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在“ACS电子期刊”中，命中：9条，耗时：0.0179866 秒

在所有数据库中总计命中：19条

1.Pyridones as Highly Selective, Noncovalent Inhibitors of T790M Double Mutants of EGFR

作者：Marian C. Bryan ; Daniel J. Burdick ; Bryan K. Chan ; Yuan Chen ; Saundra Clausen ; Jennafer Dotson ; Charles Eigenbrot ; Richard Elliott ; Emily J. Hanan ; Robert Heald ; Philip Jackson ; Hank La ; Michael Lainchbury ; Shiva Malek ; Sam E. Mann ; Hans E. Purkey ; Gabriele Schaefer ; Stephen Schmidt ; Eileen Seward ; Steve Sideris ; Shumei Wang ; Ivana Yen ; Christine Yu ; Timothy P. Heffron

刊名：ACS Medicinal Chemistry Letters

出版年：2016

2.Correction to Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study

作者：Robert Heald ; Krista K. Bowman ; Marian C. Bryan ; Daniel Burdick ; Bryan Chan ; Emily Chan ; Yuan Chen ; Saundra Clausen ; Belen Dominguez-Fernandez ; Charles Eigenbrot ; Richard Elliott ; Emily J. Hanan ; Philip Jackson ; Jamie Knight ; Hank La ; Michael Lainchbury ; Shiva Malek ; Sam Mann ; Mark Merchant ; Kyle Mortara ; Hans Purkey ; Gabriele Schaefer ; Stephen Schmidt ; Eileen Seward ; Steve Sideris ; Lily Shao ; Shumei Wang ; Kuen Yeap ; Ivana Yen ; Christine Yu ; Timothy P. Heffron

刊名：Journal of Medicinal Chemistry

出版年：2016

3.Discovery of a Noncovalent, Mutant-Selective Epidermal Growth Factor Receptor Inhibitor

作者：Bryan K. Chan ; Emily J. Hanan ; Krista K. Bowman ; Marian C. Bryan ; Daniel Burdick ; Emily Chan ; Yuan Chen ; Saundra Clausen ; Trisha Dela Vega ; Jennafer Dotson ; Charles Eigenbrot ; Richard L. Elliott ; Robert A. Heald ; Philip S. Jackson ; Jamie D. Knight ; Hank La ; Michael D. Lainchbury ; Shiva Malek ; Hans E. Purkey ; Gabriele Schaefer ; Stephen Schmidt ; Eileen M. Seward ; Steve Sideris ; Lily Shao ; Shumei Wang ; Siew Kuen Yeap ; Ivana Yen ; Christine Yu ; Timothy P. Heffron

刊名：Journal of Medicinal Chemistry

出版年：2016

4.Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study

刊名：Journal of Medicinal Chemistry

出版年：2015

5.Discovery of Selective and Noncovalent Diaminopyrimidine-Based Inhibitors of Epidermal Growth Factor Receptor Containing the T790M Resistance Mutation

作者：Emily J. Hanan ; Charles Eigenbrot ; Marian C. Bryan ; Daniel J. Burdick ; Bryan K. Chan ; Yuan Chen ; Jennafer Dotson ; Robert A. Heald ; Philip S. Jackson ; Hank La ; Michael D. Lainchbury ; Shiva Malek ; Hans E. Purkey ; Gabriele Schaefer ; Stephen Schmidt ; Eileen M. Seward ; Steve Sideris ; Christine Tam ; Shumei Wang ; Siew Kuen Yeap ; Ivana Yen ; Jianping Yin ; Christine Yu ; Inna Zilberleyb ; Timothy P. Heffron

刊名：Journal of Medicinal Chemistry

出版年：2014

6.Discovery and Optimization of C-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2

作者：Mark Zak ; Rohan Mendonca ; Mercedesz Balazs ; Kathy Barrett ; Philippe Bergeron ; Wade S. Blair ; Christine Chang ; Gauri Deshmukh ; Jason DeVoss ; Peter S. Dragovich ; Charles Eigenbrot ; Nico Ghilardi ; Paul Gibbons ; Stefan Gradl ; Chris Hamman ; Emily J. Hanan ; Eric Harstad ; Peter R. Hewitt ; Christopher A. Hurley ; Tian Jin ; Adam Johnson ; Tony Johnson ; Jane R. Kenny ; Michael F. T. Koehler ; Pawan Bir Kohli ; Janusz J. Kulagowski ; Sharada Labadie ; Jiangpeng Liao ; Marya Liimatta ; Zhonghua Lin ; Patrick J. Lupardus ; Robert J. Maxey ; Jeremy M. Murray ; Rebecca Pulk ; Madeleine Rodriguez ; Scott Savage ; Steven Shia ; Micah Steffek ; Savita Ubhayakar ; Mark Ultsch ; Anne van Abbema ; Stuart I. Ward ; Ling Xiao ; Yisong Xiao

刊名：Journal of Medicinal Chemistry

出版年：2012

7.Discovery and Development of Potent LFA-1/ICAM-1 Antagonist SAR 1118 as an Ophthalmic Solution for Treating Dry Eye

作者：Min Zhong ; Thomas R. Gadek ; Minna Bui ; Wang Shen ; John Burnier ; Kenneth J. Barr ; Emily J. Hanan ; Johan D. Oslob ; Chul H. Yu ; Jiang Zhu ; Michelle R. Arkin ; Marc J. Evanchik ; W. Mike Flanagan ; Ute Hoch ; Jennifer Hyde ; Saileta Prabhu ; Jeffrey A. Silverman ; Jasmin Wright

刊名：ACS Medicinal Chemistry Letters

出版年：2012

8.Discovery of Potent and Selective Pyrazolopyrimidine Janus Kinase 2 Inhibitors

作者：Emily J. Hanan ; Anne van Abbema ; Kathy Barrett ; Wade S. Blair ; Jeff Blaney ; Christine Chang ; Charles Eigenbrot ; Sean Flynn ; Paul Gibbons ; Christopher A. Hurley ; Jane R. Kenny ; Janusz Kulagowski ; Leslie Lee ; Steven R. Magnuson ; Claire Morris ; Jeremy Murray ; Richard M. Pastor ; Tom Rawson ; Michael Siu ; Mark Ultsch ; Aihe Zhou ; Deepak Sampath ; Joseph P. Lyssikatos

刊名：Journal of Medicinal Chemistry

出版年：2012

9.Insights into the Structural Determinants Required for High-Affinity Binding of Chiral Cyclopropane-Containing Ligands to 伪4尾2-Nicotinic Acetylcholine Receptors: An Integrated Approach to Behaviorally

作者：Han-Kun Zhang ; J. Brek Eaton ; Li-Fang Yu ; Mieke Nys ; Angelica Mazzolari ; Ren茅 van Elk ; August B. Smit ; Vadim Alexandrov ; Taleen Hanania ; Emily Sabath ; Allison Fedolak ; Daniela Brunner ; Ronald J. Lukas ; Giulio Vistoli ; Chris Ulens ; Alan P. Kozikowski

刊名：Journal of Medicinal Chemistry

出版年：2012

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按出版年细分(9)

2016年(3)

2015年(1)

2014年(1)

2012年(4)