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知网期刊论文(5796)
在“
SpringerLink电子期刊
”中,
命中:
851
条,耗时:0.0489756 秒
在所有数据库中总计命中:
21,074
条
1.
Studying neuroprotective effect of Atorvastatin as a
small
molecule
drug on high glucose-induced neurotoxicity in undifferentiated PC12 cells: role of NADPH oxidase
作者:
Samira Rayegan
;
Ahmad Reza Dehpour
;
Ali Mohammad Sharifi
关键词:
Atorvastatin
;
High glucose
;
NADPH oxidase
;
Oxidative stress
;
PC12 cells
刊名:Metabolic Brain Disease
出版年:2017
2.
Discovery of novel
small
molecule
EGFR
inhibitor
y leads by structure and ligand-based virtual screening
作者:
Priya Mahajan
;
Nitasha Suri
;
Rukmankesh Mehra
;
Monika Gupta…
关键词:
Epidermal growth factor receptor
inhibitor
s
;
Virtual screening
;
Pharmacophore modeling
;
QSAR
刊名:Medicinal Chemistry Research
出版年:2017
3.
Benzimidazole
inhibitor
s of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1
作者:
Konrad Kubiński
;
Maciej Masłyk
;
Andrzej Orzeszko
关键词:
Protein kinases
;
Small
;
molecule
inhibitor
s
;
Competitive inhibition
;
Toyocamycin
;
TIBI
刊名:Molecular and Cellular Biochemistry
出版年:2017
4.
Computational identification of novel entry
inhibitor
scaffolds mimicking primary receptor CD4 of HIV-1 gp120
作者:
Alexander M. Andrianov
;
Ivan A. Kashyn…
关键词:
Cellular receptor CD4
;
HIV
;
1 gp120 protein
;
Molecular docking
;
Molecular dynamics
;
Peptidomimetics
;
Small
molecule
CD4
;
antagonists
;
Virtual screening
刊名:Journal of Molecular Modeling
出版年:2017
5.
Toxicity and anti-angiogenicity evaluation of Pak1
inhibitor
IPA-3 using zebrafish embryo model
作者:
Sankar Jagadeeshan
;
R. Vivek Sagayaraj
;
Navina Paneerselvan…
关键词:
Anti
;
angiogenesis
;
Pak1
;
IPA
3 ;
VEGF
;
Toxicity
;
Zebrafish embryos
刊名:Cell Biology and Toxicology
出版年:2017
6.
Targeting the protein ubiquitination machinery in melanoma by the NEDD8-activating enzyme
inhibitor
pevonedistat (MLN4924)
作者:
Kit Man Wong
;
Lindsey N. Micel
;
Heather M. Selby…
关键词:
Neddylation
;
Pevonedistat
;
MLN4924
;
Protein degradation
;
Melanoma
刊名:Investigational New Drugs
出版年:2017
7.
Emerging biologics in inflammatory bowel disease
作者:
Heyson Chi-hey Chan
;
Siew Chien Ng
关键词:
Crohn’s disease
;
Ulcerative colitis
;
Biologics
;
Biosimilar
刊名:Journal of Gastroenterology
出版年:2017
8.
Chemotherapeutic drug selectivity between wild-type and mutant BRaf kinases in colon cancer
作者:
Jianchun Zhang
;
Tao Ji
关键词:
Activation loop
;
BRaf kinase
;
Chemotherapeutic drug
;
Colon cancer
;
Phosphorylation
刊名:Journal of Molecular Modeling
出版年:2017
9.
Synthesis and Stability of Hydroxyfasudil Derivatives as Prodrugs
作者:
Yang Li
;
Na Liu
;
Hao Luo
;
Yanyan Yuan
;
Yuzhi Xing…
关键词:
Hydroxyfasudil
;
Prodrugs
;
Rho
;
kinase
;
Fasudil
;
Stability
刊名:Transactions of Tianjin University
出版年:2017
10.
Pharmacokinetics, Pharmacodynamics, and Safety of Entospletinib, a Novel pSYK
Inhibitor
, Following Single and Multiple Oral Dosing in Healthy Volunteers
作者:
Srini Ramanathan
;
Julie A. Di Paolo
;
Feng Jin
;
Lixin Shao…
刊名:Clinical Drug Investigation
出版年:2017
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