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ACS电子期刊(60)
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NATURE电子期刊(81)
Elsevier电子期刊(806)
在“
ACS电子期刊
”中,
命中:
60
条,耗时:0.0210202 秒
在所有数据库中总计命中:
1,098
条
1.
Discovery of 6-Amino-2-{[(1S)-1-methylbutyl]oxy}-9-[5-(1-piperidinyl)pentyl]-7,9-dihydro-8H-purin-8-one (GSK2245035), a Highly Potent and Selective Intranasal Toll-Like Receptor 7 Agonist for the Treatment of Asthma
作者:
Keith Biggadike
;
Mahbub Ahmed
;
Doug I. Ball
;
Diane M. Coe
;
Deidre A. Dalmas Wilk
;
Chris D.
Edward
s
;
Bob H. Gibbon
;
Charlotte
J
. Hardy
;
Stephen A. Hermitage
;
J
oanne O. Hessey
;
Aimee E. Hillegas
;
Stephen C. Hughes
;
Linos Lazarides
;
Xiao Q. Lewell
;
Amanda Lucas
;
David N. Mallett
;
Mark A. Price
;
Fiona M. Priest
;
Diana
J
. Quint
;
Poonam Shah
;
Anesh Sitaram
;
Stephen A.
Smith
;
Richard Stocker
;
Naimisha A. Trivedi
;
Daphne C. Tsitoura
;
Victoria Weller
刊名:
J
ournal of Medicinal Chemistry
出版年:2016
2.
Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy
作者:
Kimberly O. Cameron
;
Daniel W. Kung
;
Amit S. Kalgutkar
;
Ravi G. Kurumbail
;
Russell Miller
;
Christopher T. Salatto
;
J
essica Ward
;
J
ane M. Withka
;
Samit K. Bhattacharya
;
Markus Boehm
;
Kris A. Borzilleri
;
J
anice A. Brown
;
Matthew Calabrese
;
Nicole L. Caspers
;
Emily Cokorinos
;
Edward
L. Conn
;
Matthew S. Dowling
;
David
J
. Edmonds
;
Heather Eng
;
Dilinie P. Fernando
;
Richard Frisbie
;
David Hepworth
;
J
ames Landro
;
Yuxia Mao
;
Francis Ra
j
amohan
;
Allan R. Reyes
;
Colin R. Rose
;
Tim Ryder
;
Andre Shavnya
;
Aaron C.
Smith
;
Meihua Tu
;
Angela C. Wolford
;
J
un Xiao
刊名:
J
ournal of Medicinal Chemistry
出版年:2016
3.
Molecular Dynamics Simulation Study of the Association of Lidocainium Docusate and Its Derivatives in Aqueous Solution
作者:
David
J
.
Smith
;
J
indal K. Shah
;
Edward
J
. Maginn
刊名:Molecular Pharmaceutics
出版年:2015
4.
Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3
作者:
Scott Boyd
;
J
oanna L. Brookfield
;
Susan E. Critchlow
;
Iain A. Cumming
;
Nicola
J
. Curtis
;
J
udit Debreczeni
;
S茅bastien L. Degorce
;
Craig Donald
;
Nicola
J
. Evans
;
Sam Groombridge
;
Philip Hopcroft
;
Neil P.
J
ones
;
J
ason G. Kettle
;
Scott Lamont
;
Hilary
J
. Lewis
;
Philip MacFaull
;
Sheila B. McLoughlin
;
Laurent
J
. M. Rigoreau
;
J
ames M.
Smith
;
Steve St-Gallay
;
J
ulie K. Stock
;
Andrew P. Turnbull
;
Edward
R. Wheatley
;
J
on Winter
;
J
onathan Wingfield
刊名:
J
ournal of Medicinal Chemistry
出版年:2015
5.
Glucose-Derived Palladium(0) Nanoparticles as in Situ-Formed Catalysts for Suzuki鈥揗iyaura Cross-Coupling Reactions in Isopropanol
作者:
J
ason E. Camp
;
J
ay J. Dunsford
;
Edward
P. Cannons
;
William
J
. Restorick
;
Anastasia Gadzhieva
;
Michael W. Fay
;
Robert
J
.
Smith
刊名:ACS Sustainable Chemistry & Engineering
出版年:2014
6.
