设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
Wiley电子期刊(1)
SpringerLink电子期刊(2)
Elsevier电子期刊(22)
在“
Elsevier电子期刊
”中,
命中:
22
条,耗时:小于0.01 秒
在所有数据库中总计命中:
25
条
1.
Lymphocytes contribute to biliary injury and fibrosis in experimental xenobiotic-induced cholestasis
作者:
Nikita Joshi
a
;
b
;
c
;
Anna K. Kopec
b
;
c
;
Holly Cline-Fedewa
b
;
James P. Luyendyk
a
;
b
;
c
;
luyendyk@cvm.msu.edu
关键词:
ANIT
;
alpha
-
naphthylisothiocya
nate
;
CK-19
;
cytokeratin-19
;
ALT
;
alanine aminotransferase
;
ALP
;
alkaline phosphatase
;
TGFβ
;
transforming growth factor beta
;
COL1A1
;
type I collagen
;
ITGβ6
;
integrin beta 6
;
αVβ6
;
alpha
Vbeta6 integrin
;
PBC
;
primary biliary cirrhosis
;
PSC
;
primary sclerosing cholangitis
;
BDEC
;
bile duct epithelial cell
刊名:Toxicology
出版年:2017
2.
Effects of andrographolide on intrahepatic cholestasis induced by
alpha
-
naphthylisothiocya
nate in rats
作者:
Tanaporn Khamphaya
a
;
Piyachat Chansela
b
;
Pawinee Piyachaturawat
c
;
Apichart Suksamrarn
d
;
Michael H. Nathanson
e
;
Jittima Weerachayaphorn
c
;
e
;
jittima.wee@mahidol.ac.th" class="auth_mail" title="E-mail the corresponding author
;
jittima.weerachayaphorn@yale.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Alpha
-
naphthylisothiocya
nate (PubChem CID
;
11080)
;
Andrographolide (PubChem CID
;
5318517)
;
Carboxymethylcellulose Sodium (PubChem CID
;
23706213)
刊名:European Journal of Pharmacology
出版年:2016
3.
Alpha
-
naphthylisothiocya
nate impairs bile acid homeostasis through AMPK-FXR pathways in rat primary hepatocytes
作者:
Xiaojiaoyang Li
a
;
Runping Liu
c
;
Linxi Yu
a
;
Zihang Yuan
a
;
Rong Sun
d
;
Hang Yang
a
;
Luyong Zhang
a
;
b
;
Zhenzhou Jiang
a
;
b
;
beaglejiang@cpu.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
ANIT
;
alpha
-
naphthylisothiocya
nate
;
A1AR
;
A1 adenosine receptor
;
FXR
;
farnesoid X receptor
;
SHP
;
small heterodimer partner
;
Bsep
;
bile salt export pump
;
Mrp2
;
multidrug resistance-associated protein 2
;
Ntcp
;
Na+-dependent taurocholate cotransporter
;
Oatp2
;
organic anion transporters 2
;
Mrp3
;
multidrug resistance-associated protein 3
;
AMPK
;
AMP-activated protein kinase
;
LKB1
;
liver kinase B1
;
ERK1/2
;
extracellular regulated protein kinases 1/2
;
PKA
;
cyclic AMP dependent protein kinase
刊名:Toxicology
出版年:2016
4.
Target profiling analyses of bile acids in the evaluation of hepatoprotective effect of gentiopicroside on
ANIT
-induced cholestatic liver injury in mice
作者:
Xiaowen Tang
a
;
shs912vv@126.com
;
Qiaoling Yang
a
;
cherish0814@126.com
;
Fan Yang
a
;
sailseem1111@hotmail.com
;
Junting Gong
a
;
576621831@qq.com
;
Han Han
a
;
837270636@qq.com
;
Li Yang
a
;
b
;
yangli7951@hotmail.com
;
Zhengtao Wang
a
关键词:
Cholestasis
;
Alpha
-
naphthylisothiocya
nate (
ANIT
)
;
Gentiopicroside (GPS)
;
Bile acids (BAs)
;
Traditional Chinese Medicine
刊名:Journal of Ethnopharmacology
出版年:2016
5.
