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在“
Elsevier电子期刊
”中,
命中:
1,263
条,耗时:0.096958 秒
在所有数据库中总计命中:
2,050
条
1.
Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non-Small-Cell Lung Cancer and Activating
Epidermal
Growth
Factor
Receptor
Mutations
作者:
Natasha B. Leighl
1
;
Naiyer A. Rizvi
2
;
Lopes Gilberto de Lima Jr.
3
;
4
;
Wichit Arpornwirat
5
;
Charles M. Rudin
6
;
Alberto A. Chiappori
7
;
Myung-Ju Ahn
8
;
Laura Q.M. Chow
9
;
Lyudmila Bazhenova
10
;
Arunee Dechaphunkul
11
;
Patrapim Sunpaweravong
12
;
Keith Eaton
13
;
14
;
Jihong Chen
15
;
Sonja Medley
15
;
Srinivasu Poondru
15
;
Margaret Singh
15
;
Joyce Steinberg
15
;
Rosalyn A. Juergens
16
;
juergensr@hhsc.ca
;
Shirish M. Gadgeel
17
;
18
关键词:
Combination
;
Epidermal
growth
factor
receptor
inhibitor
;
First-line therapy
;
Insulin-like
growth
factor
-1
inhibitor
;
Tyrosine kinase
inhibitor
刊名:Clinical Lung Cancer
出版年:2017
2.
Ganglioside GM3 Mediates Glucose-Induced Suppression of IGF-1
Receptor
-Rac1 Activation to Inhibit Keratinocyte Motility
作者:
Duncan Hieu M. Dam
1
;
2
;
Xiao-Qi Wang
1
;
2
;
Sarah Sheu
1
;
Mahima Vijay
1
;
Desmond Shipp
1
;
Luke Miller
1
;
Amy S. Paller
1
;
apaller@northwestern.edu
关键词:
AS
;
antisense oligonucleotide
;
GCS
;
glucosylceramide synthase
;
GCSI
;
glucosylceramide synthase
inhibitor
;
GM3S
;
ganglioside GM3 synthase
;
IGF-1
;
insulin-like
growth
factor
-1
;
IGF1R
;
insulin-like
growth
factor
-1
receptor
;
IR
;
insulin
receptor
;
M2D3
;
GM2/GD2 and GD3 synthases
;
NHEK
;
normal human
epidermal
keratinocyte
;
shRNA
;
short hairpin RNA
;
siRNA
;
small interfering RNA
;
SNA
;
spherical nucleic acid
刊名:Journal of Investigative Dermatology
出版年:2017
3.
Senescence as biologic endpoint following pharmacological targeting of
receptor
tyrosine kinases in cancer
作者:
Paola Francica
;
Daniel M. Aebersold
;
Michaela Medová
;
;
michaela.medova@dkf.unibe.ch
关键词:
ATIR
;
anti-tumor immune response
;
ATM
;
ataxia telangiectasia mutated
;
CDK
;
cyclin-dependent kinase
;
CGH
;
comparative genomic hybridization
;
CHK1
;
checkpoint kinase 1
;
CHK2
;
checkpoint kinase 2
;
DDAs
;
DNA-damaging agents
;
DDR
;
DNA damage response
;
DSBs
;
double-strand breaks
;
EGF
;
epidermal
growth
factor
;
EGFR
;
epidermal
growth
factor
receptor
;
EPHA3
;
EPH
Receptor
A3
;
FGFR
;
fibroblast
growth
factor
receptor
;
FOXM1
;
Forkhead box protein M1
;
GAS6
;
growth
arrest-specific protein 6
;
H3K9me3
;
histone 3
刊名:Biochemical Pharmacology
出版年:2017
4.
Survival of Asian Females With Advanced Lung Cancer in the Era of Tyrosine Kinase
Inhibitor
Therapy
作者:
Daniel J. Becker
1
;
2
;
daniel.becker@nyumc.org
;
Juan P. Wisnivesky
3
;
Michael L. Grossbard
2
;
Abraham Chachoua
2
;
D. Ross Camidge
4
;
Benjamin P. Levy
3
关键词:
Epidermal
growth
factor
receptor
;
Ethnic disparities
;
Outcome research
;
SEER
;
TKIs
刊名:Clinical Lung Cancer
出版年:2017
5.
Shikonin inhibits gefitinib-resistant non-small cell lung cancer by inhibiting TrxR and activating the EGFR proteasomal degradation pathway
作者:
Xia Li
1
;
Xing-Xing Fan
1
;
Ze-Bo Jiang
;
Wings TY Loo
;
Xiao-Jun Yao
;
Elaine Lai-Han Leung
;
lhleung@must.edu.mo
;
Louis WC Chow
;
wcchow@must.edu.mo
;
Liang Liu
;
lliu@must.edu.mo
关键词:
NSCLC
;
non-small cell lung cancer cell
;
ROS
;
reactive oxygen species
;
EGFR
;
epidermal
growth
factor
receptor
;
T790M
;
a substitution mutation of threonine with methionine at position 790 of EGFR
;
TrxR
;
thioredoxin reductases
;
MTT
;
3-(4
;
5-dimetrylthiazol)-2
;
5-diphenyltetrazolium bromide
;
DCFDA
;
dichlorofluorescein diacetate
;
PBS
;
phosphate-buffered saline
;
RIPA
;
radioimmunoprecipitation assay
;
PARP
;
poly (ADP-ribosyl) polymerase
;
NAC
;
N-acetyl-l-cysteine
;
MG132
;
proteasomal degradation pathway inh
刊名:Pharmacological Research
出版年:2017
6.
