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Springer电子图书(2)
NATURE电子期刊(1)
ACS电子期刊(10)
SpringerLink电子期刊(2)
Elsevier电子期刊(8)
在“
ACS电子期刊
”中,
命中:
10
条,耗时:小于0.01 秒
在所有数据库中总计命中:
23
条
1.
The Rational Design of Selective Benzoxazepin Inhibitors of the α-Isoform of Phosphoinositide 3-Kinase Culminating in the Identification of (S)-2-((2-(1-Isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydroben
作者:
Timothy P. Heffron
;
Robert A. Heald
;
Chudi Ndubaku
;
BinQing Wei
;
Martin Augistin
;
Steven Do
;
Kyle Edgar
;
Charles Eigenbrot
;
Lori Friedman
;
Emanuela Gancia
;
Philip S. Jackson
;
Graham Jones
;
Aleksander Kolesnikov
;
Leslie B. Lee
;
John D. Lesnick
;
Cristina Lewis
;
Neville McLean
;
Mario M?rtl
;
Jim Nonomiya
;
Jodie Pang
;
Steve Price
;
Wei Wei Prior
;
Laurent Salphati
;
Steve Sideris
;
Steven T. Staben
;
Stefan Steinbacher
;
Vickie Tsui
;
Jeffrey Wallin
;
Deepak
Sampath
;
Alan G. Olivero
刊名:Journal of Medicinal Chemistry
出版年:2016
2.
Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors
作者:
Mark Zak
;
Po-wai Yuen
;
Xiongcai Liu
;
Snahel Patel
;
Deepak
Sampath
;
Jason Oeh
;
Bianca M. Liederer
;
Weiru Wang
;
Thomas O’Brien
;
Yang Xiao
;
Nicholas Skelton
;
Rongbao Hua
;
Jasleen Sodhi
;
Yunli Wang
;
Lei Zhang
;
Guiling Zhao
;
Xiaozhang Zheng
;
Yen-Ching Ho
;
Kenneth W. Bair
;
Peter S. Dragovich
刊名:Journal of Medicinal Chemistry
出版年:2016
3.
An Anti-B7-H4 Antibody鈥揇rug Conjugate for the Treatment of Breast Cancer
作者:
Steven R. Leong
;
Wei-Ching Liang
;
Yan Wu
;
Lisa Crocker
;
Eric Cheng
;
Deepak
Sampath
;
Rachana Ohri
;
Helga Raab
;
Philip E. Hass
;
Thinh Pham
;
Ron Firestein
;
Dongwei Li
;
Melissa Schutten
;
Nicola J. Stagg
;
Annie Ogasawara
;
Neelima Koppada
;
Leslie Roth
;
Simon P. Williams
;
Byoung-Chul Lee
;
Cecile Chalouni
;
Ivan Peng
;
Jason DeVoss
;
Jarrod Tremayne
;
Paul Polakis
;
Andrew G. Polson
刊名:Molecular Pharmaceutics
出版年:2015
4.
Fragment-Based Identification of Amides Derived from trans-2-(Pyridin-3-yl)cyclopropanecarboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT)
作者:
Anthony M. Giannetti
;
Xiaozhang Zheng
;
Nicholas J. Skelton
;
Weiru Wang
;
Brandon J. Bravo
;
Kenneth W. Bair
;
Timm Baumeister
;
Eric Cheng
;
Lisa Crocker
;
Yezhen Feng
;
Janet Gunzner-Toste
;
Yen-Ching Ho
;
Rongbao Hua
;
Bianca M. Liederer
;
Yongbo Liu
;
Xiaolei Ma
;
Thomas O’Brien
;
Jason Oeh
;
Deepak
Sampath
;
Youming Shen
;
Chengcheng Wang
;
Leslie Wang
;
Hongxing Wu
;
Yang Xiao
;
Po-wai Yuen
;
Mark Zak
;
Guiling Zhao
;
Qiang Zhao
;
Peter S. Dragovich
刊名:Journal of Medicinal Chemistry
出版年:2014
5.
Discovery of 2-{3-[2-(1-Isopropyl-3-methyl-1H-1,2鈥?-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl]-1H-pyrazol-1-yl}-2-methylpropanamide (GDC-0032): A 尾-Sparing
作者:
Chudi O. Ndubaku
;
Timothy P. Heffron
;
Steven T. Staben
;
Matthew Baumgardner
;
Nicole Blaquiere
;
Erin Bradley
;
Richard Bull
;
Steven Do
;
Jennafer Dotson
;
Danette Dudley
;
Kyle A. Edgar
;
Lori S. Friedman
;
Richard Goldsmith
;
Robert A. Heald
;
Aleksandr Kolesnikov
;
Leslie Lee
;
Cristina Lewis
;
Michelle Nannini
;
Jim Nonomiya
;
Jodie Pang
;
Steve Price
;
Wei Wei Prior
;
Laurent Salphati
;
Steve Sideris
;
Jeffery J. Wallin
;
Lan Wang
;
BinQing Wei
;
Deepak
Sampath
;
Alan G. Olivero
刊名:Journal of Medicinal Chemistry
出版年:2013
6.
