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SpringerLink电子期刊(2)
Elsevier电子期刊(3)
ACS电子期刊(4)
在“
Elsevier电子期刊
”中,
命中:
3
条,耗时:0.0289933 秒
在所有数据库中总计命中:
9
条
1.
Structure-activity relationships of 4-hydroxy-4-biaryl-proline acylsulfonamide tripeptides: A series of potent NS3 protease inhibitors for the treatment of hepatitis C virus
作者:
Alan
Xiangdong
Wang
a
;
alan
.
wang
@bms.com
;
Jie Chen
a
;
Qian Zhao
a
;
Li-Qiang Sun
a
;
Jacques Friborg
b
;
Fei Yu
b
;
Dennis Hernandez
b
;
Andrew C. Good
c
;
Herbert E. Klei
c
;
Ramkumar Rajamani
c
;
Kathy Mosure
d
;
Jay O. Knipe
d
;
Danshi Li
d
;
Jialong Zhu
d
;
Paul C. Levesque
d
;
Fiona McPhee
b
;
Nicholas A. Meanwell
a
;
Paul M. Scola
a
;
关键词:
HCV NS3/4A serine protease inhibitors
;
Tripeptide acylsulfonamides
;
C4 aryl
;
C4 hydroxy-proline
;
Potent and orally bioavailable
;
Cardiovascular profiles
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
2.
Respiratory syncytial virus fusion inhibitors. Part 5: Optimization of benzimidazole substitution patterns towards derivatives with improved activity
作者:
Xiangdong
Alan
Wang
;
Christopher W. Cianci
;
Kuo-Long Yu
;
Keith D. Combrink
;
Jan W. Thuring
;
Yi Zhang
;
Rita L. Civiello
;
Kathleen F. Kadow
;
Julia Roach
;
Zhufang Li
;
David R. Langley
;
Mark Krystal
;
Nic
关键词:
RSV fusion inhibitor
;
Substitution of the benzimidazole
;
Binding pocket
;
5-Aminomethyl analogue
;
Retained activity
;
Resistant virus
;
Asp200
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2007
3.
Respiratory syncytial virus fusion inhibitors. Part 3: Water-soluble benzimidazol-2-one derivatives with antiviral activity in vivo
作者:
Kuo-Long Yu
;
Xiangdong
Alan
Wang
;
Rita L. Civiello
;
Ashok K. Trehan
;
Bradley C. Pearce
;
Zhiwei Yin
;
Keith D. Combrink
;
H. Belgin Gulgeze
;
Yi Zhang
;
Kathleen F. Kadow
et al.
关键词:
Water-soluble respiratory syncytial virus inhibitors
;
Antiviral
;
Benzimidazol-2-one derivatives
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2006
1
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