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内部出版物
在“
Elsevier电子期刊
”中,
命中:
4,259
条,耗时:小于0.01 秒
1.
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results
作者:
Alison Margolskee
a
;
alison.margolskee@manchester.ac.uk
;
Adam S. Darwich
a
;
Xavier Pepin
b
;
c
;
Leon Aarons
a
;
Aleksandra Galetin
a
;
Amin Rostami-Hodjegan
a
;
d
;
Sara Carlert
e
;
Maria Hammarberg
e
;
Constanze Hilgendorf
e
;
Pernilla Johansson
e
;
Eva Karlsson
e
;
Dó
;
nal Murphy
b
;
Christer Tannergren
e
;
Helena Thö
;
rn
e
;
Mohammed Yasin
b
;
Florent Mazuir
c
;
Olivier Nicolas
c
;
Sergej Ramusovic
f
;
Christine Xu
g
;
Shriram M. Pathak
d
;
Timo Korjamo
h
;
Johanna
Laru
b
;
h
;
Jussi Malkki
h
;
Sari Pappinen
h
;
Johanna
Tuunainen
h
;
Jennifer Dressman
i
;
Simone Hansmann
i
;
Edmund Kostewicz
i
;
Handan He
j
;
Tycho Heimbach
j
;
Fan Wu
j
;
Carolin Hoft
k
;
Loic Laplanche
k
;
Yan Pang
k
;
Michael B. Bolger
l
;
Eva Huehn
l
;
Viera Lukacova
l
;
James M. Mullin
l
;
Ke X. Szeto
l
;
Chester Costales
m
;
Jian Lin
m
;
Mark McAllister
n
;
Sweta Modi
m
;
Charles Rotter
m
;
Manthena Varma
n
;
Mei Wong
n
;
Amitava Mitra
o
;
Jan Bevernage
p
;
Jeike Biewenga
p
;
Achiel Van Peer
p
关键词:
API
;
Active pharmaceutical ingredient
;
AUC
;
Area under the curve
;
BCS
;
Biopharmaceutics classification system
;
BE
;
Bioequivalence
;
BP
;
Blood-to-plasma ratio
;
CL
;
Clearance
;
CL/F
;
Apparent clearance
;
Cmax
;
Maximum concentration
;
Do
;
Dose number
;
fa
;
Fraction absorbed
;
FIM
;
First in man
;
Foral
;
Absolute oral bioavailability
;
Frel
;
Relative bioavailability
;
fup
;
Fraction unbound in plasma
;
IMI
;
Innovative Medicines Initiative
;
i.v.
;
Intravenous
;
IR
;
Immediate release
;
LogP
;
Logarithm of the octanol
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
2.
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes
作者:
Adam S. Darwich
a
;
Alison Margolskee
a
;
alison.margolskee@manchester.ac.uk
;
Xavier Pepin
b
;
c
;
Leon Aarons
a
;
Aleksandra Galetin
a
;
Amin Rostami-Hodjegan
a
;
d
;
Sara Carlert
e
;
Maria Hammarberg
e
;
Constanze Hilgendorf
e
;
Pernilla Johansson
e
;
Eva Karlsson
e
;
Dó
;
nal Murphy
b
;
Christer Tannergren
e
;
Helena Thö
;
rn
e
;
Mohammed Yasin
b
;
Florent Mazuir
c
;
Olivier Nicolas
c
;
Sergej Ramusovic
f
;
Christine Xu
g
;
Shriram M. Pathak
d
;
Timo Korjamo
h
;
Johanna
Laru
b
;
h
;
Jussi Malkki
h
;
Sari Pappinen
h
;
Johanna
Tuunainen
h
;
Jennifer Dressman
i
;
Simone Hansmann
i
;
Edmund Kostewicz
i
;
Handan He
j
;
Tycho Heimbach
j
;
Fan Wu
j
;
Carolin Hoft
k
;
Yan Pang
k
;
Michael B. Bolger
l
;
Eva Huehn
l
;
Viera Lukacova
l
;
James M. Mullin
l
;
Ke X. Szeto
l
;
Chester Costales
m
;
Jian Lin
m
;
Mark McAllister
n
;
Sweta Modi
m
;
Charles Rotter
m
;
Manthena Varma
n
;
Mei Wong
n
;
Amitava Mitra
o
;
Jan Bevernage
p
;
Jeike Biewenga
p
;
Achiel Van Peer
p
;
Richard Lloyd
q
关键词:
AFE
;
Average Fold Error
;
AAFE
;
Absolute Average Fold Error
;
API
;
Active pharmaceutical ingredient
;
AUC
;
Area under the curve
;
BCS
;
Biopharmaceutics classification system
;
BE
;
Bioequivalence
;
BP
;
Blood-to-plasma ratio
;
CCC
;
Concordance Correlation Coefficient
;
CL
;
Clearance
;
CL/F
;
Apparent clearance
;
Cmax
;
Maximum concentration
;
Do
;
Dose number
;
fa
;
Fraction absorbed
;
FE
;
Fold Error
;
FIM
;
First In Man
;
Foral
;
Absolute oral bioavailability
;
Frel
;
Relative bioavailability
;
fup
;
fraction unbound in
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
3.
