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在“NATURE电子期刊”中，命中：6,541条，耗时：小于0.01 秒

在所有数据库中总计命中：72条

1.Correlating chemical sensitivity and basal gene expression reveals mechanism of action

作者：Matthew G Rees ; Brinton Seashore-Ludlow ; Jaime H Cheah ; Drew J Adams ; Edmund V Price ; Shubhroz Gill ; Sarah Javaid ; Matthew E Coletti ; Victor L Jones ; Nicole E Bodycombe ; Christian K Soule ; Benjamin Alexander ; Ava Li ; Philip Montgomery ; Joanne D Kotz ; C Suk-Yee Hon ; Benito Munoz ; Ted Liefeld ; Vlado Dančík ; Daniel A Haber ; Clary B Clish ; Joshua A Bittker ; Michelle Palmer ; Bridget K Wagner ; Paul A Clemons ; Alykhan F Shamji ; Stuart L Schreiber

关键词：Mechanism of action ; Target identification ; Cancer therapy ; Small molecules

刊名：Nature Chemical Biology

出版年：2016

2.Chemical probes: The many genes of drug mechanism

作者：Adam C Palmer

关键词：Mechanism of action ; Small molecules ; Cancer ; Databases

刊名：Nature Chemical Biology

出版年：2016

3.Molecular mechanism of respiratory syncytial virus fusion inhibitors

作者：Michael B Battles ; Johannes P Langedijk ; Polina Furmanova-Hollenstein ; Supranee Chaiwatpongsakorn ; Heather M Costello ; Leen Kwanten ; Luc Vranckx ; Paul Vink ; Steffen Jaensch ; Tim H M Jonckers ; Anil Koul ; Eric Arnoult ; Mark E Peeples ; Dirk Roymans ; Jason S McLellan

关键词：Infectious diseases ; X-ray crystallography ; Virology ; Structure-based drug design ; Mechanism of action

刊名：Nature Chemical Biology

出版年：2016

4.Cooperation of local motions in the Hsp90 molecular chaperone ATPase mechanism

作者：Andrea Schulze ; Gerti Beliu ; Dominic A Helmerich ; Jonathan Schubert ; Laurence H Pearl ; Chrisostomos Prodromou ; Hannes Neuweiler

关键词：Proteins ; Single-molecule biophysics ; Protein folding ; Imaging

刊名：Nature Chemical Biology

出版年：2016

5.A simple physical mechanism enables homeostasis in primitive cells

作者：Aaron E. Engelhart ; Katarzyna P. Adamala ; Jack W. Szostak

关键词：Chemistry ; RNA ; Enzymes ; RNA ; Self-assembly

刊名：Nature Chemistry

出版年：2016

6.Carbon dioxide transport in molten calcium carbonate occurs through an oxo-Grotthuss mechanism via a pyrocarbonate anion

作者：Dario Corradini ; Franç ; ois-Xavier Coudert ; Rodolphe Vuilleumier

关键词：Chemical physics ; Density functional theory ; Molecular dynamics

刊名：Nature Chemistry

出版年：2016

7.A two-state activation mechanism controls the histone methyltransferase Suv39h1

作者：Manuel M Mü ; ller ; Beat Fierz ; Lenka Bittova ; Glen Liszczak ; Tom W Muir

关键词：Post-translational modifications ; Biochemistry ; Enzymes

刊名：Nature Chemical Biology

出版年：2016

8.A phosphoinositide conversion mechanism for exit from endosomes

作者：Katharina Ketel ; Michael Krauss ; Anne-Sophie Nicot ; Dmytro Puchkov ; Marnix Wieffer ; Rainer Mü ; ller ; Devaraj Subramanian ; Carsten Schultz ; Jocelyn Laporte ; Volker Haucke

关键词：Endosomes ; Mechanisms of disease ; Exocytosis ; Phospholipids

刊名：Nature

出版年：2016

9.The mechanism of RNA 5′ capping with NAD+, NADH and desphospho-CoA

作者：Jeremy G. Bird ; Yu Zhang ; Yuan Tian ; Natalya Panova ; Ivan Barvík ; Landon Greene ; Min Liu ; Brian Buckley ; Libor Krá ; sný ; Jeehiun K. Lee ; Craig D. Kaplan ; Richard H. Ebright ; Bryce E. Nickels

关键词：X-ray crystallography ; RNA modification ; Transcription ; RNA

刊名：Nature

出版年：2016

10.X-ray structures and mechanism of the human serotonin transporter

作者：Jonathan A. Coleman ; Evan M. Green ; Eric Gouaux

关键词：X-ray crystallography ; Membrane proteins ; Transporters in the nervous system

刊名：Nature

出版年：2016

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