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Elsevier电子期刊(28827)
在“
Elsevier电子期刊
”中,
命中:
28,827
条,耗时:0.0219879 秒
在所有数据库中总计命中:
28,827
条
1.
Simultaneous Inhibition of P
I3
Kδ and PI3Kα Induces ABC-DLBCL Regression by Blocking BCR-Dependent and -Independent Activation of NF-κB and AKT
作者:
Juliane Paul
1
;
5
;
Maurice Soujon
1
;
5
;
Antje M. Wengner
1
;
Sabine Zitzmann-Kolbe
1
;
Andrea Sturz
1
;
Katja Haike
1
;
Koh Hui Keng Magdalene
2
;
Sze Huey Tan
3
;
Martin Lange
1
;
Soo Yong Tan
2
;
6
;
Dominik Mumberg
1
;
Soon Thye Lim
4
;
Karl Ziegelbauer
1
;
Ningshu Liu
1
;
ningshu.liu@bayer.com
关键词:
P
I3
Kα
;
P
I3
Kδ
;
NF-κB
;
BCR
;
MYD88
;
CARD11
;
DLBCL
;
follicular lymphoma
;
ibrutinib-resistance
;
copanlisib
刊名:Cancer Cell
出版年:2017
2.
La inhibición de la P
I3
Kγ protege contra la miocardiopatía diabética en ratones
作者:
Angelo Maffei
a
;
Giuseppe Cifelli
a
;
Raimondo Carnevale
a
;
Roberta Iacobucci
a
;
Fabio Pallante
a
;
Valentina Fardella
a
;
Stefania Fardella
a
;
Emilio Hirsch
b
;
Giuseppe Lembo
a
;
c
;
Daniela Carnevale
a
;
c
;
Daniela.carnevale@uniroma1.it
关键词:
Diabetes mellitus
;
Miocardiopatí
a ;
Fá
;
rmacos en investigació
n ;
Proteí
;
na P
I3
Kγ
;
Rató
n
刊名:Revista Española de Cardiología
出版年:2017
3.
P
I3
Kγ Inhibition Protects Against Diabetic Cardiomyopathy in Mice
作者:
Angelo Maffei
a
;
Giuseppe Cifelli
a
;
Raimondo Carnevale
a
;
Roberta Iacobucci
a
;
Fabio Pallante
a
;
Valentina Fardella
a
;
Stefania Fardella
a
;
Emilio Hirsch
b
;
Giuseppe Lembo
a
;
c
;
Daniela Carnevale
a
;
c
;
Daniela.carnevale@uniroma1.it
关键词:
Diabetes mellitus
;
Cardiomyopathy
;
Investigational drugs
;
P
I3
Kγ protein
;
Mouse
刊名:Revista Española de Cardiología (English Edition)
出版年:2017
4.
Kinetic modelling of in vitro data of P
I3
K, mTOR1, PTEN enzymes and on-target inhibitors Rapamycin, BEZ235, and LY294002
作者:
Alexey Goltsov
a
;
a.goltsov@abertay.ac.uk
;
Ghassan Tashkandi
b
;
s1163633@exseed.ed.ac.uk
;
Simon P. Langdon
b
;
Simon.Langdon@ed.ac.uk
;
David J. Harrison
c
;
David.Harrison@st-andrews.ac.uk
;
James L. Bown
a
;
d
;
j.bown@abertay.ac.uk
关键词:
Kinetic modelling
;
P
I3
K
;
mTOR1
;
PTEN
;
Rapamycin
;
BEZ235
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
5.
Discovery of triazole aminopyrazines as a highly potent and selective series of P
I3
Kδ inhibitors
作者:
Ina Terstiege
a
;
Ina.Terstiege@astrazeneca.com
;
Matthew Perry
a
;
Jens Petersen
b
;
Christian Tyrchan
a
;
Tor Svensson
a
;
Helena Lindmark
b
;
Linda Ö
;
ster
b
关键词:
Phosphoinositide 3-kinase
;
P
I3
Kδ inhibitor
;
Aminopyrazine
;
Inflammation
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
6.
