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Wiley电子期刊(14)
SpringerLink电子期刊(117)
ACS电子期刊(17)
Springer电子图书(2)
Elsevier电子期刊(108)
在“
Elsevier电子期刊
”中,
命中:
108
条,耗时:0.0509448 秒
在所有数据库中总计命中:
258
条
1.
Application of target-
mediated
drug
disposition
model to predict human pharmacokinetics and target occupancy of GC1118, an anti-epidermal growth factor receptor antibody
作者:
Wan-Su Park
1
;
2
;
Seunghoon Han
1
;
2
;
Jongtae Lee
1
;
2
;
Taegon Hong
3
;
Dong-Seok Yim
1
;
2
刊名:
Drug
Metabolism and Pharmacokinetics
出版年:2017
2.
Investigation of metabolism and
disposition
of Pf-05212377: Unexpected sulfonamide hydrolysis explains the lack of ketoconazole
mediated
DDI
作者:
Aarti Sawant-Basak
1
;
R. Scott Obach
2
;
Angela C. Doran
2
;
Hongying Gao
2
;
Klaas Schildknegt
3
;
Peter Lockwood
4
;
Jessica Mancuso
2
;
Susanna Tse
2
;
Thomas Comery
1
刊名:
Drug
Metabolism and Pharmacokinetics
出版年:2017
3.
The impact of Organic Anion-Transporting Polypeptides (OATPs) on
disposition
and toxicity of antitumor
drug
s: Insights from knockout and humanized mice
作者:
Selvi Durmus
a
;
1
;
Sté
;
phanie van Hoppe
b
;
1
;
Alfred H. Schinkel
b
;
a.schinkel@nki.nl" class="auth_mail" title="E-mail the corresponding author
关键词:
ABC
;
ATP-binding cassette
;
AUC
;
area under the concentration-time curve
;
DDI
;
drug
&ndash
;
drug
interactions
;
E2G
;
estradiol 17β-d-glucuronide
;
i.v.
;
intravenous
;
OATP
;
organic anion-transporting polypeptide
;
TKI
;
tyrosine kinase inhibitor
;
UGT1A1
;
UDP-glucuronosyltransferase 1A1
刊名:
Drug
Resistance Updates
出版年:2016
4.
An update on the role of intestinal cytochrome P450 enzymes in
drug
disposition
作者:
Fang Xie
a
;
Xinxin Ding
b
;
Qing-Yu Zhang
c
;
qing-yu.zhang@health.ny.gov" class="auth_mail" title="E-mail the corresponding author
关键词:
AUC
;
area under concentration-time curve
;
CPR
;
NADPH-cytochrome P450 reductase
;
DDI
;
drug
&ndash
;
drug
interaction
;
GFJ
;
grapefruit juice
;
IECN
;
intestinal epithelium-specific Cpr-null
;
LCN
;
liver-specific Cpr-null
;
P450 (or CYP)
;
cytochrome P450
;
P-gp
;
P-glycoprotein
;
WT
;
wide-type
刊名:Acta Pharmaceutica Sinica B
出版年:2016
5.
Functional expression of nicotine influx transporter in A549 human alveolar epithelial cells
作者:
Yuma Tega
a
;
1
;
d1361305@ems.u-toyama.ac.jp" class="auth_mail" title="E-mail the corresponding author
;
Chihiro Yuzurihara
a
;
1
;
s1060253@ems.u-toyama.ac.jp" class="auth_mail" title="E-mail the corresponding author
;
Yoshiyuki Kubo
a
;
kuboyosh@pha.u-toyama.ac.jp" class="auth_mail" title="E-mail the corresponding author
;
Shin-ichi Akanuma
a
;
akanumas@pha.u-toyama.ac.jp" class="auth_mail" title="E-mail the corresponding author
;
Carsten Ehrhardt
b
;
ehrhardc@tcd.ie" class="auth_mail" title="E-mail the corresponding author
;
Ken-ichi Hosoya
a
;
hosoyak@pha.u-toyama.ac.jp" class="auth_mail" title="E-mail the corresponding author
关键词:
Nicotine
;
Drug
transport
;
Respiratory epithelium
;
Inhalation biopharmaceutics
;
Pulmonary
drug
disposition
;
Bronchodilator
刊名:
Drug
Metabolism and Pharmacokinetics
出版年:2016
6.
