设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
Elsevier电子期刊(57)
ACS电子期刊(19)
在“
ACS电子期刊
”中,
命中:
19
条,耗时:0.03695 秒
在所有数据库中总计命中:
76
条
1.
D
e
v
e
lopm
e
nt of 4-H
e
t
e
roarylamino-1′-azaspiro[oxazol
e
-5,3′-bicyclo[2.2.2]octan
e
s] as α7 Nicotinic R
e
c
e
ptor Agonists
作者:
Matth
e
w D. HillHaiquan Fang
;
H. Dalton King
;
Christiana I. Iwuagwu
;
Ivar M. McDonald
;
Jam
e
s Cook
;
F. Christoph
e
r ZusiRob
e
rt A. Mat
e
;
Ronald J. Knox
;
D
e
bra Post-Munson
;
Amy
E
aston
;
R
e
gina Mill
e
r
;
Kimb
e
rl
e
y L
e
ntz
;
W
e
ndy Clark
e
;
Yulia B
e
nit
e
x
;
Nicholas Lodg
e
;
Rob
e
rt Zacz
e
k
;
R
e
x D
e
nton
;
Dani
e
l Morgan
;
Linda Bristow
;
John
E
.
Macor
;
Richard Olson
刊名:ACS M
e
dicinal Ch
e
mistry L
e
tt
e
rs
出版年:2017
2.
Targ
e
ting th
e
BACE1 Activ
e
Sit
e
Flap L
e
ads to a Pot
e
nt Inhibitor That Elicits Robust Brain Aβ R
e
duction in Rod
e
nts
作者:
Yong-Jin Wu
;
Jason Gu
e
rnon
;
Fukang Yang
;
Lawr
e
nc
e
Snyd
e
r
;
Jianliang Shi
;
Andr
e
a Mcclur
e
;
Ramkumar Rajamani
;
Hyunsoo Park
;
Alicia Ng
;
Hal L
e
wis
;
Chi
e
hYing Chang
;
Dan Camac
;
J
e
r
e
my H. Toyn
;
Micha
e
l K. Ahlijanian
;
Charl
e
s F. Albright
;
John
E
.
Macor
;
Lorin A. Thompson
刊名:ACS M
e
dicinal Ch
e
mistry L
e
tt
e
rs
出版年:2016
3.
D
e
sign and Synth
e
sis of a N
e
w S
e
ri
e
s of 4-H
e
t
e
roarylamino-1′-azaspiro[oxazol
e
-5,3′-bicyclo[2.2.2]octan
e
s as α7 Nicotinic R
e
c
e
ptor Agonists. 1. D
e
v
e
lopm
e
nt of Pharmacophor
e
and Early Structur
e
–Activity R
e
lationship
作者:
Jam
e
s CookF. Christoph
e
r Zusi
;
Ivar M. McDonald
;
Dalton King
;
Matth
e
w D. Hill
;
Christiana Iwuagwu
;
Rob
e
rt A. Mat
e
;
Haiquan Fang
;
Rulin Zhao
;
B
e
i Wang
;
Jingfang Cutron
e
;
Baoqing Ma
;
Qi Gao
;
Ronald J. Knox
;
Mich
e
l
e
Match
e
tt
;
Lizb
e
th Gallagh
e
r
;
M
e
r
e
dith F
e
rrant
e
;
D
e
bra Post-Munson
;
Thadd
e
us Molski
;
Amy
E
aston
;
R
e
gina Mill
e
r
;
K
e
lli Jon
e
s
;
Siva Digavalli
;
Francin
e
H
e
aly
;
Kimb
e
rl
e
y L
e
ntz
;
Yulia B
e
nit
e
x
;
W
e
ndy Clark
e
;
Joann
e
Natal
e
;
Judith A. Siuciak
;
Nicholas Lodg
e
;
Rob
e
rt Zacz
e
k
;
R
e
x D
e
nton
;
Dani
e
l Morgan
;
Linda J. Bristow
;
John
E
.
