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在“
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57,068
条
1.
Singl
e
chain
Fc
-dim
e
r-human growth hormon
e
fusion prot
e
in for improv
e
d drug d
e
liv
e
ry
作者:
Li Zhou
a
;
Hsuan-Yao Wang
a
;
Shanshan Tong
a
;
b
;
Curtis T. Okamoto
a
;
W
e
i-Chiang Sh
e
n
a
;
w
e
ish
e
n@usc.
e
du
;
J
e
nnica L. Zaro
a
;
c
;
jZaro@w
e
stcoastuniv
e
rsity.
e
du
关键词:
Fc
fusion
;
Singl
e
chain
Fc
;
Prot
e
in d
e
liv
e
ry
;
Human growth hormon
e
;
Pharmacokin
e
tics
;
Pharmacodynamics
刊名:Biomat
e
rials
出版年:2017
2.
Charact
e
rization of
Fc
γRIIIA
e
ff
e
ctor c
e
lls us
e
d in in vitro ADCC bioassay: Comparison of primary NK c
e
lls with
e
ngin
ee
r
e
d NK-92 and Jurkat T c
e
lls
作者:
Yao-T
e
Hsi
e
h
a
;
yao-t
e
.hsi
e
h@pfiz
e
r.com
;
Poonam Aggarwal
a
;
1
;
poonam.aggarwal@pfiz
e
r.com
;
David Cir
e
lli
b
;
Ling Gu
b
;
T
e
r
e
sa Surowy
a
;
N
e
d M. Mozi
e
r
a
关键词:
mAbs
;
monoclonal antibodi
e
s
;
Fab
;
fragm
e
nt antig
e
n-binding
;
Fc
;
fragm
e
nt crystallizabl
e
;
NK c
e
lls
;
natural kill
e
r c
e
lls
;
ADCC
;
antibody-d
e
p
e
nd
e
nt c
e
ll-m
e
diat
e
d cytotoxicity
;
MOA
;
m
e
chanisms of action
;
NFAT
;
nucl
e
ar factor of activat
e
d T c
e
lls
;
T c
e
lls
;
thymocyt
e
c
e
lls
;
IgG1
;
immunoglobulin G1
;
Fc
R
;
Fc
r
e
c
e
ptor
;
IL-2
;
int
e
rl
e
ukin-2
;
ASN-297
;
asparagin
e
-297
;
V-158
;
valin
e
at amino acid 158
;
F-158
;
ph
e
nylalanin
e
at amino acid 158
;
E
GFR
;
e
pid
e
rmal growth factor r
e
c
e
ptor
;
AAF-Glo&trad
e
;
alanyl-alany
刊名:Journal of Immunological M
e
thods
出版年:2017
3.
MafB
e
nhanc
e
s th
e
phagocytic activity of RAW264.7 macrophag
e
s by promoting
Fc
gr3
e
xpr
e
ssion
作者:
Takako N
e
moto
;
Yoko Shibata
;
shibata@m
e
d.id.yamagata-u.ac.jp
;
Sumito Inou
e
;
Akira Igarashi
;
Yoshikan
e
Tokairin
;
K
e
iko Yamauchi
;
Tomomi Kimura
;
Masamichi Sato
;
K
e
nto Sato
;
Hiroshi Nakano
;
Shuichi Ab
e
;
Michiko Nishiwaki
;
Isao Kubota
关键词:
MafB
;
Fc
gr3
;
CD16
;
Macrophag
e
;
Phagocytosis
刊名:Bioch
e
mical and Biophysical R
e
s
e
arch Communications
出版年:2017
4.
Fc
fragm
e
nts of immunoglobulin G ar
e
an inductor of r
e
gulatory rh
e
umatoid factor and a promising th
e
rap
e
utic ag
e
nt for rh
e
umatic dis
e
as
e
s
作者:
Al
e
xandr Sidorov
;
Liubov B
e
dul
e
va
;
blv76@mail.ru
;
Igor M
e
nshikov
;
Al
e
x
e
y T
e
r
e
nti
e
v
;
E
l
e
na Stolyarova
;
Nad
e
zhda Abish
e
va
关键词:
R
e
gulatory rh
e
umatoid factor
;
Fc
fragm
e
nts
;
Antig
e
nic d
e
t
e
rminant
刊名:Int
e
rnational Journal of Biological Macromol
e
cul
e
s
出版年:2017
5.
Prot
e
ctiv
e
e
fficacy of
Fc
targ
e
ting cons
e
rv
e
d influ
e
nza virus M2
e
antig
e
n
e
xpr
e
ss
e
d by Lactobacillus plantarum
作者:
W
e
n-Tao Yang
1
;
Gui-Lian Yang
1
;
Qian Wang
;
Hai-Bin Huang
;
Yan-Long Jiang
;
Chun-W
e
i Shi
;
Jian-Zhong Wang
;
K
e
-Yan Huang
;
Yu-B
e
i Jin
;
Chun-F
e
ng Wang
;
wangchunf
e
ng@jlau.
e
du.cn
关键词:
Lactobacillus plantarum
;
Influ
e
nza virus
;
M2
e
;
N
e
onatal
Fc
r
e
c
e
ptor
刊名:Antiviral R
e
s
e
arch
出版年:2017
6.
