme Inhibition ex Vivo Model
作者:
Lisa D. Julian
;
Zhulun Wang
;
Tracy Bostick
;
Seb Caille
;
Rebekah Choi
;
Michael DeGraffenreid
;
Yongmei Di
;
Xiao He
;
Randall
W.
Hungate
;
Juan C. Jaen
;
Jinsong Liu
;
Mario Monshouwer
;
Dustin McMinn
;
Yosup
刊名:Journal of Medicinal Chemistry
出版年:2008
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