Macor
;
Richard
E
. Olson
刊名:Journal of M
e
dicinal Ch
e
mistry
出版年:2016
4.
Discov
e
ry and Pr
e
clinical Evaluation of BMS-955829, a Pot
e
nt Positiv
e
Allost
e
ric Modulator of mGluR5
作者:
Fukang Yang
;
Lawr
e
nc
e
B. Snyd
e
r
;
Anand Balakrishnan
;
J
e
ffr
e
y M. Brown
;
Digavalli V. Sivarao
;
Amy
E
aston
;
Alda F
e
rnand
e
s
;
Micha
e
l Gulian
e
llo
;
Um
e
sh M. Hanum
e
gowda
;
Hong Huang
;
Yanling Huang
;
K
e
lli M. Jon
e
s
;
Yu-W
e
n Li
;
Mich
e
l
e
Match
e
tt
;
Gail Mattson
;
R
e
gina Mill
e
r
;
K
e
nn
e
th S. Santon
e
;
Arun S
e
napati
;
E
ric E. Shi
e
lds
;
Frank J. Simutis
;
Ryan W
e
stphal
;
Val
e
ri
e
J. Whit
e
rock
;
Joann
e
J. Bronson
;
John
E
.
Macor
;
Andr
e
w P. D
e
gnan
刊名:ACS M
e
dicinal Ch
e
mistry L
e
tt
e
rs
出版年:2016
5.
D
e
v
e
lopm
e
nt of 1H-Pyrazolo[3,4-b]pyridin
e
s as M
e
tabotropic Glutamat
e
R
e
c
e
ptor 5 Positiv
e
Allost
e
ric Modulators
作者:
Matth
e
w D. Hill
;
Haiquan Fang
;
J
e
ffr
e
y M. Brown
;
Thadd
e
us Molski
;
Amy
E
aston
;
Xiaojun Han
;
R
e
gina Mill
e
r
;
M
e
lissa Hill-Drz
e
wi
;
Lizb
e
th Gallagh
e
r
;
Mich
e
l
e
Match
e
tt
;
Micha
e
l Gulian
e
llo
;
Anand Balakrishnan
;
Rob
e
rt L. B
e
rt
e
kap
;
K
e
nn
e
th S. Santon
e
;
Val
e
ri
e
J. Whit
e
rock
;
Xiaoliang Zhuo
;
Joann
e
J. Bronson
;
John
E
.
Macor
;
Andr
e
w P. D
e
gnan
刊名:ACS M
e
dicinal Ch
e
mistry L
e
tt
e
rs
出版年:2016
6.
Discov
e
ry of S3-Truncat
e
d, C-6 H
e
t
e
roaryl Substitut
e
d Aminothiazin
e
β-Sit
e
APP Cl
e
aving Enzym
e
-1 (BACE1) Inhibitors
作者:
Yong-Jin Wu
;
Jason Gu
e
rnon
;
Jianliang Shi
;
Lawr
e
nc
e
Marcin
;
M
e
ndi Higgins
;
Ramkumar Rajamani
;
Jodi Muck
e
lbau
e
r
;
Hal L
e
wis
;
Chi
e
hYing Chang
;
Dan Camac
;
J
e
r
e
my H. Toyn
;
Micha
e
l K. Ahlijanian
;
Charl
e
s F. Albright
;
John
E
.
Macor
;
Lorin A. Thompson
刊名:Journal of M
e
dicinal Ch
e
mistry
出版年:2016
7.