In vivo Target Residence Time and Kinetic Selectivity: The Association Rate Constant as Determinant
作者:
Wilhelmus E.A. de Witte
1
;
Meindert Danhof
1
;
Piet H. van der Graaf
1
;
2
;
Elizabeth C.M. de Lange
1
;
ecmdelange@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author
关键词:
pharmacokinetics
;
target binding kinetics
;
kinetic selectivity
;
in vivo
;
association rate constant
;
target-
mediated
drug
disposition
刊名:Trends in Pharmacological Sciences
出版年:2016
7.
Enhancement of site specific delivery of diloxanide furoate as an antiamoebic
drug
作者:
Vaibhav Tiwari
a
;
Shekhar Verma
b
;
shekharpharma@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Santosh K. Verma
c
;
vermasantosh08@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Jawahar S. Dangi
a
关键词:
Colon
;
Pectin
;
Zn acetate
;
Diloxanide furoate
;
X-ray imaging
刊名:European Journal of Pharmaceutical Sciences
出版年:2016
8.
Serum- and glucocorticoid-inducible kinase SGK2 regulates human organic anion transporters 4 via ubiquitin ligase Nedd4-2
作者:
Haoxun Wang
a
;
Da Xu
a
;
May Fern Toh
a
;
Alan C. Pao
b
;
Guofeng You
a
;
gyou@rci.rutgers.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Organic anion transporter
;
Drug
transport
;
Regulation
;
Serum and glucocorticoid-inducible kinase
;
Ubiquitin ligase
;
Ubiquitination
刊名:Biochemical Pharmacology
出版年:2016
9.
Prostaglandin transporter (OATP2A1/SLCO2A1) contributes to local
disposition
of eicosapentaenoic acid-derived PGE
3
作者:
Tomoka Gose
;
Takeo Nakanishi
;
Shunsuke Kamo
;
Hiroaki Shimada
;
Katsumasa Otake
;
Ikumi Tamai
;
tamai@p.kanazawa-u.ac.jp" class="auth_mail" title="E-mail the corresponding author
关键词:
NSAIDs
;
non-steroidal anti-inflammatory
drug
s
;
EPA-E
;
eicosapentaenoic acid ethyl ester
;
AA
;
arachidonic acid
;
PGE2
;
prostaglandin E2
;
PGE3
;
prostaglandin E3
;
EP
;
PGE receptor
;
OATP
;
organic anion transporting polypeptide
;
OAT
;
organic anion transporter
;
OCT
;
organic cation transporter
;
MRP4
;
multi
drug
resistance-associated protein 4
;
LPS
;
lipopolysaccharide
;
COX
;
cyclooxygenase
刊名:Prostaglandins and Other Lipid Mediators
出版年:2016
10.
A novel pharmacokinetic model based on the complex elimination of monoclonal antibodies for bevacizumab pharmacokinetic study in rabbits
作者:
Lei Wang
;
Shan Ji
;
Meizhen Li
;
Zeneng Cheng
;
chengzn@csu.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
ADCC
;
antibody dependent cellular cytotoxicity
;
AUC
;
area under the concentration&ndash
;
time curve
;
CL
;
clearance
;
mAbs
;
monoclonal antibodies
;
M&ndash
M ;
Michaelis&ndash
;
Menten
;
PBS
;
phosphate-buffered saline
;
PK
;
pharmacokinetic
;
TMB
;
tetramethylbenzidine
;
TMDD
;
target-
mediated
drug
disposition
;
T1/2
;
half life
;
V
;
apparent volume of distribution
;
VEGF
;
vascular endothelial growth factor
刊名:International Immunopharmacology
出版年:2016
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7
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