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NATURE电子期刊(1)
Elsevier电子期刊(1)
ACS电子期刊(8)
在“
ACS电子期刊
”中,
命中:
8
条,耗时:小于0.01 秒
在所有数据库中总计命中:
10
条
1.
GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile
作者:
Elisia Villemure
;
Matthew Volgraf
;
Yu Jiang
;
Guosheng Wu
;
Cuong Q. Ly
;
Po-wai Yuen
;
Aijun Lu
;
Xifeng Luo
;
Mingcui Liu
;
Shun Zhang
;
Patrick J. Lupardus
;
Heidi J. A. Wallweber
;
Bianca M. Liederer
;
Gauri Deshmukh
;
Emile
Plise
;
Suzanne Tay
;
Tzu-Ming Wang
;
Jesse E. Hanson
;
David H. Hackos
;
Kimberly Scearce-Levie
;
Jacob B. Schwarz
;
Benjamin D. Sellers
刊名:ACS Medicinal Chemistry Letters
出版年:2017
2.
Discovery of Clinical Development Candidate GDC-0084, a Brain Penetrant Inhibitor of PI3K and mTOR
作者:
Timothy P. Heffron
;
Chudi O. Ndubaku
;
Laurent Salphati
;
Bruno Alicke
;
Jonathan Cheong
;
Joy Drobnick
;
Kyle Edgar
;
Stephen E. Gould
;
Leslie B. Lee
;
John D. Lesnick
;
Cristina Lewis
;
Jim Nonomiya
;
Jodie Pang
;
Emile
G.
Plise
;
Steve Sideris
;
Jeffrey Wallin
;
Lan Wang
;
Xiaolin Zhang
;
Alan G. Olivero
刊名:ACS Medicinal Chemistry Letters
出版年:2016
3.
Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design
作者:
Matthew Volgraf
;
Benjamin D. Sellers
;
Yu Jiang
;
Guosheng Wu
;
Cuong Q. Ly
;
Elisia Villemure
;
Richard M. Pastor
;
Po-wai Yuen
;
Aijun Lu
;
Xifeng Luo
;
Mingcui Liu
;
Shun Zhang
;
Liang Sun
;
Yuhong Fu
;
Patrick J. Lupardus
;
Heidi J.A. Wallweber
;
Bianca M. Liederer
;
Gauri Deshmukh
;
Emile
Plise
;
Suzanne Tay
;
Paul Reynen
;
James Herrington
;
Amy Gustafson
;
Yichin Liu
;
Akim Dirksen
;
Matthias G. A. Dietz
;
Yanzhou Liu
;
Tzu-Ming Wang
;
Jesse E. Hanson
;
David Hackos
;
Kimberly Scearce-Levie
;
Jacob B. Schwarz
刊名:Journal of Medicinal Chemistry
出版年:2016
4.
Role of P-Glycoprotein on the Brain Penetration and Brain Pharmacodynamic Activity of the MEK Inhibitor Cobimetinib
作者:
Edna F. Choo
;
Justin Ly
;
Jocelyn Chan
;
Sheerin K. Shahidi-Latham
;
Kirsten Messick
;
Emile
Plise
;
Cristine M. Quiason
;
Lulu Yang
刊名:Molecular Pharmaceutics
出版年:2014
5.
Evaluating the In Vitro Inhibition of UGT1A1, OATP1B1, OATP1B3, MRP2, and BSEP in Predicting Drug-Induced Hyperbilirubinemia
作者:
Jae H. Chang
;
Emile
Plise
;
Jonathan Cheong
;
Quynh Ho
;
Molly Lin
刊名:Molecular Pharmaceutics
出版年:2013
6.
Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)
作者:
John A. Flygare
;
Maureen Beresini
;
Nageshwar Budha
;
Helen Chan
;
Iris T. Chan
;
Sravanthi Cheeti
;
Frederick Cohen
;
Kurt Deshayes
;
Karl Doerner
;
S. Gail Eckhardt
;
Linda O. Elliott
;
Bainian Feng
;
Matthew C. Franklin
;
Stacy Frankovitz Reisner
;
Lewis Gazzard
;
Jason Halladay
;
Sarah G. Hymowitz
;
Hank La
;
Patricia LoRusso
;
Brigitte Maurer
;
Lesley Murray
;
Emile
Plise
;
Clifford Quan
;
Jean-Philippe Stephan
;
Shin G. Young
;
Jeffrey Tom
;
Vickie Tsui
;
Joanne Um
;
Eugene Varfolomeev
;
Domagoj Vucic
;
Andrew J. Wagner
;
Heidi J. A. Wallweber
;
Lan Wang
;
Joseph Ware
;
Zhaoyang Wen
;
Harvey Wong
;
Jonathan M. Wong
;
Melisa Wong
;
Susan Wong
;
Ron Yu
;
Kerry Zobel
;
Wayne J. Fairbrother
刊名:Journal of Medicinal Chemistry
出版年:2012
7.
The Design and Identification of Brain Penetrant Inhibitors of Phosphoinositide 3-Kinase 伪
作者:
Timothy P. Heffron
;
Laurent Salphati
;
Bruno Alicke
;
Jonathan Cheong
;
Jennafer Dotson
;
Kyle Edgar
;
Richard Goldsmith
;
Stephen E. Gould
;
Leslie B. Lee
;
John D. Lesnick
;
Cristina Lewis
;
Chudi Ndubaku
;
Jim Nonomiya
;
Alan G. Olivero
;
Jodie Pang
;
Emile
G.
Plise
;
Steve Sideris
;
Sean Trapp
;
Jeffrey Wallin
;
Lan Wang
;
Xiaolin Zhang
刊名:Journal of Medicinal Chemistry
出版年:2012
8.
Identification, Characterization, and Implications of Species-Dependent Plasma Protein Binding for the Oral Hedgehog Pathway Inhibitor Vismodegib (GDC-0449)
作者:
Anthony M. Giannetti
;
Harvey Wong
;
Gerrit J. P. Dijkgraaf
;
Erin C. Dueber
;
Daniel F. Ortwine
;
Brandon J. Bravo
;
Stephen E. Gould
;
Emile
G.
Plise
;
Bert L. Lum
;
Vikram Malhi
;
Richard A. Graham
刊名:Journal of Medicinal Chemistry
出版年:2011
1
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