Inhibition of PAR-4 and P2Y
12
receptor-mediated platelet activation produces distinct hepatic pathologies in experimental xenobiotic-induced cholestatic liver disease
作者:
Nikita Joshi
a
;
c
;
Anna K. Kopec
b
;
c
;
Jessica L. Ray
b
;
James P. Luyendyk
a
;
b
;
c
;
luyendyk@cvm.msu.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
ANIT
;
alpha
-
naphthylisothiocya
nate
;
ADP
;
adenosine diphosphate
;
PAR
;
protease activated receptor
;
H&E
;
hematoxylin and eosin
;
CK-19
;
cytokeratin-19
;
ALT
;
alanine aminotransferase
;
TGFβ
;
transforming growth factor beta
;
COL1A1
;
type I collagen
;
ITGβ6
;
integrin beta 6
;
TIMP1
;
tissue inhibitor of matrix metalloproteinase 1
;
αIIbβ3
;
alpha
IIbbetaIIIintegrin
;
αVβ6
;
alpha
Vbeta6 integrin
刊名:Toxicology
出版年:2016
6.
Dioscin protects against
ANIT
-induced cholestasis via regulating Oatps, Mrp2 and Bsep expression in rats
作者:
Aijie zhang
a
;
c
;
zhangaijie1986@163.com" class="auth_mail" title="E-mail the corresponding author
;
Yongming Jia
a
;
yongmingjiahlj@126.com" class="auth_mail" title="E-mail the corresponding author
;
Qinghan Xu
a
;
xulianglinyao@126.com" class="auth_mail" title="E-mail the corresponding author
;
Changyuan Wang
a
;
b
;
wangcyuan@163.com" class="auth_mail" title="E-mail the corresponding author
;
Qi Liu
a
;
b
;
llaqii@yahoo.com.cn" class="auth_mail" title="E-mail the corresponding author
;
Qiang Meng
a
;
b
;
mengq531@yahoo.cn" class="auth_mail" title="E-mail the corresponding author
;
Jinyong Peng
a
;
b
;
jinyongpeng2005@163.com" class="auth_mail" title="E-mail the corresponding author
;
Huijun Sun
a
;
b
;
sunhuijun@hotmail.com" class="auth_mail" title="E-mail the corresponding author
;
Pengyuan Sun
a
;
spfar1004@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Xiaokui Huo
a
;
b
;
huoxiaokui@163.com" class="auth_mail" title="E-mail the corresponding author
;
Kexin Liu
a
;
b
;
kexinliu@dlmedu.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
ALT
;
alanine amiotransferase
;
ANIT
;
alpha
-
naphthylisothiocya
nate
;
AST
;
aspartate transaminase
;
BIL
;
bilirubin
;
Bsep
;
bile salt export pump
;
CMC-Na
;
carboxymethylcellulose sodium
;
E3S
;
estrone-3-sulfate
;
FXR
;
Farnesoid X receptor
;
IS
;
hydrochlorothiazide
;
LC-MS/MS
;
liquid chromatography-tandem mass spectrometry
;
Mrp
;
multidrug resistance-associated protein
;
Ntcp
;
Na+-taurocholate cotransporting polypeptide
;
Oatp
;
organic anion transporting polypeptide
;
qRT-PCR
;
Quantitive Real Time-polymerase cha
刊名:Toxicology and Applied Pharmacology
出版年:2016
7.
Endogenous glucocorticoids exacerbate cholestasis-associated liver injury and hypercholesterolemia in mice
作者:
Rick van der Geest
a
;
r.van.der.geest@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author
;
Amber B. Ouweneel
a
;
a.b.ouweneel@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author
;
Ronald J. van der Sluis
a
;
r.vandersluis@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author
;
Albert K. Groen
b
;
a.k.groen@umcg.nl" class="auth_mail" title="E-mail the corresponding author
;
Miranda Van Eck
a
;
m.eck@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author
;
Menno Hoekstra
a
;
hoekstra@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author
关键词:
ABCB4
;
ATP-binding cassette transporter B4
;
ADX
;
adrenalectomy
;
ALT/GPT
;
alanine transaminase/glutamic pyruvic transaminase
;
ANIT
;
alpha
-
naphthylisothiocya
nate
;
APOA4
;
apolipoprotein A4
;
BSEP/ABCB11
;
bile salt efflux pump
;
CYP7A1
;
cholesterol 7
alpha
-hydroxylase
;
FXR/BAR
;
farnesoid X receptor/bile acid receptor
;
HDL
;
high-density lipoprotein
;
HMGCR
;
HMG-CoA reductase
;
LDL
;
low-density lipoprotein
;
LDLR
;
low-density lipoprotein receptor
;
NTCP1/SLC10A1
;
sodium/bile acid cotransporter member 1
;
PEPC
刊名:Toxicology and Applied Pharmacology
出版年:2016
8.
