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在“ACS电子期刊”中，命中：4条，耗时：小于0.01 秒

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1.Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy

作者：Kimberly O. Cameron ; Daniel W. Kung ; Amit S. Kalgutkar ; Ravi G. Kurumbail ; Russell Miller ; Christopher T. Salatto ; Jessica Ward ; Jane M. Withka ; Samit K. Bhattacharya ; Markus Boehm ; Kris A. Borzilleri ; Janice A. Brown ; Matthew Calabrese ; Nicole L. Caspers ; Emily Cokorinos ; Edward L. Conn ; Matthew S. Dowling ; David J. Edmonds ; Heather Eng ; Dilinie P. Fernando ; Richard Frisbie ; David Hepworth ; James Landro ; Yuxia Mao ; Francis Rajamohan ; Allan R. Reyes ; Colin R. Rose ; Tim Ryder ; Andre Shavnya ; Aaron C. Smith ; Meihua Tu ; Angela C. Wolford ; Jun Xiao

刊名：Journal of Medicinal Chemistry

出版年：2016

2.Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Car

作者：Roger B. Ruggeri ; Leonard Buckbinder ; Scott W. Bagley ; Philip A. Carpino ; Edward L. Conn ; Matthew S. Dowling ; Dilinie P. Fernando ; Wenhua Jiao ; Daniel W. Kung ; Suvi T. M. Orr ; Yingmei Qi ; Benjamin N. Rocke ; Aaron Smith ; Joseph S. Warmus ; Yan Zhang ; Daniel Bowles ; Daniel W. Widlicka ; Heather Eng ; Tim Ryder ; Raman Sharma ; Angela Wolford ; Carlin Okerberg ; Karen Walters ; Tristan S. Maurer ; Yanwei Zhang ; Paul D. Bonin ; Samantha N. Spath ; Gang Xing ; David Hepworth ; Kay Ahn ; Amit S. Kalgutkar

刊名：Journal of Medicinal Chemistry

出版年：2015

3.Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists

作者：David W. Piotrowski ; Kentaro Futatsugi ; Joseph S. Warmus ; Suvi T. M. Orr ; Kevin D. Freeman-Cook ; Allyn T. Londregan ; Liuqing Wei ; Sandra M. Jennings ; Michael Herr ; Steven B. Coffey ; Wenhua Jiao ; Gregory Storer ; David Hepworth ; Jian Wang ; Sophie Y. Lavergne ; Janice E. Chin ; John R. Hadcock ; Martin B. Brenner ; Angela C. Wolford ; Ann M. Janssen ; Nicole S. Roush ; Joanne Buxton ; Terri Hinchey ; Amit S. Kalgutkar ; Raman Sharma ; Declan A. Flynn

刊名：ACS Medicinal Chemistry Letters

出版年：2013

4.Oxidative Metabolism of a Quinoxaline Derivative by Xanthine Oxidase in Rodent Plasma

作者：Raman Sharma ; Heather Eng ; Gregory S. Walker ; Gabriela Barreiro ; Antonia F. Stepan ; Kim F. McClure ; Angela Wolford ; Paul D. Bonin ; Peter Cornelius ; Amit S. Kalgutkar

刊名：Chemical Research in Toxicology

出版年：2011

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