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CNKI学位论文(31)
知网期刊论文(1)
在“
ACS电子期刊
”中,
命中:
8
条,耗时:小于0.01 秒
在所有数据库中总计命中:
32
条
1.
Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates
作者:
Mihirbaran Mandal
;
Yusheng Wu
;
Jeffrey Misiaszek
;
Guoqing Li
;
Alexei Buevich
;
John P. Caldwell
;
Xiaoxiang Liu
;
Robert D. Mazzola
;
Peter Orth
;
Corey Strickland
;
Johannes Voigt
;
Hongwu Wang
;
Zhaoning Zhu
;
Xia Chen
;
Michael Grzelak
;
Lynn A. Hyde
;
Reshma Kuvelkar
;
Prescott T. Leach
;
Giuseppe Terracina
;
Lili Zhang
;
Qi Zhang
;
Maria S. Michener
;
Brad Smith
;
Kathleen Cox
;
Diane Grotz
;
Leonard Favreau
;
Kaushik Mitra
;
Irina Kazakevich
;
Brian
A.
McKittrick
;
William Greenlee
;
Matthew E. Kennedy
;
Eric M. Parker
;
Jared N. Cumming
;
Andrew W. Stamford
刊名:Journal of Medicinal Chemistry
出版年:2016
2.
Biased Ligand Modulation of Seven Transmembrane Receptors (7TMRs): Functional Implications for Drug Discovery
作者:
Craig C. Correll
;
Brian
A.
McKittrick
刊名:Journal of Medicinal Chemistry
出版年:2014
3.
Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor That Affords Robust CNS A尾 Reduction
作者:
Andrew W. Stamford
;
Jack D. Scott
;
Sarah W. Li
;
Suresh Babu
;
Dawit Tadesse
;
Rachael Hunter
;
Yusheng Wu
;
Jeffrey Misiaszek
;
Jared N. Cumming
;
Eric J. Gilbert
;
Chunli Huang
;
Brian
A.
McKittrick
;
Liwu Hong
;
Tao Guo
;
Zhaoning Zhu
;
Corey Strickland
;
Peter Orth
;
Johannes H. Voigt
;
Matthew E. Kennedy
;
Xia Chen
;
Reshma Kuvelkar
;
Robert Hodgson
;
Lynn A. Hyde
;
Kathleen Cox
;
Leonard Favreau
;
Eric M. Parker
;
William J. Greenlee
刊名:ACS Medicinal Chemistry Letters
出版年:2012
4.
Discovery of a Potent Thiadiazole Class of Histamine H3 Receptor Antagonist for the Treatment of Diabetes
作者:
Ashwin U. Rao
;
Ning Shao
;
Robert G. Aslanian
;
Tin-Yau Chan
;
Sylvia J. Degrado
;
Li Wang
;
Brian
McKittrick
;
Mary Senior
;
Robert E. West
;
Jr.
;
Shirley M. Williams
;
Ren-Long Wu
;
Joyce Hwa
;
Bhuneshwari Patel
;
Shuqin Zheng
;
Christopher Sondey
;
Anandan Palani
刊名:ACS Medicinal Chemistry Letters
出版年:2012
5.
Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia
作者:
Anandan Palani
;
Ashwin U. Rao
;
Xiao Chen
;
Xianhai Huang
;
Jing Su
;
Haiqun Tang
;
Ying Huang
;
Jun Qin
;
Dong Xiao
;
Sylvia Degrado
;
Michael Sofolarides
;
Xiaohong Zhu
;
Zhidan Liu
;
Brian
McKittrick
;
Wei Zhou
;
Robert Aslanian
;
William J. Greenlee
;
Mary Senior
;
Boonlert Cheewatrakoolpong
;
Hongtao Zhang
;
Constance Farley
;
John Cook
;
Stan Kurowski
;
Qiu Li
;
Margaret van Heek
;
Gangfeng Wang
;
Yunsheng Hsieh
;
Fangbiao Li
;
Scott Greenfeder
;
Madhu Chintala
刊名:ACS Medicinal Chemistry Letters
出版年:2012
6.
Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation
作者:
Mihirbaran Mandal
;
Zhaoning Zhu
;
Jared N. Cumming
;
Xiaoxiang Liu
;
Corey Strickland
;
Robert D. Mazzola
;
John P. Caldwell
;
Prescott Leach
;
Michael Grzelak
;
Lynn Hyde
;
Qi Zhang
;
Giuseppe Terracina
;
Lili Zhang
;
Xia Chen
;
Reshma Kuvelkar
;
Matthew E. Kennedy
;
Leonard Favreau
;
Kathleen Cox
;
Peter Orth
;
Alexei Buevich
;
Johannes Voigt
;
Hongwu Wang
;
Irina Kazakevich
;
Brian
A.
McKittrick
;
William Greenlee
;
Eric M. Parker
;
Andrew W. Stamford
刊名:Journal of Medicinal Chemistry
出版年:2012
7.
Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel μM Leads for the Development of nM BACE-1 (β
作者:
Yu-Sen Wang
;
Corey Strickland
;
Johannes H. Voigt
;
Matthew E. Kennedy
;
Brian
M. Beyer
;
Mary M. Senior
;
Elizabeth M. Smith
;
Terry L. Nechuta
;
Vincent S. Madison
;
Michael Czarniecki
;
Brian
A.
McKittrick
刊名:Journal of Medicinal Chemistry
出版年:2010
8.
Discovery of Novel Hydroxamates as Highly Potent Tumor Necrosis Factor-α Converting Enzyme Inhibitors: Part IDiscovery of Two Binding Modes
作者:
Zhaoning Zhu
;
Robert Mazzola
;
Lisa Sinning
;
Brian
McKittrick
;
Xiaoda Niu
;
Daniel Lundell
;
Jing Sun
;
Peter Orth
;
Zhuyan Guo
;
Vincent Madison
;
Richard Ingram
;
Brian
M. Beyer
刊名:Journal of Medicinal Chemistry
出版年:2008
1
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