Discov
e
ry of Indazol
e
s as Pot
e
nt, Orally Activ
e
Dual N
e
urokinin 1 R
e
c
e
ptor Antagonists and S
e
rotonin Transport
e
r Inhibitors for th
e
Tr
e
atm
e
nt of D
e
pr
e
ssion
作者:
Andr
e
w P. D
e
gnan
;
G
e
org
e
O. Tora
;
Hong Huang
;
David A. Conlon
;
Carl D. Davis
;
Um
e
sh M. Hanum
e
gowda
;
Xiaoping Hou
;
Yi Hsiao
;
Joanna Hu
;
Rudolph Kraus
e
;
Yu-W
e
n Li
;
Amy
E
. N
e
wton
;
Rick L. Pi
e
schl
;
Jos
e
ph Raybon
;
Thorst
e
n Rosn
e
r
;
Jung-Hui Sun
;
Matth
e
w T. Tab
e
r
;
Sarah J. Taylor
;
Micha
e
l K. Wong
;
Huiping Zhang
;
Nicholas J. Lodg
e
;
Joann
e
J. Bronson
;
John
E
.
Macor
;
K
e
vin W. Gillman
刊名:ACS Ch
e
mical N
e
urosci
e
nc
e
出版年:2016
8.
Discov
e
ry of Isonicotinamid
e
s as Highly S
e
l
e
ctiv
e
, Brain P
e
n
e
trabl
e
, and Orally Activ
e
Glycog
e
n Synthas
e
Kinas
e
-3 Inhibitors
作者:
Guanglin Luo
;
Ling Ch
e
n
;
Cath
e
rin
e
R. Burton
;
Hong Xiao
;
Prasanna Sivaprakasam
;
Carol M. Kraus
e
;
Yang Cao
;
N
e
ngyin Liu
;
Jonathan Lippy
;
W
e
ndy J. Clark
e
;
Kimb
e
rly Snow
;
Jos
e
ph Raybon
;
Vinod Arora
;
Matt Pokross
;
K
e
vin Kish
;
Hal A. L
e
wis
;
David R. Langl
e
y
;
John
E
.
Macor
;
G
e
n
e
M. Dubowchik
刊名:Journal of M
e
dicinal Ch
e
mistry
出版年:2016
9.
Discov
e
ry, Synth
e
sis, and Pr
e
clinical Charact
e
rization of N-(3-Chloro-4-fluoroph
e
nyl)-1H-pyrazolo[4,3-b]pyridin-3-amin
e
(VU0418506), a Nov
e
l Positiv
e
Allost
e
ric Modulator of th
e
M
e
tabotropic Glutamat
e
R
e
c
e
ptor 4 (mGlu4)
作者:
Darr
e
n W. Eng
e
rs
;
Anna L. Blobaum
;
Rocco D. Gogliotti
;
Yiu-Yin Ch
e
ung
;
Jam
e
s M. Salovich
;
P
e
dro M. Garcia-Barrant
e
s
;
J. Scott Dani
e
ls
;
Ryan Morrison
;
Carri
e
K. Jon
e
s
;
Matth
e
w G. Soars
;
Xiaoliang Zhuo
;
J
e
r
e
my Hurl
e
y
;
John
E
.
Macor
;
Joann
e
J. Bronson
;
P. J
e
ffr
e
y Conn
;
Craig W. Lindsl
e
y
;
Coll
ee
n M. Nisw
e
nd
e
r
;
Cor
e
y R. Hopkins
刊名:ACS Ch
e
mical N
e
urosci
e
nc
e
出版年:2016
10.
Asymm
e
tric Synth
e
sis of H
e
t
e
rocyclic Analogu
e
s of a CGRP R
e
c
e
ptor Antagonist for Tr
e
ating Migrain
e
作者:
Guanglin Luo
;
Ling Ch
e
n
;
Charl
e
s M. Conway
;
Walt
e
r Kostich
;
John
E
.
Macor
;
G
e
n
e
M. Dubowchik
刊名:Organic L
e
tt
e
rs
出版年:2015
1
2
按检索点细分(19)
题名(17)
关键词(1)
按出版年细分(19)
2017年(1)
2016年(8)
2015年(1)
2014年(1)
2012年(3)
2011年(1)
2009年(1)
2008年(1)
2004年(1)
2000年及以前(1)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.