Quantification and simultan
e
ous
e
valuation of th
e
bioactivity of antibody produc
e
d in CHO c
e
ll cultur
e
—Th
e
us
e
of th
e
e
ctodomain of
Fc
γRI and surfac
e
plasmon r
e
sonanc
e
-bas
e
d bios
e
nsor
作者:
July Dorion-Thibaud
e
au
a
;
b
;
Yv
e
s Duroch
e
r
b
;
c
;
1
;
yv
e
s.duroch
e
r@nrc-cnrc.gc.ca
;
Gr
e
gory D
e
Cr
e
sc
e
nzo
a
;
1
;
gr
e
gory.d
e
cr
e
sc
e
nzo@polymtl.ca
关键词:
Fc
γR
;
Monoclonal antibody
;
Surfac
e
plasmon r
e
sonanc
e
(SPR)
;
Bioproc
e
ss monitoring
刊名:Mol
e
cular Immunology
出版年:2017
7.
KI
FC
1 induc
e
s r
e
sistanc
e
to doc
e
tax
e
l and is associat
e
d with survival of pati
e
nts with prostat
e
canc
e
r
作者:
Yoh
e
i S
e
kino
;
M.D.
a
;
b
;
Naohid
e
Ou
e
;
M.D.
;
Ph.D.
a
;
naou
e
@hiroshima-u.ac.jp
;
Yoshinori Shig
e
matsu
;
M.D.
a
;
b
;
Akira Ishikawa
;
M.D.
a
;
Naoya Sakamoto
;
M.D.
;
Ph.D.
a
;
Kazuhiro S
e
ntani
;
M.D.
;
Ph.D.
a
;
Jun T
e
ishima
;
M.D.
;
Ph.D.
b
;
Akio Matsubara
;
M.D.
;
Ph.D.
b
;
Wataru Yasui
;
M.D.
;
Ph.D.
a
关键词:
Prostat
e
canc
e
r
;
KI
FC
1
;
Canc
e
r st
e
m c
e
lls
;
Doc
e
tax
e
l
刊名:Urologic Oncology: S
e
minars and Original Inv
e
stigations
出版年:2017
8.
S
e
l
e
ctivity
e
valuation and s
e
paration of human immunoglobulin G, Fab and
Fc
fragm
e
nts with mix
e
d-mod
e
r
e
sins
作者:
Ying-Di Luo
;
Qi-L
e
i Zhang
;
Xiao-Ming Yuan
;
W
e
i Shi
;
Shan-Jing Yao
;
Dong-Qiang Lin
;
lindq@zju.
e
du.cn
关键词:
Mix
e
d-mod
e
chromatography
;
Adsorption s
e
l
e
ctivity
;
S
e
paration
;
Human immunoglobulin G
;
Fc
fragm
e
nt
;
Fab fragm
e
nt
刊名:Journal of Chromatography B
出版年:2017
9.
Fc
-sp
e
cific biotinylation of antibody using an
e
ngin
ee
r
e
d photoactivatabl
e
Z-Biotin and its bios
e
nsing application
作者:
Hong-Ming Yang
;
Ru-M
e
ng Bao
;
Chang-M
e
i Yu
;
Yan-Na Lv
;
W
e
i-F
e
n Zhang
;
Jin-Bao Tang
;
tangjb@wfmc.
e
du.cn" class="auth_mail" titl
e
="E-mail th
e
corr
e
sponding author
;
tangjinbao2002@126.com" class="auth_mail" titl
e
="E-mail th
e
corr
e
sponding author
关键词:
Photoactivatabl
e
Z&ndash
;
Biotin
;
Fc
-sp
e
cific coval
e
nt conjugation
;
Immunoglobulin G
;
Biotin
;
Bios
e
nsing
刊名:Analytica Chimica Acta
出版年:2017
10.
Conv
e
rsion of a dir
e
ct to an indir
e
ct comm
e
rcial (H
FC
134a/CO
2
) cascad
e
r
e
frig
e
ration syst
e
m: En
e
rgy impact analysis
关键词:
Cascad
e
;
F-Gas
;
CO2
;
H
FC
134a
;
E
n
e
rgy analysis
刊名:Int
e
rnational Journal of R
e
frig
e
ration
出版年:2017
1
2
3
4
5
6
7
8
9
按检索点细分(36005)
题名(3468)
作者(1102)
关键词(2726)
文摘(31957)
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