Design of Potent and Selective Inhibitors to Overcome Clinical Anaplastic Lymphoma Kinase Mutations Resistant to Crizotinib
作者:
Qinhua Huang
;
Ted W.
J
ohnson
;
Simon Bailey
;
Alexei Brooun
;
Kevin D. Bunker
;
Ben
j
amin J. Burke
;
Michael R. Collins
;
Andrew S. Cook
;
J
. Jean Cui
;
Kevin N. Dack
;
J
udith G. Deal
;
Ya-Li Deng
;
Dac Dinh
;
Lars D. Engstrom
;
Mingying He
;
J
acqui Hoffman
;
Robert L. Hoffman
;
Patrick S.
J
ohnson
;
Robert S. Kania
;
Hieu Lam
;
J
ustine L. Lam
;
Phuong T. Le
;
Qiuhua Li
;
Laura Lingardo
;
Wei Liu
;
Melissa West Lu
;
Michele McTigue
;
Cynthia L. Palmer
;
Paul F. Richardson
;
Neal W. Sach
;
Hong Shen
;
Tod Smeal
;
Graham L.
Smith
;
Albert E. Stewart
;
Sergei Timofeevski
;
Konstantinos Tsaparikos
;
Hui Wang
;
Huichun Zhu
;
J
in
j
iang Zhu
;
Helen Y. Zou
;
Martin P.
Edward
s
刊名:
J
ournal of Medicinal Chemistry
出版年:2014
7.
Automated Structure Refinement for a Protein Heterodimer Complex Using Limited EPR Spectroscopic Data and a Rigid-Body Docking Algorithm: A Three-Dimensional Model for an Ankyrin-CDB3 Complex
作者:
Sarah
J
.
Edward
s
;
Christopher W. Moth
;
Sunghoon Kim
;
Suzanne Brandon
;
Zheng Zhou
;
Charles E. Cobb
;
Eric
J
. Hustedt
;
Albert H. Beth
;
J
arrod A.
Smith
;
Terry P. Lybrand
刊名:
J
ournal of Physical Chemistry B
出版年:2014
8.
Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-064639
作者:
Ted W.
J
ohnson
;
Paul F. Richardson
;
Simon Bailey
;
Alexei Brooun
;
Ben
j
amin J. Burke
;
Michael R. Collins
;
J
. Jean Cui
;
J
udith G. Deal
;
Ya-Li Deng
;
Dac Dinh
;
Lars D. Engstrom
;
Mingying He
;
J
acqui Hoffman
;
Robert L. Hoffman
;
Qinhua Huang
;
Robert S. Kania
;
J
ohn C. Kath
;
Hieu Lam
;
J
ustine L. Lam
;
Phuong T. Le
;
Laura Lingardo
;
Wei Liu
;
Michele McTigue
;
Cynthia L. Palmer
;
Neal W. Sach
;
Tod Smeal
;
Graham L.
Smith
;
Albert E. Stewart
;
Sergei Timofeevski
;
Huichun Zhu
;
J
in
j
iang Zhu
;
Helen Y. Zou
;
Martin P.
Edward
s
刊名:
J
ournal of Medicinal Chemistry
出版年:2014
9.
Structure-Based Design of Potent and Selective Leishmania N-Myristoyltransferase Inhibitors
作者:
J
ennie A. Hutton
;
Victor Goncalves
;
J
ames A. Brannigan
;
Daniel Paape
;
Megan H. Wright
;
Thomas M. Waugh
;
Shirley M. Roberts
;
Andrew S. Bell
;
Anthony
J
. Wilkinson
;
Deborah F.
Smith
;
Robin
J
. Leatherbarrow
;
Edward
W. Tate
刊名:
J
ournal of Medicinal Chemistry
出版年:2014
10.
Passive Lipoidal Diffusion and Carrier-Mediated Cell Uptake Are Both Important Mechanisms of Membrane Permeation in Drug Disposition
作者:
Dennis
Smith
;
Per Artursson
;
Alex Avdeef
;
Li Di
;
Gerhard F. Ecker
;
Bernard Faller
;
J
. Brian Houston
;
Manfred Kansy
;
Edward
H. Kerns
;
Stefanie D. Kr盲mer
;
Hans Lennern盲s
;
Han van de Waterbeemd
;
Kiyohiko Sugano
;
Bernard Testa
刊名:Molecular Pharmaceutics
出版年:2014
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