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内部出版物
在“
Elsevier电子期刊
”中,
命中:
242
条,耗时:小于0.01 秒
1.
Trastuzumab stimulation of ribosomal protein S6 kinase 1 (
S6K1
) predicts de novo trastuzumab resistance
作者:
Felicia C. Huynh
;
Daniel Nguyen
;
Frank E. Jones
;
fjones3@tulane.edu
关键词:
EGFR-family
;
Trastuzumab
;
Breast cancer
;
Therapeutic resistance
;
S6K1
;
Rapamycin
;
mTORC1
刊名:Biochemical and Biophysical Research Communications
出版年:2017
2.
Molecular neurobiology of mTOR
作者:
Katarzyna Switon
a
;
Katarzyna Kotulska
b
;
Aleksandra Janusz-Kaminska
a
;
Justyna Zmorzynska
a
;
Jacek Jaworski
a
;
jaworski@iimcb.gov.pl
关键词:
4E-BPs
;
4E-binding proteins
;
Atg13
;
autophagy-related protein 13
;
BDNF
;
brain-derived neurotrophic factor
;
CGG
;
trinucleotide
;
EGF
;
epidermal growth factor
;
FXS
;
Fragile X syndrome
;
Hif1α
;
hypoxia-inducible factor 1-α
;
LTD
;
long-term depression
;
LTP
;
long-term potentiation
;
MAMs
;
mitochondrion-associated membranes
;
mTOR
;
mammalian/mechanistic target of rapamycin
;
NSC
;
neural stem cell
;
p70
S6K1
;
p70 ribosomal S6 protein kinase 1
;
PKC
;
protein kinase C
;
Rheb
;
Ras homolog enriched in brain protein
刊名:Neuroscience
出版年:2017
3.
Functions of lysosomes are impaired during prolonged stress conditions in cells devoid of
S6K1
/2
作者:
Aleksandra Hac
;
Karolina Pierzynowska
;
Anna Herman-Antosiewicz
刊名:Molecular Genetics and Metabolism
出版年:2017
4.
Kinetic modelling of in vitro data of PI3K, mTOR1, PTEN enzymes and on-target inhibitors Rapamycin, BEZ235, and LY294002
作者:
Alexey Goltsov
a
;
a.goltsov@abertay.ac.uk
;
Ghassan Tashkandi
b
;
s1163633@exseed.ed.ac.uk
;
Simon P. Langdon
b
;
Simon.Langdon@ed.ac.uk
;
David J. Harrison
c
;
David.Harrison@st-andrews.ac.uk
;
James L. Bown
a
;
d
;
j.bown@abertay.ac.uk
关键词:
Kinetic modelling
;
PI3K
;
mTOR1
;
PTEN
;
Rapamycin
;
BEZ235
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
5.
S6K1
Is Required for Increasing Skeletal Muscle Force during Hypertrophy
作者:
Manuela Marabita
1
;
Martina Baraldo
1
;
Francesca Solagna
1
;
Judith Johanna Maria Ceelen
1
;
Roberta Sartori
1
;
Hendrik Nolte
2
;
Ivan Nemazanyy
4
;
Sté
;
phane Pyronnet
3
;
Marcus Kruger
2
;
Mario Pende
4
;
Bert Blaauw
1
;
5
;
6
;
bert.blaauw@unipd.it" class="auth_mail" title="E-mail the corresponding author
关键词:
skeletal muscle
;
hypertrophy
;
AKT
;
S6K1
;
rapamycin
;
p62
;
protein aggregates
;
muscle force
;
mTOR
刊名:Cell Reports
出版年:2016
6.
SAR study of 5-alkynyl substituted quinazolin-4(3H)-ones as phosphoinositide 3-kinase delta (PI3Kδ) inhibitors
作者:
Manman Wei
a
;
c
;
1
;
Xi Zhang
b
;
1
;
Xiang Wang
b
;
Zilan Song
a
;
Jian Ding
b
;
Ling-Hua Meng
b
;
lhmeng@simm.ac.cn
;
Ao Zhang
a
;
c
;
aozhang@simm.ac.cn
关键词:
Chronic lymphocytic leukemia
;
PI3Kδ
;
Structure-activity relationship
;
5-Alkynyl
;
Quinazolinone
刊名:European Journal of Medicinal Chemistry
出版年:2017
7.
Identification of novel FAK and
S6K1
dual inhibitors from natural compounds via ADMET screening and molecular docking
作者:
Varadharajan Thiyagarajan
1
;
Shin-Hung Lin
1
;
Yu-Chuan Chang
;
Ching-Feng Weng
;
cfweng@mail.ndhu.edu.tw" class="auth_mail" title="E-mail the corresponding author
关键词:
Virtual screening
;
FAK
;
S6K1
;
ADMET
;
Molecular docking
刊名:Biomedicine & Pharmacotherapy
出版年:2016
8.
Microcystin-LR promotes proliferation by activating Akt/
S6K1
pathway and disordering apoptosis and cell cycle associated proteins phosphorylation in HL7702 cells
作者:
Jinghui Liu
a
;
Hao Wang
b
;
Beilei Wang
a
;
Tao Chen
a
;
Xiaofeng Wang
c
;
Pu Huang
a
;
Lihong Xu
a
;
xulihong@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author
;
Zonglou Guo
d
;
zlguo@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
Microcystin-LR
;
Proliferation
;
PP2A
;
α4
;
Akt/
S6K1
刊名:Toxicology Letters
出版年:2016
9.
IL-2, IL-4, IFN-γ or TNF-α enhances BAFF-stimulated cell viability and survival by activating Erk1/2 and
S6K1
pathways in neoplastic B-lymphoid cells
作者:
Lin Gui
a
;
1
;
Qingyu Zeng
a
;
1
;
Zhigang Xu
a
;
1
;
Hai Zhang
a
;
Shanshan Qin
a
;
Chunxiao Liu
a
;
Chong Xu
a
;
Zhou Qian
a
;
Shuangquan Zhang
a
;
Shile Huang
b
;
c
;
Long Chen
a
;
lchen@njnu.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
Cytokine
;
BAFF
;
B cell
;
Erk1/2
;
S6K1
刊名:Cytokine
出版年:2016
10.
Zinc stimulates glucose consumption by modulating the insulin signaling pathway in L6 myotubes: essential roles of Akt-GLUT4, GSK3β and mTOR-
S6K1
作者:
Yuntang Wu
a
;
1
;
Wuyuntang@tmu.edu.cn" class="auth_mail" title="E-mail the corresponding author
;
Huizi Lu
b
;
1
;
Huijun Yang
a
;
Chunlei Li
a
;
Qian Sang
a
;
Xinyan Liu
a
;
Yongzhe Liu
c
;
Yongming Wang
c
;
Zhong Sun
d
;
关键词:
AMPK
;
AMP-activated protein kinase
;
DMEM
;
Dulbecco's modified Eagle's medium
;
FBS
;
fetal bovine serum
;
GLUT4
;
glucose transporter 4
;
IR
;
insulin receptor
;
GS
;
glycogen synthase
;
HS
;
horse serum
;
IRS
;
insulin receptor substrate
;
MAPK
;
mitogen-activated protein kinase
;
mTOR
;
mammalian target of rapamycin
;
PI3K
;
phosphatidylinositol 3-kinase pathway
;
S6 K1
;
ribosomal protein S6 kinase
;
polypeptide 1
;
SDS
;
sodium dodecyl sulfate
刊名:Journal of Nutritional Biochemistry
出版年:2016
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