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在“
ACS电子期刊
”中,
命中:
122
条,耗时:小于0.01 秒
在所有数据库中总计命中:
1,260
条
1.
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives
作者:
Susan M. Westaway
;
Alex G. S. Preston
;
Michael D. Barker
;
Fiona Brown
;
Jack A. Brown
;
Matthew
Campbell
;
Chun-wa Chung
;
Hawa Diallo
;
Clement Douault
;
Gerard Drewes
;
Robert
Eagle
;
Laurie Gordon
;
Carl Haslam
;
Thomas G. Hayhow
;
Philip G. Humphreys
;
Gerard Joberty
;
Roy Katso
;
Laurens Kruidenier
;
Melanie Leveridge
;
John Liddle
;
Julie Mosley
;
Marcel Muelbaier
;
Rebecca Randle
;
Inma Rioja
;
Anne Rueger
;
Gail A. Seal
;
Robert
J. Sheppard
;
Onkar Singh
;
Joanna Taylor
;
Pamela Thomas
;
Douglas Thomson
;
David M. Wilson
;
Kevin Lee
;
Rab K. Prinjha
刊名:Journal of Medicinal Chemistry
出版年:2016
2.
Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials
作者:
Brian K. Albrecht
;
Victor S. Gehling
;
Michael C. Hewitt
;
Rishi G. Vaswani
;
Alexandre Côté
;
Yves Leblanc
;
Christopher G. Nasveschuk
;
Steve Bellon
;
Louise Bergeron
;
Robert
Campbell
;
Nico Cantone
;
Michael R. Cooper
;
Richard T. Cummings
;
Hariharan Jayaram
;
Shivangi Joshi
;
Jennifer A. Mertz
;
Adrianne Neiss
;
Emmanuel Normant
;
Michael O’Meara
;
Eneida Pardo
;
Florence Poy
;
Peter Sandy
;
Jeffrey Supko
;
Robert
J. Sims III
;
Jean-Christophe Harmange
;
Alexander M. Taylor
;
James E. Audia
刊名:Journal of Medicinal Chemistry
出版年:2016
3.
Discovery of Tetrahydropyrazolopyridine as Sphingosine 1-Phosphate Receptor 3 (S1P3)-Sparing S1P1 Agonists Active at Low Oral Doses
作者:
Emmanuel H. Demont
;
James M. Bailey
;
Rino A. Bit
;
Jack A. Brown
;
Colin A.
Campbell
;
Nigel Deeks
;
Simon J. Dowell
;
Colin Eldred
;
Pam Gaskin
;
James R. J. Gray
;
Andrea Haynes
;
David J. Hirst
;
Duncan S. Holmes
;
Umesh Kumar
;
Mary A. Morse
;
Greg J. Osborne
;
Jessica F. Renaux
;
Gail A. L. Seal
;
Chris A. Smethurst
;
Simon Taylor
;
Robert
Watson
;
Robert
Willis
;
Jason Witherington
刊名:Journal of Medicinal Chemistry
出版年:2016
4.
Optimization, Production, and Characterization of a CpG-Oligonucleotide-Ficoll Conjugate Nanoparticle Adjuvant for Enhanced Immunogenicity of Anthrax Protective Antigen
作者:
Bob Milley
;
Radwan Kiwan
;
Gary S. Ott
;
Carlo Calacsan
;
Melissa Kachura
;
John D.
Campbell
;
Holger Kanzler
;
Robert
L. Coffman
刊名:Bioconjugate Chemistry
出版年:2016
5.
Rational Design of Calpain Inhibitors Based on Calpastatin Peptidomimetics
作者:
Kristin E. Low
;
Spencer Ler
;
Kevin J. Chen
;
Robert
L.
Campbell
;
Jennifer L. Hickey
;
Joanne Tan
;
Conor C. G. Scully
;
Peter L. Davies
;
Andrei K. Yudin
;
Serge Zaretsky
刊名:Journal of Medicinal Chemistry
出版年:2016
6.
