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SpringerLink电子期刊(1)
Elsevier电子期刊(10)
ACS电子期刊(5)
在“
Elsevier电子期刊
”中,
命中:
10
条,耗时:0.0129931 秒
在所有数据库中总计命中:
16
条
1.
Discovery and optimization of a series of liver X receptor antagonists
作者:
XianYun Jiao
;
David J. Kopecky
;
Ben Fisher
;
Derek
E.
Piper
;
Marc Labelle
;
Sharon McKendry
;
Martin Harrison
;
Stuart Jones
;
Juan Jaen
;
Andrew K. Shiau
;
Patrick Escaron
;
Jean Danao
;
Anne Chai
;
Peter Coward
;
Frank Kayser
关键词:
LXR ¦Á/¦Â
;
Antagonist
;
GAL4 reporter gene assay
;
mSREBP-1c reporter
;
Conversion
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2012
2.
Molecular basis of PCSK9 function
作者:
Gilles Lambert
;
Francesca Charlton
;
Kerry-Anne Rye
;
Derek
E.
Piper
关键词:
Hypercholesterolemia
;
LDL receptor
;
PCSK9
;
Therapeutic target
刊名:Atherosclerosis
出版年:2009
3.
The Crystal Structure of PCSK9: A Regulator of Plasma LDL-Cholesterol
作者:
Derek
E.
Piper
;
Simon Jackson
;
Qiang Liu
;
William G. Romanow
;
Susan Shetterly
;
Stephen T. Thibault
;
Bei Shan
;
Nigel P.C. Walker
关键词:
SIGNALING
;
HUMDISEASE
刊名:Structure
出版年:2007
4.
SB-399885 is a potent, selective 5-HT
6
receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models
作者:
Warren D. Hirst
;
Tania O. Stean
;
Derek
C. Rogers
;
David Sunter
;
Pippa Pugh
;
Stephen F. Moss
;
Steven M. Bromidge
;
Graham Riley
;
Douglas R. Smith
;
Sarah Bartlett
;
et al.
关键词:
5-HT
;
Memory
;
Cognition
;
Water maze
;
Acetylcholine
;
In vivo
microdialysis
刊名:European Journal of Pharmacology
出版年:2006
5.
Conformationally constrained N
1
-arylsulfonyltryptamine derivatives as 5-HT
6
receptor antagonists
作者:
Derek
C. Cole
;
William J. Lennox
;
Joseph R. Stock
;
John W. Ellingboe
;
Hossein Mazandarani
;
Deborah L. Smith
;
Guoming Zhang
;
Gregory J. Tawa and Lee E. Schechter
关键词:
N
1
-Arylsulfonyltryptamine
;
5-HT6
;
Serotonin
;
Receptor
;
Antagonist
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2005
6.
Novel Inhibitors of Hepatitis C Virus RNA-dependent RNA Polymerases
作者:
Gary Lee
;
Derek
E.
Piper
;
Zhulun Wang
;
John Anzola
;
Jay Powers
;
Nigel Walker and Yang Li
刊名:Journal of Molecular Biology
出版年:2006
7.
Infections and severe sepsis in solid-organ transplant patients admitted from a university-based ED
作者:
Stephen Trzeciak
;
R
;
all Sharer
;
Derek
Piper
;
Therese Chan
;
Chad Kessler
;
R. Phillip Dellinger
;
Kenneth J. Pursell
关键词:
Emergency service
;
hospital
;
emergency medicine
;
infection
;
infectious diseases
;
transplantation
;
sepsis
;
severe sepsis
刊名:The American Journal of Emergency Medicine
出版年:2004
8.
Design, synthesis, computational and biological evaluation of new anxiolytics
作者:
Geronikaki
;
Athina
;
Babaev
;
Eugeni
;
Dearden
;
John
;
Dehaen
;
Wim
;
Filimonov
;
Dmitrii
;
Galaeva
;
Irina
;
et. al.
关键词:
Anxiolytics
;
Synthesis
;
Thiazoles
;
Pyrazoles
;
2-Indolinones
;
Fused imidazoles
;
pass
刊名:Bioorganic and Medicinal Chemistry
出版年:2004
9.
Pharmacological profile of SB-357134: A potent, selective, brain penetrant, and orally active 5-HT
6
receptor antagonist
作者:
Stean
;
Tania O.
;
Hirst
;
Warren D.
;
Thomas
;
David R.
;
Price
;
Gary W.
;
Rogers
;
Derek
;
Riley
;
Graham
;
et. al.
关键词:
SB-357134
;
5-HT
6
receptor
;
[
125
I]SB-258585
;
[
3
H]LSD
;
cAMP
;
Maximal electroshock seizure threshold (MEST) test
;
Morris water maze
;
Memory
;
Learning
刊名:Pharmacology Biochemistry and Behavior
出版年:2002
10.
Structure of a HoxB1–Pbx1 Heterodimer Bound to DNA: Role of the Hexapeptide and a Fourth Homeodomain Helix in Complex Formation
作者:
Derek
E.
Piper
;
Adrian H. Batchelor
;
Ching-Pin Chang
;
Michael L. Cleary
;
Cynthia Wolberger
刊名:Cell
出版年:1999
1
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