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SpringerLink电子期刊(2)
Elsevier电子期刊(17)
ACS电子期刊(30)
在“
Elsevier电子期刊
”中,
命中:
17
条,耗时:小于0.01 秒
在所有数据库中总计命中:
49
条
1.
Substituted pyrrolo[2,3-d]pyrimidines as Cryptosporidium hominis thymidylate synthase inhibitors
作者:
Vidya P. Kumar
;
Kathleen M. Frey
;
Yiqiang Wang
;
Hitesh K. Jain
;
Aleem
Gangjee
;
Karen S. Anderson
关键词:
Pyrrolo[2
;
3-d]pyrimidines
;
Thymidylate synthase
;
Dihydrofolate reductase
;
Cryptosporidium hominis
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
2.
Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agents
作者:
Aleem
Gangjee
;
Ying Zhao
;
Michael A. Ihnat
;
Jessica E. Thorpe
;
Lora C. Bailey-Downs
;
Roy L. Kisliuk
关键词:
RTK
;
receptor tyrosine kinase
;
PDGFR¦Â
;
platelet-derived growth factor receptor ¦Â
;
FGFR
;
fibroblast growth factor receptor
;
VEGFR
;
vascular epidermal growth factor receptor
;
IGFR
;
insulin growth factor receptor
;
EGFR
;
epidermal growth factor receptor
;
CA
刊名:Bioorganic and Medicinal Chemistry
出版年:2012
3.
2-Amino-4-methyl-5-phenylethyl substituted-7-N-benzyl-pyrrolo[2,3-d]pyrimidines as novel antitumor antimitotic agents that also reverse tumor resistance
作者:
Aleem
Gangjee
a
;
gangjee
@duq.edu"" rel=""nofollow
;
Ojas A. Namjoshi
a
;
Staci N. Keller
b
;
Charles D. Smith
b
关键词:
Antimitotic
;
Tumor resistance reversal
;
Cytotoxic
;
Sonogashira coupling
刊名:Bioorganic and Medicinal Chemistry
出版年:2011
4.
Design, synthesis and evaluation of 2-amino-4-m-bromoanilino-6-arylmethyl-7H-pyrrolo[2,3-d]pyrimidines as tyrosine kinase inhibitors and antiangiogenic agents
作者:
Aleem
Gangjee
;
Ying Zhao
;
Sudhir Raghavan
;
Michael A. Ihnat
;
Bryan C. Disch
关键词:
Multiple receptor
;
Tyrosine kinase inhibitors
;
Antiangiogenic agents
刊名:Bioorganic and Medicinal Chemistry
出版年:2010
5.
The contribution of a 2-amino group on receptor tyrosine kinase inhibition and antiangiogenic activity in 4-anilinosubstituted pyrrolo[2,3-d]pyrimidines
作者:
Aleem
Gangjee
;
Ojas A. Namjoshi
;
Michael A. Ihnat
;
Aaron Buchanan
关键词:
Tyrosine kinase inhibitors
;
Antitumor agents
;
Structure–
;
activity relationship
;
Molecular modeling
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
6.
Synthesis and biological activity of N
4
-phenylsubstituted-6-(2,4-dichloro phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic and antitumor agents
作者:
Aleem
Gangjee
;
Sonali Kurup
;
Michael A Ihnat
;
Jessica E. Thorpe
;
Satyendra S. Shenoy
关键词:
Pyrrolo[2
;
3-
d
]pyrimidines
;
Receptor tyrosine kinase inhibitors
;
Antiangiogenic agents
;
Antitumor agents
刊名:Bioorganic and Medicinal Chemistry
出版年:2010
7.
CoMFA analysis of tgDHFR and rlDHFR based on antifolates with 6–5 fused ring system using the all-orientation search (AOS) routine and a modified cross-validated r
2
-guided region selection (q
2
-GRS) routine and its initial appl
作者:
Aleem
Gangjee
;
Xin Lin
;
Lisa R. Biondo
;
Sherry F. Queener
关键词:
Antifolates
;
Dihydrofolate reductase
;
CoMFA analysis
;
Selective inhibitors
刊名:Bioorganic and Medicinal Chemistry
出版年:2010
8.
2,4-Diamino-5-methyl-6-substituted arylthio-furo[2,3-d]pyrimidines as novel classical and nonclassical antifolates as potential dual thymidylate synthase and dihydrofolate reductase inhibitors
作者:
Aleem
Gangjee
;
Hiteshkumar D. Jain
;
Jaclyn Phan
;
Xin Guo
;
Sherry F. Queener
;
Roy L. Kisliuk
关键词:
Furo[2
;
3-
d
]pyrimidines
;
Thymidylate synthase
;
Dihydrofolate reductase
;
Dual inhibitors
刊名:Bioorganic and Medicinal Chemistry
出版年:2010
9.
Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d
作者:
Aleem
Gangjee
;
Wei Li
;
Lu Lin
;
Yibin Zeng
;
Michael Ihnat
;
Linda A. Warnke
;
Dixy W. Green
;
Vivian Cody
;
Jim Pace
;
Sherry F. Queener
关键词:
PDGFR-β
;
EGFR
;
Dihydrofolate reductase
;
Multitargeted inhibitors
刊名:Bioorganic and Medicinal Chemistry
出版年:2009
10.
Design, synthesis and biological evaluation of substituted pyrrolo[2,3-d]pyrimidines as multiple receptor tyrosine kinase inhibitors and antiangiogenic agents
作者:
Aleem
Gangjee
;
Ojas A. Namjoshi
;
Jianming Yu
;
Michael A. Ihnat
;
Jessica E. Thorpe
;
Linda A. Warnke
关键词:
Multiple receptor
;
Tyrosine kinase inhibitors
;
Antiangiogenic agents
刊名:Bioorganic and Medicinal Chemistry
出版年:2008
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