The Importance of Being Me: Magic Methyls, Methyltransferase Inhibitors, and the Discovery of Tazemetostat
作者:
Kevin W. Kuntz
;
John E.
Campbell
;
Heike Keilhack
;
Roy M. Pollock
;
Sarah K. Knutson
;
Margaret Porter-Scott
;
Victoria M. Richon
;
Chris J. Sneeringer
;
Tim J. Wigle
;
Christina J. Allain
;
Christina R. Majer
;
Mikel P. Moyer
;
Robert
A. Copeland
;
Richard Chesworth
刊名:Journal of Medicinal Chemistry
出版年:2016
7.
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives
作者:
Susan M. Westaway
;
Alex G. S. Preston
;
Michael D. Barker
;
Fiona Brown
;
Jack A. Brown
;
Matthew
Campbell
;
Chun-wa Chung
;
Gerard Drewes
;
Robert
Eagle
;
Neil Garton
;
Laurie Gordon
;
Carl Haslam
;
Thomas G. Hayhow
;
Philip G. Humphreys
;
Gerard Joberty
;
Roy Katso
;
Laurens Kruidenier
;
Melanie Leveridge
;
Michelle Pemberton
;
Inma Rioja
;
Gail A. Seal
;
Tracy Shipley
;
Onkar Singh
;
Colin J. Suckling
;
Joanna Taylor
;
Pamela Thomas
;
David M. Wilson
;
Kevin Lee
;
Rab K. Prinjha
刊名:Journal of Medicinal Chemistry
出版年:2016
8.
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy
作者:
Beatriz Baragaña
;
Neil R. Norcross
;
Caroline Wilson
;
Achim Porzelle
;
Irene Hallyburton
;
Raffaella Grimaldi
;
Maria Osuna-Cabello
;
Suzanne Norval
;
Jennifer Riley
;
Laste Stojanovski
;
Frederick R. C. Simeons
;
Paul G. Wyatt
;
Michael J. Delves
;
Stephan Meister
;
Sandra Duffy
;
Vicky M. Avery
;
Elizabeth A. Winzeler
;
Robert
E. Sinden
;
Sergio Wittlin
;
Julie A. Frearson
;
David W. Gray
;
Alan H. Fairlamb
;
David Waterson
;
Simon F.
Campbell
;
Paul Willis
;
Kevin D. Read
;
Ian H. Gilbert
刊名:Journal of Medicinal Chemistry
出版年:2016
9.
Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients
作者:
Shizhen Qin
;
Yong Zhou
;
Li Gray
;
Ulrike Kusebauch
;
Laurence McEvoy
;
Daniel J. Antoine
;
Lucy Hampson
;
Kevin B. Park
;
David
Campbell
;
Juan Caballero
;
Gustavo Glusman
;
Xiaowei Yan
;
Taek-Kyun Kim
;
Yue Yuan
;
Kai Wang
;
Lee Rowen
;
Robert
L. Moritz
;
Gilbert S. Omenn
;
Munir Pirmohamed
;
Leroy Hood
刊名:Journal of Proteome Research
出版年:2016
10.
Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymp
作者:
Rishi G. Vaswani
;
Victor S. Gehling
;
Les A. Dakin
;
Andrew S. Cook
;
Christopher G. Nasveschuk
;
Martin Duplessis
;
Priyadarshini Iyer
;
Srividya Balasubramanian
;
Feng Zhao
;
Andrew C. Good
;
Robert
Campbell
;
Christina Lee
;
Nico Cantone
;
Richard T. Cummings
;
Emmanuel Normant
;
Steven F. Bellon
;
Brian K. Albrecht
;
Jean-Christophe Harmange
;
Patrick Trojer
;
James E. Audia
;
Ying Zhang
;
Neil Justin
;
Shuyang Chen
;
Jon R. Wilson
;
Steven J. Gamblin
刊名:Journal of Medicinal Chemistry
出版年:2016
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