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内部出版物
在“
Elsevier电子期刊
”中,
命中:
12
条,耗时:小于0.01 秒
1.
Increasing metabolic stability via the deuterium kinetic isotope effect: An example from a proline-amide-urea aminothiazole series of phosphatidylinositol-3 kinase alpha inhibitors
作者:
Robin A. Fairhurst
;
robin.fairhurst@novartis.com" class="auth_mail" title="E-mail the corresponding author
;
Giorgio
Caravatti
;
Vito Guagnano
;
Reiner Aichholz
;
Joachim Blanz
;
Francesca Blasco
;
Peter Wipfli
;
Christine Fritsch
;
Sauveur-Michel Maira
;
Christian Schnell
;
Frank H. Seiler
关键词:
Phosphatidylinositol-3 kinase alpha inhibitor
;
Deuterium kinetic isotope effect
;
Metabolism
;
Pharmacokinetics
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
2.
Corrigendum to ¡°Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation¡± [Bioorg. Med. Chem. Lett. 23 (2013) 3741-3748]
作者:
Pascal Furet
;
Vito Guagnano
;
Robin A. Fairhurst
;
Patricia Imbach-Weese
;
Ian Bruce
;
Mark Knapp
;
Christine Fritsch
;
Francesca Blasco
;
Joachim Blanz
;
Reiner Aichholz
;
Jacques Hamon
;
Doriano Fabbro
;
Giorgio
Caravatti
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
3.
Entry into a new class of protein kinase inhibitors by pseudo ring design
作者:
Pascal Furet
;
Giorgio
Caravatti
;
Vito Guagnano
;
Marc Lang
;
Thomas Meyer
;
Joseph Schoepfer
关键词:
Kinase
;
Scaffold morphing
;
Pseudo ring
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2008
4.
Convergent synthesis of potent peptide inhibitors of the Grb2-SH2 domain by palladium catalyzed coupling of a terminal alkyne
作者:
Schoepfer
;
Joseph
;
Gay
;
Brigitte
;
End
;
Nicole
;
Muller
;
Evelyne
;
Scheffel
;
Gisela
;
Caravatti
;
Giorgio
;
et. al.
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2001
5.
Synthesis of (+)-(
R
)-methyl 2-aminotetraline-2-carboxylate: the hydroxypinanone method versus the bislactim method
作者:
Solladié
;
-Cavallo
;
Arlette
;
Martin-Cabrejas
;
Luisa M.
;
Caravatti
;
Giorgio
;
Lang
;
Marc
刊名:Tetrahedron: Asymmetry
出版年:2001
6.
Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 2
作者:
Walker
;
Clive V.
;
Caravatti
;
Giorgio
;
Denholm
;
Alastair A.
;
Egerton
;
John
;
Faessler
;
Alex
;
et. al.
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2000
7.
Synthesis and biological evaluation of highly potent analogues of epothilones B and D
作者:
Altmann
;
Karl-Heinz
;
Bold
;
Guido
;
Caravatti
;
Giorgio
;
Flö
;
rsheimer
;
Andreas
;
Guagnano
;
Vito
;
et. al.
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2000
8.
Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 1
作者:
Furet
;
Pascal
;
Caravatti
;
Giorgio
;
Denholm
;
Alastair A.
;
Faessler
;
Alex
;
Fretz
;
Heinz
;
Garcí
;
a-Echeverrí
a ;
Carlos
;
et. al.
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2000
9.
Synthesis and biological evaluation of highly potent analogues of epothilones B and D
作者:
Altmann
;
Karl-Heinz
;
Bold
;
Guido
;
Caravatti
;
Giorgio
;
Flö
;
rsheimer
;
Andreas
;
Guagnano
;
Vito
;
et. al.
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2000
10.
Structure-based design of a non-peptidic antagonist of the SH2 domain of GRB2
作者:
Caravatti
;
Giorgio
;
Rahuel
;
Joseph
;
Gay
;
Brigitte
;
Furet
;
Pascal
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:1999
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