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在“
Elsevier电子期刊
”中,
命中:
10,460
条,耗时:小于0.01 秒
在所有数据库中总计命中:
13,489
条
1.
Rapamycin inhibits
mTO
R/p70S6K activation in CA3 region of the hippocampus of the rat and impairs long term memory
作者:
D. Lana
a
;
J. Di Russo
b
;
T. Mello
c
;
G.L. Wenk
d
;
M.G. Giovannini
a
;
mariagrazia.giovannini@unifi.it
关键词:
ACQ
;
acquisition
;
ACh
;
acetylcholine
;
DMSO
;
dimethyl sulfoxide
;
IA
;
inhibitory avoidance
;
i.c.v.
;
intracerebroventricular
;
i.p.
;
intraperitoneal
;
mTO
R
;
mammalian Target of Rapamycin
;
mAChR
;
muscarinic acetylcholine receptors
;
mTO
RC1
2 ;
mammalian Target of Rapamycin Complex 1
2 ;
MEC
;
mecamylamine
;
nAChR
;
nicotinic acetylcholine receptors
;
p70S6K
;
p70S6Kinase
;
P-
mTO
R
;
phospho-
mTO
R
;
P-p70S6K
;
phospho-p70S6K
;
RAPA
;
rapamycin
;
SCOP
;
scopolamine
;
SEM
;
standard error of the mean
刊名:Neurobiology of Learning and Memory
出版年:2017
2.
The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of
mTO
RC1
作者:
Barbara Kathage
a
;
Sebastian Gehlert
b
;
Anna Ulbricht
a
;
Laura Lü
;
decke
a
;
Victor E. Tapia
c
;
Zacharias Orfanos
a
;
Daniela Wenzel
d
;
Wilhelm Bloch
b
;
Rudolf Volkmer
c
;
Bernd K. Fleischmann
d
;
Dieter O. Fü
;
rst
a
;
& Jö
;
rg Hö
;
hfeld
a
;
hoehfeld@uni-bonn.de
关键词:
BAG3
;
BCL2-associated athanogene
;
mTO
R
;
mammalian target of rapamycin
;
mTO
RC1
;
mammalian target of rapamycin complex 1
;
TSC
;
tuberous sclerosis
;
CASA
;
chaperone-assisted selective autophagy
;
CMA
;
chaperone-mediated autophagy
;
RE
;
maximal eccentric resistance exercise
;
ES
;
electrical stimulation
;
MBP
;
maltose-binding protein
;
CBD
;
chitin-binding domain
刊名:Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
出版年:2017
3.
Metformin Inhibits Hepatic
mTO
RC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex
作者:
Jessica J. Howell
1
;
4
;
Kristina Hellberg
2
;
4
;
Marc Turner
1
;
George Talbott
1
;
Matthew J. Kolar
3
;
Debbie S. Ross
2
;
Gerta Hoxhaj
1
;
Alan Saghatelian
3
;
Reuben J. Shaw
2
;
shaw@salk.edu
;
Brendan D. Manning
1
;
5
;
bmanning@hsph.harvard.edu
关键词:
metformin
;
AMPK
;
tuberous sclerosis complex
;
TSC1
;
TSC2
;
mTO
R
;
mTO
RC1
;
liver
;
hepatocytes
;
protein synthesis
刊名:Cell Metabolism
出版年:2017
4.
Kinetic modelling of in vitro data of PI3K,
mTO
R1, PTEN enzymes and on-target inhibitors Rapamycin, BEZ235, and LY294002
作者:
Alexey Goltsov
a
;
a.goltsov@abertay.ac.uk
;
Ghassan Tashkandi
b
;
s1163633@exseed.ed.ac.uk
;
Simon P. Langdon
b
;
Simon.Langdon@ed.ac.uk
;
David J. Harrison
c
;
David.Harrison@st-andrews.ac.uk
;
James L. Bown
a
;
d
;
j.bown@abertay.ac.uk
关键词:
Kinetic modelling
;
PI3K
;
mTO
R1
;
PTEN
;
Rapamycin
;
BEZ235
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
5.
mTO
R activation is critical for betulin treatment in renal cell carcinoma cells
作者:
Wenlong Cheng
a
;
Shiqi Ji
a
;
Haijian Zhang
a
;
Zhixing Han
a
;
Qingjun Liu
a
;
Jianwen Wang
b
;
Hao Ping
b
;
haopingcyh@163.com
关键词:
Betulin
;
mTO
R
;
Renal cell carcinoma
刊名:Biochemical and Biophysical Research Communications
出版年:2017
6.