An autopsy case of bronchiolitis obliterans as a previously unrecognized adverse event of afatinib treatment
作者:
Nobuhiro Kanaji
;
MD
;
PhD
a
;
kanaji@med.kagawa-u.ac.jp
;
Yoichi Chiba
;
MD
;
PhD
b
;
ychiba@med.kagawa-u.ac.jp
;
Akira Sato
;
MD
;
PhD
c
;
satoh@kagawa.coop
;
Masaki Ueno
;
MD
;
PhD
b
;
masaueno@med.kagawa-u.ac.jp
;
Akira Tadokoro
;
MD
;
PhD
a
;
tadokoro@med.kagawa-u.ac.jp
;
Nobuyuki Kita
;
MD
a
;
kitan0@med.kagawa-u.ac.jp
;
Tomoya Ishii
;
MD
;
PhD
a
;
tishii@med.kagawa-u.ac.jp
;
Naoki Watanabe
;
MD
a
;
naoki-w@med.kagawa-u.ac.jp
;
Norimitsu Kadowaki
;
MD
;
PhD
a
;
kado@med.kagawa-u.ac.jp
;
Shuji Bandoh
;
MD
;
PhD
a
;
sbandoh@med.kagawa-u.ac.jp
关键词:
BO
;
bronchiolitis obliterans
;
TKI
;
tyrosine kinase
inhibitor
;
EGFR
;
epidermal
growth
factor
receptor
;
NSCLC
;
non-small cell lung cancer
;
ILD
;
interstitial lung disease
;
FEV1
;
forced expiratory volume in 1s
刊名:Respiratory Investigation
出版年:2017
7.
Systematic Identification of Oncogenic EGFR Interaction Partners
作者:
Julia Petschnigg
1
;
Max Kotlyar
2
;
Louise Blair
1
;
Igor Jurisica
2
;
3
;
4
;
5
;
Igor Stagljar
6
;
7
;
8
;
Robin Ketteler
1
;
r.ketteler@ucl.ac.uk
关键词:
EGF
;
epidermal
growth
factor
;
EGFR
;
epidermal
growth
factor
receptor
;
ERK
;
extracellular signal-regulated kinase
;
GFP
;
green fluorescent protein
;
Grb2
;
growth
factor
receptor
-bound protein 2
;
SH
;
Src homology
;
MAPK
;
mitogen-activated protein kinase
;
TK
;
tyrosine kinase
;
TKI
;
TK
inhibitor
;
NSCLC
;
non-small cell lung cancer
;
MaMTH
;
mammalian membrane two-hybrid
;
TACC
;
transforming acidic coiled-coil protein
;
GO
;
gene ontology
;
Cub
;
C-terminal half of ubiquitin
;
TF
;
transcription
factor
;
Nub
;
N-ter
刊名:Journal of Molecular Biology
出版年:2017
8.
The Na
+
-D-glucose cotransporters SGLT1 and SGLT2 are targets for the treatment of diabetes and cancer
作者:
Hermann Koepsell
Hermann@koepsell.de
关键词:
AMG
;
α-methyl-D-glucopyranoside
;
BBB
;
blood brain barrier
;
BBM
;
brush-border membrane
;
BLM
;
basolateral membrane
;
CREB
;
cAMP response element binding protein
;
DNJ
;
1-deoxynojirimycin
;
EKA
;
euglycemic ketoacidosis
;
GGM
;
glucose-galactose malabsorption
;
GIP
;
glucose-dependent insulinotropic peptide
;
GLP-1
;
glucagon like peptide 1
;
GLP-2
;
glucagon like peptide 2
;
EGF
;
epidermal
growth
factor
;
EGFR
;
EGF
receptor
;
GIP
;
glucose-dependent insulinotropic hormone
;
GMI
;
genital mycotic infection
;
GFR
;
glo
刊名:Pharmacology & Therapeutics
出版年:2017
9.
Tyrosine kinase/phosphatase
inhibitor
s decrease dengue virus production in HepG2 cells
作者:
Thawornchai Limjindaporn
a
;
thawornchai.lim@mahidol.ac.th
;
Jutatip Panaampon
a
;
Shilu Malakar
b
;
Sansanee Noisakran
c
;
Pa-thai Yenchitsomanus
d
关键词:
Epidermal
growth
factor
receptor
inhibitor
;
Protein tyrosine phosphatase
inhibitor
;
Antiviral activity
;
Dengue virus
;
HepG2 cells
刊名:Biochemical and Biophysical Research Communications
出版年:2017
10.
Evolution and Increasing Complexity of the Therapeutic Landscape in Advanced Non-Small-cell Lung Cancer
作者:
David R. Gandara
;
drgandara@ucdavis.edu
;
Jonathan W. Riess
;
Karen Kelly
;
Tianhong Li
;
Philip C. Mack
;
Primo N. Lara Jr.
关键词:
Epidermal
growth
factor
receptor
;
NSCLC
;
Targeted therapy
;
Therapeutic landscape
;
Tyrosine kinase
inhibitor
刊名:Clinical Lung Cancer
出版年:2017
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