A synthetic biology-based device prevents liver injury in mice
作者:
Peng Bai
1
;
Haifeng Ye
1
;
2
;
Mingqi Xie
1
;
Pratik Saxena
1
;
Henryk Zulewski
1
;
3
;
4
;
Ghislaine Charpin-El Hamri
5
;
Valentin Djonov
6
;
Martin Fussenegger
1
;
7
;
fussenegger@bsse.ethz.ch" class="auth_mail" title="E-mail the corresponding author
关键词:
HGF
;
hepatocyte growth factor
;
PKA
;
cAMP-dependent phosphokinase A
;
CRE
;
cAMP-response element
;
PCRE
;
CRE-containing synthetic mammalian promoter
;
SEAP
;
human placental secreted alkaline phosphatase
;
CREm
;
modified cAMP-response element
;
PCREm
;
modified PCRE variant
;
TUDCA
;
tauroursodeoxycholic acid
;
shGLP1
;
short human glucacon-like peptide 1
;
SBA
;
serum bile acid
;
CCl4
;
Carbon tetrachloride
;
ANIT
;
alpha
-
naphthylisothiocya
nate
刊名:Journal of Hepatology
出版年:2016
9.
Alpha
-
naphthylisothiocya
nate modulates hepatobiliary transporters in sandwich-cultured rat hepatocytes
作者:
Cen Guo
;
Lei He
;
Dan Yao
;
Jiye A
;
Bei Cao
;
Jin Ren
;
Guangji Wang
;
Guoyu Pan
关键词:
SCRH
;
sandwich-cultured rat hepatocytes
;
ANIT
;
alpha
-
naphthylisothiocya
nate
;
Mrp
;
multidrug resistance-associated protein
;
Bsep
;
bile salt export pump
;
Ntcp
;
sodium/taurocholate cotransporting polypeptide
;
Oatp
;
organic anion transporting polypeptide
;
BEI
;
biliary excretion index
;
Clbiliary
;
biliary clearance
;
IPRLs
;
isolated perfused rat livers
;
BECs
;
biliary epithelial cells
;
Cyp7a1
;
cholesterol 7伪-hydroxylase
;
Cyp27a1
;
sterol 27-hydroxylase
;
Cyp8b1
;
sterol 12伪-hydroxylase
;
CDF
;
5 (and 6)-ca
刊名:Toxicology Letters
出版年:3 January, 2014
10.
Characterization of animal models for primary sclerosing cholangitis (PSC)
作者:
Peter Fickert
1
;
2
;
&dagger
;
;
peter.fickert@medunigraz.at" class="auth_mail
;
Marion J. Pollheimer
1
;
2
;
&dagger
;
;
Ulrich Beuers
3
;
Carolin Lackner
2
;
Gideon Hirschfield
4
;
Chantal Housset
5
;
Verena Keitel
6
;
Christoph Schramm
7
;
Hanns-Ulrich Marschall
8
;
Tom H. Karlsen
9
;
10
;
11
;
12
;
Espen Melum
9
;
10
;
11
;
Arthur Kaser
13
;
Bertus Eksteen
14
;
Mario Strazzabosco
15
;
16
;
Michael Manns
17
;
Michael Trauner
18
;
michael.trauner@meduniwien.ac.at" class="auth_mail
;
for the International PSC Study Group (IPSCSG)
关键词:
ANA
;
anti-nuclear antibody
;
ANCA
;
anti-neutrophil cytoplasmic antibody
;
ANIT
;
alpha
-
naphthylisothiocya
nate
;
BA
;
bile acids
;
BDL
;
bile duct ligation
;
BEC
;
biliary epithelial cell
;
CCC
;
cholangiocellular carcinoma
;
Cftr
;
cystic fibrosis transmembrane conductance regulator
;
DC
;
dendritic cell
;
DDC
;
3
;
5-diethoxycarbonyl-1
;
4-dihydrocollidine
;
DSS
;
dextrane sodium sulfate
;
fch
;
ferrochelatase
;
fMLT
;
N-formyl L-methionine L-leucin L-tyrosine
;
GVHD
;
graft-vs.-host disease
;
h
;
hours
;
HSDH
;
3伪-hydroxyster
刊名:Journal of Hepatology
出版年:June 2014
1
2
3
按检索点细分(22)
关键词(11)
文摘(13)
按出版年细分(22)
2027年及以后(2)
2017年(1)
2016年(7)
2013年(1)
2012年(2)
2011年(2)
2010年(1)
2008年(1)
2007年(2)
2005年(1)
2000年及以前(2)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.