设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
Wiley电子期刊(1)
NATURE电子期刊(4)
ACS电子期刊(29)
SpringerLink电子期刊(26)
Elsevier电子期刊(30)
在“
Elsevier电子期刊
”中,
命中:
30
条,耗时:小于0.01 秒
在所有数据库中总计命中:
90
条
1.
Rational Design of Selective Allosteric Inhibitors of PHGDH and Serine Synthesis with Anti-tumor Activity
作者:
Qian Wang
1
;
6
;
Maria V. Liberti
2
;
3
;
6
;
Pei Liu
1
;
Xiaobing Deng
4
;
Ying Liu
1
;
5
;
Jason W. Locasale
2
;
jason.locasale@duke.edu
;
Luhua
Lai
1
;
4
;
5
;
7
;
lh
lai
@pku.edu.cn
关键词:
cancer cell metabolism
;
PHGDH
;
de novo serine synthesis
;
allosteric inhibitor
;
rational design
;
virtual screen
;
anti-tumor
;
in vivo
刊名:Cell Chemical Biology
出版年:2017
2.
Development of 3,5-dinitrobenzoate-based 5-lipoxygenase inhibitors
作者:
Erchang Shang
;
Ying Liu
;
liuying@pku.edu.cn" class="auth_mail
;
Yiran Wu
;
Wei Zhu
;
Chong He
;
Luhua
Lai
关键词:
OFHSAGBLERSCES-UHFFFAOYSA-N
;
IBGIDLMEYRZWOK-UHFFFAOYSA-N
;
OYXLKHVOIHISEL-UHFFFAOYSA-N
;
AJGDGCHSUWBVKE-UHFFFAOYSA-N
;
LVNXQZZIIQICEQ-UHFFFAOYSA-N
;
SEJIIGNMAIGSHF-UHFFFAOYSA-N
;
WWIVUCGLXUETFF-UHFFFAOYSA-N
;
MIOZEVVUBICFAX-UHFFFAOYSA-N
;
ZLBSCQKWICLCTP-UHFFFAOYSA-N
;
WSDHQVWNYXYMCJ-UHFFFAOYSA-N
;
UZSXNOWPVBPHDR-UHFFFAOYSA-N
;
JNIVGHFBGSNDHF-UHFFFAOYSA-N
;
HXNJCSPTZLUSKA-UHFFFAOYSA-N
;
HCOVQZMTFULNHV-UHFFFAOYSA-N
;
XETLONOKCAMDQB-UHFFFAOYSA-N
;
WFKUTCSJWDWLLR-UHFFFAOYSA-N
;
GSTHFOGWYKTHSB-UHFFFAOYSA-N
;
NOGRHFA
刊名:Bioorganic and Medicinal Chemistry
出版年:15 April, 2014
3.
Optimization of 5-hydroxytryptamines as dual function inhibitors targeting phospholipase A
2
and leukotriene A
4
hydrolase
作者:
Hu Meng
;
Ying Liu
;
liuying@pku.edu.cn
;
Yujing Zhai
;
Luhua
Lai
关键词:
5-Hydroxytryptamine
;
Optimization
;
PLA2
;
LTA4H
;
Dual function inhibitor
刊名:European Journal of Medicinal Chemistry
出版年:2013
4.
Antibacterial properties of recombinant human non-pancreatic secretory phospholipase A
2
作者:
Shunchen Qiu
;
Luhua
Lai
关键词:
PLA2
;
phospholipase A2
;
sPLA2
;
secretory phospholipase A2
;
hnpsPLA2
;
human non-pancreatic secretory phospholipase A2
刊名:Biochemical and Biophysical Research Communications
出版年:15 November, 2013
5.
Slow and Bimolecular Folding of a De Novo Designed Monomeric Protein DS119
作者:
Cheng Zhu
;
Ziwei Dai
;
Huanhuan Liang
;
Tao Zhang
;
Feng Gai
;
Luhua
Lai
刊名:Biophysical Journal
出版年:5 November, 2013
6.
Folding Simulations of a De Novo Designed Protein with a βαβ Fold
作者:
Yifei Qi
;
Yongqi Huang
;
Huanhuan Liang
;
Zhirong Liu
;
Luhua
Lai
刊名:Biophysical Journal
出版年:2010
7.
Resurveying the Tris buffer solution: The specific interaction between tris(hydroxymethyl)aminomethane and lysozyme
作者:
Li Quan
;
Dengguo Wei
;
Xiaolu Jiang
;
Yang Liu
;
Zhiyu Li
;
Na Li
;
Kean Li
;
Feng Liu
;
Luhua
Lai
关键词:
Lysozyme
;
Tris(hydroxymethyl)aminomethane
;
Protein–
;
buffer binding
;
Quartz crystal microbalance biosensor
;
Surface plasmon resonance
;
Molecular docking
刊名:Analytical Biochemistry
出版年:2008
8.
Activation and inhibition of leukotriene A
4
hydrolase aminopeptidase activity by diphenyl ether and derivatives
作者:
Xiaolu Jiang
;
Lu Zhou
;
Dengguo Wei
;
Hu Meng
;
Ying Liu
;
Luhua
Lai
关键词:
Leukotriene A
4
hydrolase/aminopeptidase
;
Diphenyl ether derivatives
;
Activators
;
Inhibitors
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2008
9.
Preheating induced homogeneity of the small heat shock protein from Methanococcus jannaschii
作者:
Aoneng Cao
;
Zheng Wang
;
Ping Wei
;
Fei Xu
;
Jie Cao
;
Luhua
Lai
关键词:
Heat shock protein
;
Chaperone
;
Protein folding
;
Homogeneity
;
HSP 16.5
刊名:Biochimica et Biophysica Acta - Proteins and Proteomics
出版年:2008
10.
Hierarchical Unfolding of Mj HSP16.5
作者:
Zheng Wang
;
Bing
Lai
;
Jie Cao
;
Zhu Li
;
Lili Qu
;
Aoneng Cao
;
Luhua
Lai
关键词:
Small heat shock protein
;
Mj HSP16.5
;
Protein folding
;
Denaturant
;
Hierarchical unfolding
;
Circular dichroism
刊名:Acta Physico-Chimica Sinica
出版年:2008
1
2
3
按检索点细分(30)
作者(30)
按出版年细分(30)
2027年及以后(1)
2017年(1)
2013年(1)
2010年(1)
2008年(4)
2007年(3)
2006年(2)
2005年(3)
2004年(1)
2003年(1)
2002年(2)
2001年(2)
2000年(3)
2000年及以前(5)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.