Target regulation of PI3K/Akt/
mTO
R pathway by cannabidiol in treatment of experimental multiple sclerosis
作者:
Sabrina Giacoppo
a
;
Federica Pollastro
b
;
Gianpaolo Grassi
c
;
Placido Bramanti
a
;
Emanuela Mazzon
a
;
emazzon.irccs@gmail.com
关键词:
Cannabidiol
;
Multiple sclerosis
;
PI3K/Akt/
mTO
R pathway
;
BDNF
;
Inflammation
;
Neuronal survival
刊名:Fitoterapia
出版年:2017
7.
mTO
R Inhibition Mitigates Molecular and Biochemical Alterations of Vigabatrin-Induced Visual Field Toxicity in Mice
作者:
Kara R. Vogel
;
PhD
a
;
Garrett R. Ainslie
;
PhD
a
;
Michelle A. Schmidt
;
MS
b
;
Jonathan P. Wisor
;
PhD
b
;
K. Michael Gibson
;
PhD
a
;
mike.gibson@wsu.edu
关键词:
vigabatrin
;
GABA
;
mTO
R
;
gene expression
;
visual evoked potentials
;
visual field loss
;
ARPE19 cells
;
epilepsy
刊名:Pediatric Neurology
出版年:2017
8.
mTO
R up-regulation of PFKFB3 is essential for acute myeloid leukemia cell survival
作者:
Yonghuai Feng
a
;
b
;
c
;
d
;
1
;
yhfengpeking@126.com
;
Liusong Wu
e
;
1
关键词:
Acute myeloid leukemia
;
mTO
R
;
PFKFB3
刊名:Biochemical and Biophysical Research Communications
出版年:2017
9.
Molecular neurobiology of
mTO
R
作者:
Katarzyna Switon
a
;
Katarzyna Kotulska
b
;
Aleksandra Janusz-Kaminska
a
;
Justyna Zmorzynska
a
;
Jacek Jaworski
a
;
jaworski@iimcb.gov.pl
关键词:
4E-BPs
;
4E-binding proteins
;
Atg13
;
autophagy-related protein 13
;
BDNF
;
brain-derived neurotrophic factor
;
CGG
;
trinucleotide
;
EGF
;
epidermal growth factor
;
FXS
;
Fragile X syndrome
;
Hif1α
;
hypoxia-inducible factor 1-α
;
LTD
;
long-term depression
;
LTP
;
long-term potentiation
;
MAMs
;
mitochondrion-associated membranes
;
mTO
R
;
mammalian/mechanistic target of rapamycin
;
NSC
;
neural stem cell
;
p70S6K1
;
p70 ribosomal S6 protein kinase 1
;
PKC
;
protein kinase C
;
Rheb
;
Ras homolog enriched in brain protein
刊名:Neuroscience
出版年:2017
10.
PDMP, a ceramide analogue, acts as an inhibitor of
mTO
RC1 by inducing its translocation from lysosome to endoplasmic reticulum
作者:
Takashi Ode
a
;
b
;
Katarzyna A. Podyma-Inoue
c
;
Kazue Terasawa
c
;
Jin-ichi Inokuchi
d
;
Toshihide Kobayashi
e
;
f
;
Tetsuro Watabe
c
;
Yuichi Izumi
a
;
Miki Hara-Yokoyama
c
;
m.yokoyama.bch@tmd.ac.jp
关键词:
PDMP
;
mTO
R
;
Subcellular localization
;
Lysosome
;
ER
;
Osteoblast
刊名:Experimental Cell Research
出版年:2017
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