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馆藏书目(1)
CNKI学位论文(17)
知网期刊论文(4)
在“
ACS电子期刊
”中,
命中:
5
条,耗时:0.015989 秒
在所有数据库中总计命中:
22
条
1.
Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design
作者:
Christopher R. Butler
;
Michael A. Brodney
;
Elizabeth M. Bec
k
;
Gabriela Barreiro
;
Charles E. Nolan
;
Feng Pan
;
Felix Vajdos
;
K
evin Parris
;
Alison H. Varghese
;
Christopher J. Helal
;
Ricardo Lira
;
Shawn D. Doran
;
David R. Riddell
;
Leanne M. Buzon
;
Jason
K
.
Dutra
;
Luis A. Martinez-Alsina
;
K
evin Ogilvie
;
John C. Murray
;
Joseph M. Young
;
K
evin Atchison
;
Ashley Robshaw
;
Cathleen Gonzales
;
Jinlong Wang
;
Yong Zhang
;
Brian T. O鈥橬eill
刊名:Journal of Medicinal Chemistry
出版年:2015
2.
Stereoselective Synthesis of Spiropiperidines as BACE-1 Aspartyl Protease Inhibitors via Late Stage N-Arylation of a 1,8-Diazaspiro[4.5]dec-3-en-2-one Pharmacophore
作者:
Che-Wah Lee
;
Ricardo Lira
;
Jason
Dutra
;
K
evin Ogilvie
;
Brian T. O鈥橬eill
;
Michael Brodney
;
Christopher Helal
;
Joseph Young
;
Eri
k
Lachapelle
;
Subas Sa
k
ya
;
John C. Murray
刊名:The Journal of Organic Chemistry
出版年:2013
3.
Discovery and Optimization of a Novel Spiropyrrolidine Inhibitor of 尾-Secretase (BACE1) through Fragment-Based Drug Design
作者:
Ivan V. Efremov
;
Felix F. Vajdos
;
K
ris A. Borzilleri
;
Steven Capetta
;
Hou Chen
;
Peter H. Dorff
;
Jason
K
.
Dutra
;
Steven W. Goldstein
;
Mahmoud Mansour
;
Alexander McColl
;
Stephen Noell
;
Christine E. Obors
k
i
;
Thomas N. O鈥機onnell
;
Theresa J. O鈥橲ullivan
;
Jayvardhan Pandit
;
Hong Wang
;
BinQing Wei
;
Jane M. With
k
a
刊名:Journal of Medicinal Chemistry
出版年:2012
4.
Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active 纬-Secretase Inhibitor
作者:
Antonia F. Stepan
;
Cha
k
rapani Subramanyam
;
Ivan V. Efremov
;
Jason
K
.
Dutra
;
Theresa J. O鈥橲ullivan
;
K
enneth J. DiRico
;
W. Scott McDonald
;
Annie Won
;
Peter H. Dorff
;
Charles E. Nolan
;
Stacey L. Bec
k
er
;
Leslie R. Pustilni
k
;
David R. Riddell
;
Gregory W.
K
auffman
;
Bethany L.
K
ormos
;
Liming Zhang
;
Yasong Lu
;
Steven H. Capetta
;
Michael E. Green
;
K
apil Kar
k
i
;
Evelyn Sibley
;
K
evin P. Atchison
;
Andrew J. Hallgren
;
Christine E. Obors
k
i
;
Ashley E. Robshaw
;
Blossom Sneed
;
Christopher J. O鈥橠onnell
刊名:Journal of Medicinal Chemistry
出版年:2012
5.
Metabolism-Directed Design of Oxetane-Containing Arylsulfonamide Derivatives as 纬-Secretase Inhibitors
作者:
Antonia F. Stepan
;
K
apil Kar
k
i
;
W. Scott McDonald
;
Peter H. Dorff
;
Jason
K
.
Dutra
;
K
enneth J. DiRico
;
Annie Won
;
Cha
k
rapani Subramanyam
;
Ivan V. Efremov
;
Christopher J. O鈥橠onnell
;
Charles E. Nolan
;
Stacey L. Bec
k
er
;
Leslie R. Pustilni
k
;
Blossom Sneed
;
Hao Sun
;
Yasong Lu
;
Ashley E. Robshaw
;
David Riddell
;
Theresa J. O'Sullivan
;
Evelyn Sibley
;
Steven Capetta
;
K
evin Atchison
;
Andrew J. Hallgren
;
Emily Miller
;
Anthony Wood
;
R. Scott Obach
刊名:Journal of Medicinal Chemistry
出版年:2011
1
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