Target regulation of P
I3
K/Akt/mTOR pathway by cannabidiol in treatment of experimental multiple sclerosis
作者:
Sabrina Giacoppo
a
;
Federica Pollastro
b
;
Gianpaolo Grassi
c
;
Placido Bramanti
a
;
Emanuela Mazzon
a
;
emazzon.irccs@gmail.com
关键词:
Cannabidiol
;
Multiple sclerosis
;
P
I3
K/Akt/mTOR pathway
;
BDNF
;
Inflammation
;
Neuronal survival
刊名:Fitoterapia
出版年:2017
7.
Inhibiting P
I3
K-AKt signaling pathway is involved in antitumor effects of ginsenoside Rg3 in lung cancer cell
作者:
Qipeng Xie
a
;
1
;
Huaikai Wen
a
;
1
;
Qiong Zhang
b
;
Weihe Zhou
c
;
Xiaoming Lin
d
;
Deyao Xie
d
;
Yu Liu
d
;
48936053@qq.com
关键词:
Ginsenoside Rg3
;
Lung cancer
;
Apoptosis
;
P
I3
K/Akt
刊名:Biomedicine & Pharmacotherapy
出版年:2017
8.
SAR study of 5-alkynyl substituted quinazolin-4(3H)-ones as phosphoinositide 3-kinase delta (P
I3
Kδ) inhibitors
作者:
Manman Wei
a
;
c
;
1
;
Xi Zhang
b
;
1
;
Xiang Wang
b
;
Zilan Song
a
;
Jian Ding
b
;
Ling-Hua Meng
b
;
lhmeng@simm.ac.cn
;
Ao Zhang
a
;
c
;
aozhang@simm.ac.cn
关键词:
Chronic lymphocytic leukemia
;
P
I3
Kδ
;
Structure-activity relationship
;
5-Alkynyl
;
Quinazolinone
刊名:European Journal of Medicinal Chemistry
出版年:2017
9.
Epigallocatechin-3-gallate inhibits adipogenesis through down-regulation of PPARγ and FAS expression mediated by P
I3
K-AKT signaling in 3T3-L1 cells
作者:
Mengqing Wu
a
;
b
;
1
;
Dan Liu
a
;
b
;
1
;
Rong Zeng
a
;
b
;
1
;
Tao Xian
a
;
b
;
Yi Lu
a
;
b
;
Guohua Zeng
a
;
b
;
Zhangzetian Sun
c
;
Bowei Huang
c
;
Qiren Huang
a
;
b
;
qrhuang@ncu.edu.cn
关键词:
4E-BP1
;
4E-binding protein1
;
C/EBP
;
CCAAT/ enhancer binding proteins
;
EGCG
;
epigallocatechin-3-gallate
;
FAS
;
fatty acid synthase
;
FOXO1
;
forkhead box-O1
;
HFD
;
high fat diet
;
IGF
;
insulin-like growth factor
;
IR
;
insulin resistance
;
IRS1
;
insulin receptor substrate 1
;
MSCs
;
mesenchymal stem cells
;
PGC1
;
PPARγ coactivator 1
;
P
I3
K
;
phosphatidylinositol 3 kinase
;
PPARγ
;
peroxisome proliferator activated receptor γ
;
Rb
;
retinoblastoma protein
;
TG
;
triglyceride
;
TIF2
;
transcriptional intermediary facto
刊名:European Journal of Pharmacology
出版年:2017
10.
The unexpected teratogenicity of RXR antagonist UV
I3
003 via activation of PPARγ in Xenopus tropicalis
作者:
Jingmin Zhu
a
;
Amanda Janesick
b
;
Lijiao Wu
a
;
Lingling Hu
a
;
Weiyi Tang
b
;
Bruce Blumberg
b
;
Huahong Shi
a
;
hhshi@des.ecnu.edu.cn
关键词:
UV
I3
003
;
TPT
;
Peroxisome proliferator activated receptor γ
;
Retinoid X receptor
;
Teratogenicity
;
Xenopus
刊名:Toxicology and Applied Pharmacology
出版年:2017
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