Discovery of Potent and Selective Pyrazolopyrimidine Janus Kinase 2 Inhibitors
作者:
Emily J. Hanan
;
Anne van Abbema
;
Kathy Barrett
;
Wade S. Blair
;
Jeff Blaney
;
Christine Chang
;
Charles Eigenbrot
;
Sean Flynn
;
Paul Gibbons
;
Christopher A. Hurley
;
Jane R. Kenny
;
Janusz Kulagowski
;
Leslie Lee
;
Steven R. Magnuson
;
Claire Morris
;
Jeremy Murray
;
Richard M. Pastor
;
Tom Rawson
;
Michael Siu
;
Mark Ultsch
;
Aihe Zhou
;
Deepak
Sampath
;
Joseph P. Lyssikatos
刊名:Journal of Medicinal Chemistry
出版年:2012
7.
Potent, Selective, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin Kinase Domain Exhibiting Single Agent Antiproliferative Activity
作者:
Michael F. T. Koehler
;
Philippe Bergeron
;
Elizabeth Blackwood
;
Krista K. Bowman
;
Yung-Hsiang Chen
;
Gauri Deshmukh
;
Xiao Ding
;
Jennifer Epler
;
Kevin Lau
;
Leslie Lee
;
Lichuan Liu
;
Cuong Ly
;
Shiva Malek
;
Jim Nonomiya
;
Jason Oeh
;
Daniel F. Ortwine
;
Deepak
Sampath
;
Steve Sideris
;
Lan Trinh
;
Tom Truong
;
Jiansheng Wu
;
Zhonghua Pei
;
Joseph P. Lyssikatos
刊名:Journal of Medicinal Chemistry
出版年:2012
8.
Discovery and Preclinical Pharmacology of a Selective ATP-Competitive Akt Inhibitor (GDC-0068) for the Treatment of Human Tumors
作者:
James F. Blake
;
Rui Xu
;
Josef R. Bencsik
;
Dengming Xiao
;
Nicholas C. Kallan
;
Stephen Schlachter
;
Ian S. Mitchell
;
Keith L. Spencer
;
Anna L. Banka
;
Eli M. Wallace
;
Susan L. Gloor
;
Matthew Martinson
;
Richard D. Woessner
;
Guy P.A. Vigers
;
Barbara J. Brandhuber
;
Jun Liang
;
Brian S. Safina
;
Jun Li
;
Birong Zhang
;
Christine Chabot
;
Steven Do
;
Leslie Lee
;
Jason Oeh
;
Deepak
Sampath
;
Brian B. Lee
;
Kui Lin
;
Bianca M. Liederer
;
Nicholas J. Skelton
刊名:Journal of Medicinal Chemistry
出版年:2012
9.
Discovery of a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor (GDC-0980) for the Treatment of Cancer
作者:
Daniel P. Sutherlin
;
Linda Bao
;
Megan Berry
;
Georgette Castanedo
;
Irina Chuckowree
;
Jenna Dotson
;
Adrian Folks
;
Lori Friedman
;
Richard Goldsmith
;
Janet Gunzner
;
Timothy Heffron
;
John Lesnick
;
Cristina Lewis
;
Simon Mathieu
;
Jeremy Murray
;
Jim Nonomiya
;
Jodie Pang
;
Niel Pegg
;
Wei Wei Prior
;
Lionel Rouge
;
Laurent Salphati
;
Deepak
Sampath
;
Qingping Tian
;
Vickie Tsui
;
Nan Chi Wan
;
Shumei Wang
;
BinQing Wei
;
Christian Wiesmann
;
Ping Wu
;
Bing-Yan Zhu
;
Alan Olivero
刊名:Journal of Medicinal Chemistry
出版年:2011
10.
Discovery of (Thienopyrimidin-2-yl)aminopyrimidines as Potent, Selective, and Orally Available Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors for the Treatment of Cancer
作者:
Daniel P. Sutherlin
;
Deepak
Sampath
;
Megan Berry
;
Georgette Castanedo
;
Zhigang Chang
;
Irina Chuckowree
;
Jenna Dotson
;
Adrian Folkes
;
Lori Friedman
;
Richard Goldsmith
;
Tim Heffron
;
Leslie Lee
;
John Les
刊名:Journal of Medicinal Chemistry
出版年:2010
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