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Wiley电子期刊(7)
SpringerLink电子期刊(17)
ACS电子期刊(35)
Springer电子图书(2)
Elsevier电子期刊(49)
在“
ACS电子期刊
”中,
命中:
35
条,耗时:小于0.01 秒
在所有数据库中总计命中:
110
条
1.
Elucidating the Origin of Long Residence Time Binding for Inhibitors of the Metalloprotease Thermolysin
作者:
Jonathan Cramer
;
Stefan G. Krimmer
;
Veronica Fridh
;
Tobias Wulsdorf
;
Robert Karlsson
;
Andreas Heine
;
Gerhard
Klebe
刊名:ACS Chemical Biology
出版年:2017
2.
Six Biophysical Screening Methods Miss a Large Proportion of Crystallographically Discovered Fragment Hits: A Case Study
作者:
Johannes Schiebel
;
Nedyalka Radeva
;
Stefan G. Krimmer
;
Xiaojie Wang
;
Martin Stieler
;
Frederik R. Ehrmann
;
Kan Fu
;
Alexander Metz
;
Franziska U. Huschmann
;
Manfred S. Weiss
;
Uwe Mueller
;
Andreas Heine
;
Gerhard
Klebe
刊名:ACS Chemical Biology
出版年:2016
3.
New Insights into Human 17β-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor
作者:
Nicole Bertoletti
;
Florian Braun
;
Mahalia Lepage
;
Gabriele Möller
;
Jerzy Adamski
;
Andreas Heine
;
Gerhard
Klebe
;
Sandrine Marchais-Oberwinkler
刊名:Journal of Medicinal Chemistry
出版年:2016
4.
Optimization of Cyclic Plasmin Inhibitors: From Benzamidines to Benzylamines
作者:
Stefan Hinkes
;
André Wuttke
;
Sebastian M. Saupe
;
Teodora Ivanova
;
Sebastian Wagner
;
Anna Knörlein
;
Andreas Heine
;
Gerhard
Klebe
;
Torsten Steinmetzer
刊名:Journal of Medicinal Chemistry
出版年:2016
5.
Kinetic and Structural Insights into the Mechanism of Binding of Sulfonamides to Human Carbonic Anhydrase by Computational and Experimental Studies
作者:
Roberto Gaspari
;
Chris Rechlin
;
Andreas Heine
;
Giovanni Bottegoni
;
Walter Rocchia
;
Daniel Schwarz
;
Jörg Bomke
;
Hans-Dieter Gerber
;
Gerhard
Klebe
;
Andrea Cavalli
刊名:Journal of Medicinal Chemistry
出版年:2016
6.
Experimental Active-Site Mapping by Fragments: Hot Spots Remote from the Catalytic Center of Endothiapepsin
作者:
Nedyalka Radeva
;
Stefan G. Krimmer
;
Martin Stieler
;
Kan Fu
;
Xiaojie Wang
;
Frederik R. Ehrmann
;
Alexander Metz
;
Franziska U. Huschmann
;
Manfred S. Weiss
;
Uwe Mueller
;
Johannes Schiebel
;
Andreas Heine
;
Gerhard
Klebe
刊名:Journal of Medicinal Chemistry
出版年:2016
7.
First Structure–Activity Relationship of 17β-Hydroxysteroid Dehydrogenase Type 14 Nonsteroidal Inhibitors and Crystal Structures in Complex with the Enzyme
作者:
Florian Braun
;
Nicole Bertoletti
;
Gabriele Möller
;
Jerzy Adamski
;
Torsten Steinmetzer
;
Mohamed Salah
;
Ahmed S. Abdelsamie
;
Chris J. van Koppen
;
Andreas Heine
;
Gerhard
Klebe
;
Sandrine Marchais-Oberwinkler
刊名:Journal of Medicinal Chemistry
出版年:2016
8.
Rational Design of Thermodynamic and Kinetic Binding Profiles by Optimizing Surface Water Networks Coating Protein-Bound Ligands
作者:
Stefan G. Krimmer
;
Jonathan Cramer
;
Michael Betz
;
Veronica Fridh
;
Robert Karlsson
;
Andreas Heine
;
Gerhard
Klebe
刊名:Journal of Medicinal Chemistry
出版年:2016
9.
Impact of Surface Water Layers on Protein–Ligand Binding: How Well Are Experimental Data Reproduced by Molecular Dynamics Simulations in a Thermolysin Test Case?
作者:
Michael Betz
;
Tobias Wulsdorf
;
Stefan G. Krimmer
;
Gerhard
Klebe
刊名:Journal of Chemical Information and Modeling
出版年:2016
10.
Active Site Mapping of an Aspartic Protease by Multiple Fragment Crystal Structures: Versatile Warheads To Address a Catalytic Dyad
作者:
Nedyalka Radeva
;
Johannes Schiebel
;
Xiaojie Wang
;
Stefan G. Krimmer
;
Kan Fu
;
Martin Stieler
;
Frederik R. Ehrmann
;
Alexander Metz
;
Thomas Rickmeyer
;
Michael Betz
;
Johan Winquist
;
Ah Young Park
;
Franziska U. Huschmann
;
Manfred S. Weiss
;
Uwe Mueller
;
Andreas Heine
;
Gerhard
Klebe
刊名:Journal of Medicinal Chemistry
出版年:2016
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