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内部出版物
在“
SpringerLink电子期刊
”中,
命中:
128
条,耗时:小于0.01 秒
1.
Structural exploration of PPARγ modulators through pharmacophore mapping, fragment-based design, docking, and molecular dynamics simulation analyses
作者:
Ashis Nandy
;
Kunal Roy
;
Achintya Saha
关键词:
Type 2 diabetes mellitus (T2DM)
;
PPARγ
;
Ligand
;
based pharmacophore
e ;
pharmacophore
;
HQSAR
;
Bayesian model
;
Molecular dynamics
刊名:Medicinal Chemistry Research
出版年:2017
2.
Hybrids: a new paradigm to treat Alzheimer’s disease
作者:
Manjinder Singh
;
Maninder Kaur
;
Navriti Chadha
;
Om Silakari
关键词:
Acetylcholinesterase inhibitors
;
Hybrids
;
Multi
;
target
;
Alzheimer’s disease
;
Tacrine
;
$$\beta $$ β
;
Amyloid
刊名:Molecular Diversity
出版年:2016
3.
Per-Residue Energy Footprints-Based Pharmacophore Modeling as an Enhanced In Silico Approach in Drug Discovery: A Case Study on the Identification of Novel β-Secretase1 (BACE1) Inhibitors as Anti-Alzheimer Agents
作者:
H. M. Kumalo
;
Mahmoud E. Soliman
关键词:
Alzheimer disease (AD) per
;
residue energy footprints
;
based docking molecular dynamics pharmacophore model
;
β
;
Secretase
;
Virtual screening
;
Protocol
刊名:Cellular and Molecular Bioengineering
出版年:2016
4.
Identification of novel inhibitors for Pim-1 kinase using pharmacophore modeling based on a novel method for selecting pharmacophore generation subsets
作者:
Rand Shahin
;
Lubna Swellmeen
;
Omar Shaheen…
关键词:
Pim 1 kinase
;
QSAR
;
Ligand base
;
Pharmacophore modelling
;
Discovery studio
刊名:Journal of Computer-Aided Molecular Design
出版年:2016
5.
Discovery of novel drug targets and their functions using phenotypic screening of natural products
作者:
Junghwa Chang
;
Ho Jeong Kwon
关键词:
Natural products
;
Phenotypic screening
;
Target identification
;
Mode of action
;
Drug discovery
刊名:Journal of Industrial Microbiology and Biotechnology
出版年:2016
6.
Discovery of new coumarin substituted quinazolines as potential bioactive agents
作者:
Amit B. Patel
;
Rinku M. Raval
关键词:
Quinazoline
;
Coumarin
;
Benzothiazole
;
Antimicrobial
;
Antimycobacterial activity
刊名:Research on Chemical Intermediates
出版年:2016
7.
Effects of the Hybridization of Opioid and Neurotensin
Pharmacophores
on Cell Survival in Rat Organotypic Hippocampal Slice Cultures
作者:
Patrycja Kleczkowska
;
Maria Kawalec
;
Magdalena Bujalska-Zadrozny…
关键词:
Hippocampus
;
Hybrid peptide
;
Neurotensin
;
Opioid
;
Neurotoxicity
刊名:Neurotoxicity Research
出版年:2015
8.
A review on pharmacophoric designs of antiproliferative agents
作者:
Anil Rana (1)
Jimi Marin Alex (1)
Monika Chauhan (1)
Gaurav Joshi (1)
Raj Kumar (1)
1. Laboratory for Drug Design and Synthesis
;
Centre for Chemical and Pharmaceutical Sciences
;
School of Basic and Applied Sciences
;
Central University of Punjab
;
CUPB Library Communication No. P48/14
;
Bathinda
;
151 001
;
Punjab
;
India
关键词:
Cancer
;
Pharmacophores
;
Anti
;
proliferative agents
;
Dual inhibitors
;
Multi inhibitors
刊名:Medicinal Chemistry Research
出版年:2015
9.
6-(4-Amino-2-butyl-imidazoquinolyl)-norleucine: Toll-like receptor 7 and 8 agonist amino acid for self-adjuvanting peptide vaccine
作者:
Yoshio Fujita
;
Kazuyuki Hirai
;
Keigo Nishida
;
Hiroaki Taguchi
刊名:Amino Acids
出版年:2016
10.
ILP-assisted de novo drug design
作者:
Rama Kaalia
;
Ashwin Srinivasan
;
Amit Kumar
;
Indira Ghosh
刊名:Machine Learning
出版年:2016
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