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SpringerLink电子期刊(7)
Elsevier电子期刊(32)
ACS电子期刊(17)
在“
ACS电子期刊
”中,
命中:
17
条,耗时:小于0.01 秒
在所有数据库中总计命中:
56
条
1.
Discovery and in Vivo Evaluation of the Potent and Selective PI3Kδ Inhibitors 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-0687) and 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-5-fluoro-N-methyl-3-(2-pyridinyl)-4-quino
作者:
Felix Gonzalez-Lopez de Turiso
;
Xiaolin Hao
;
Youngsook Shin
;
Minna Bui
;
Iain D. G. Campuzano
;
Mario Cardozo
;
Michelle C. Dunn
;
Jason Duquette
;
Benjamin Fisher
;
Robert S. Foti
;
Kirk Henne
;
Xiao He
;
Yi-Ling Hu
;
Ron C. Kelly
;
Michael G.
John
son
;
Brian S. Lucas
;
John
McCarter
;
Lawrence R. McGee
;
Julio C. Medina
;
Daniela Metz
;
Tisha San Miguel
;
Deanna Mohn
;
Thuy Tran
;
Christine Vissinga
;
Sharon Wannberg
;
Douglas A. Whittington
;
John
Whoriskey
;
Gang Yu
;
Leeanne Zalameda
;
Xuxia Zhang
;
Timothy D. Cushing
刊名:Journal of Medicinal Chemistry
出版年:2016
2.
Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3Kδ Inhibitors
作者:
Youngsook Shin
;
Julia Suchomel
;
Mario Cardozo
;
Jason Duquette
;
Xiao He
;
Kirk Henne
;
Yi-Ling Hu
;
Ron C. Kelly
;
John
McCarter
;
Lawrence R. McGee
;
Julio C. Medina
;
Daniela Metz
;
Tisha San Miguel
;
Deanna Mohn
;
Thuy Tran
;
Christine Vissinga
;
Simon Wong
;
Sharon Wannberg
;
Douglas A. Whittington
;
John
Whoriskey
;
Gang Yu
;
Leeanne Zalameda
;
Xuxia Zhang
;
Timothy D. Cushing
刊名:Journal of Medicinal Chemistry
出版年:2016
3.
Facile Modulation of Antibody Fucosylation with Small Molecule Fucostatin Inhibitors and Cocrystal Structure with GDP-Mannose 4,6-Dehydratase
作者:
John
G. Allen
;
Mirna Mujacic
;
Michael J. Frohn
;
Alex J. Pickrell
;
Paul Kodama
;
Dhanashri Bagal
;
Tisha San Miguel
;
E. Allen Sickmier
;
Steve Osgood
;
Aleksander Swietlow
;
Vivian Li
;
John
B. Jordan
;
Ki-Won Kim
;
Anne-Marie C. Rousseau
;
Yong-Jae Kim
;
Seb Caille
;
Mike Achmatowicz
;
Oliver Thiel
;
Christopher H. Fotsch
;
Pranhitha Reddy
;
John
D.
McCarter
刊名:ACS Chemical Biology
出版年:2016
4.
Discovery and in Vivo Evaluation of (S)-N-(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and Related PI3K未 Inhibitors for Inflammation and Autoimmune
作者:
Timothy D. Cushing
;
Xiaolin Hao
;
Youngsook Shin
;
Kristin Andrews
;
Matthew Brown
;
Mario Cardozo
;
Yi Chen
;
Jason Duquette
;
Ben Fisher
;
Felix Gonzalez-Lopez de Turiso
;
Xiao He
;
Kirk R. Henne
;
Yi-Ling Hu
;
Randall Hungate
;
Michael G.
John
son
;
Ron C. Kelly
;
Brian Lucas
;
John
D.
McCarter
;
Lawrence R. McGee
;
Julio C. Medina
;
Tisha San Miguel
;
Deanna Mohn
;
Vatee Pattaropong
;
Liping H. Pettus
;
Andreas Reichelt
;
Robert M. Rzasa
;
Jennifer Seganish
;
Andrew S. Tasker
;
Robert C. Wahl
;
Sharon Wannberg
;
Douglas A. Whittington
;
John
Whoriskey
;
Gang Yu
;
Leeanne Zalameda
;
Dawei Zhang
;
Daniela P. Metz
刊名:Journal of Medicinal Chemistry
出版年:2015
5.
Systematic Study of the Glutathione (GSH) Reactivity of N-Arylacrylamides: 1. Effects of Aryl Substitution
作者:
Victor J. Cee
;
Laurie P. Volak
;
Yuping Chen
;
Michael D. Bartberger
;
Chris Tegley
;
Tara Arvedson
;
John
McCarter
;
Andrew S. Tasker
;
Christopher Fotsch
刊名:Journal of Medicinal Chemistry
出版年:2015
6.
Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511
作者:
Mark H. Norman
;
Kristin L. Andrews
;
Yunxin Y. Bo
;
Shon K. Booker
;
Sean Caenepeel
;
Victor J. Cee
;
Noel D. D鈥橝ngelo
;
Daniel J. Freeman
;
Bradley J. Herberich
;
Fang-Tsao Hong
;
Claire L. M. Jackson
;
Jian Jiang
;
Brian A. Lanman
;
Longbin Liu
;
John
D.
McCarter
;
Erin L. Mullady
;
Nobuko Nishimura
;
Liping H. Pettus
;
Anthony B. Reed
;
Tisha San Miguel
;
Adrian L. Smith
;
Markian M. Stec
;
Seifu Tadesse
;
Andrew Tasker
;
Divesh Aidasani
;
Xiaochun Zhu
;
Raju Subramanian
;
Nuria A. Tamayo
;
Ling Wang
;
Douglas A. Whittington
;
Bin Wu
;
Tian Wu
;
Ryan P. Wurz
;
Kevin Yang
;
Leeanne Zalameda
;
Nancy Zhang
;
Paul E. Hughes
刊名:Journal of Medicinal Chemistry
出版年:2012
7.
Structure-Based Design of a Novel Series of Potent, Selective Inhibitors of the Class I Phosphatidylinositol 3-Kinases
作者:
Adrian L. Smith
;
Noel D. D鈥橝ngelo
;
Yunxin Y. Bo
;
Shon K. Booker
;
Victor J. Cee
;
Brad Herberich
;
Fang-Tsao Hong
;
Claire L. M. Jackson
;
Brian A. Lanman
;
Longbin Liu
;
Nobuko Nishimura
;
Liping H. Pettus
;
Anthony B. Reed
;
Seifu Tadesse
;
Nuria A. Tamayo
;
Ryan P. Wurz
;
Kevin Yang
;
Kristin L. Andrews
;
Douglas A. Whittington
;
John
D.
McCarter
;
Tisha San Miguel
;
Leeanne Zalameda
;
Jian Jiang
;
Raju Subramanian
;
Erin L. Mullady
;
Sean Caenepeel
;
Daniel J. Freeman
;
Ling Wang
;
Nancy Zhang
;
Tian Wu
;
Paul E. Hughes
;
Mark H. Norman
刊名:Journal of Medicinal Chemistry
出版年:2012
8.
Correction to Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511
作者:
Mark H. Norman
;
Kristin L. Andrews
;
Yunxin Y. Bo
;
Shon K. Booker
;
Sean Caenepeel
;
Victor J. Cee
;
Noel D. D鈥橝ngelo
;
Daniel J. Freeman
;
Bradley J. Herberich
;
Fang-Tsao Hong
;
Claire L. M. Jackson
;
Jian Jiang
;
Brian A. Lanman
;
Longbin Liu
;
John
D.
McCarter
;
Erin L. Mullady
;
Nobuko Nishimura
;
Liping H. Pettus
;
Anthony B. Reed
;
Tisha San Miguel
;
Adrian L. Smith
;
Markian M. Stec
;
Seifu Tadesse
;
Andrew Tasker
;
Divesh Aidasani
;
Xiaochun Zhu
;
Raju Subramanian
;
Nuria A. Tamayo
;
Ling Wang
;
Douglas A. Whittington
;
Bin Wu
;
Tian Wu
;
Ryan P. Wurz
;
Kevin Yang
;
Leeanne Zalameda
;
Nancy Zhang
;
Paul E. Hughes
刊名:Journal of Medicinal Chemistry
出版年:2012
9.
Structural, Mechanistic, and Computational Analysis of the Effects of Anomeric Fluorines on Anomeric Fluoride Departure in 5-Fluoroxylosyl Fluorides
作者:
Seung Seo Lee
;
Ian R. Greig
;
David J. Vocadlo
;
John
D.
McCarter
;
Brian O. Patrick
;
Stephen G. Withers
刊名:Journal of the American Chemical Society
出版年:2011
10.
Structure鈥揂ctivity Relationships of Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors: Investigations of Various 6,5-Heterocycles to Improve Metabolic Stability
作者:
Markian M. Stec
;
Kristin L. Andrews
;
Shon K. Booker
;
Sean Caenepeel
;
Daniel J. Freeman
;
Jian Jiang
;
Hongyu Liao
;
John
McCarter
;
Erin L. Mullady
;
Tisha San Miguel
;
Raju Subramanian
;
Nuria Tamayo
;
Ling Wang
;
Kevin Yang
;
Leeanne P. Zalameda
;
Nancy Zhang
;
Paul E. Hughes
;
Mark H. Norman
刊名:Journal of Medicinal Chemistry
出版年:2011
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