Ecosystem uptake and transfer of Sellafield-derived radiocarbon (
14
C). Part 1. The Irish Sea
作者:
Graham K.P. Muir
a
;
b
;
graham.muir@glasgow.ac.uk
;
Kieran M. Tierney
a
;
b
;
Gordon T. Cook
a
;
Gillian MacKinnon
a
;
John A. Howe
b
;
Johanna
J. Heymans
b
;
David J. Hughes
b
;
Sheng Xu
a
关键词:
Sellafield
;
Radiocarbon (14C)
;
Irish Sea
;
Biotic uptake
;
Seawater
;
Sediment
刊名:Marine Pollution Bulletin
出版年:2017
4.
Evidence-Based and Personalized Medicine. It’s [AND] not [OR]
作者:
Sahar Mokhles
;
PhD
a
;
Johanna
JM Takkenberg
;
MD
;
PhD
a
;
Tom Treasure
;
MD
;
MS
b
;
tom.treasure@gmail.com
关键词:
CONSORT
;
Consolidated Standards of Reporting Trials
;
EBM
;
evidence-based medicine
;
GRADE
;
Grading of Recommendations Assessment
;
Development and Evaluation
;
IRLM
;
International Registry of Lung Metastases
;
MOOSE
;
Meta-analysis of Observational Studies in Epidemiology
;
RCT
;
randomized controlled trial
;
PICO
;
P = patients
;
population
;
or participants
;
I = intervention
;
C = control or comparator
;
O = outcome
;
PRISMA
;
Preferred Reporting Items for Systematic Reviews and Meta-Analyses
刊名:The Annals of Thoracic Surgery
出版年:2017
5.
Humic dissolved organic carbon drives oxidative stress and severe fitness impairments in Daphnia
作者:
Manja Saebelfeld
a
;
b
;
1
;
msaebelfeld@gmail.com
;
Laë
;
titia Minguez
c
;
1
;
laetitia-minguez@hotmail.fr
;
Johanna
Griebel
a
;
Mark O. Gessner
c
;
d
;
Justyna Wolinska
a
;
b
关键词:
Zooplankton
;
DOC
;
Stress response
;
Life history traits
;
Environmental change
;
Browning
刊名:Aquatic Toxicology
出版年:2017
6.
Mechanism of antiproliferative action of a new d-secoestrone-triazole derivative in cervical cancer cells and its effect on cancer cell motility
作者:
Noé
;
mi Bó
;
zsity
a
;
Rená
;
ta Minorics
a
;
Johanna
Szabó
;
b
;
Erzsé
;
bet Mernyá
;
k
b
;
Gyula Schneider
b
;
Já
;
nos Wö
;
lfling
b
;
Hui-Chun Wang
c
;
Chin-Chung Wu
c
;
Imre Ocsovszki
d
;
Istvá
;
n Zupkó
;
a
;
zupko@pharm.u-szeged.hu
关键词:
d-SET
;
d-secoestrone-triazole
;
HPV
;
Human Papilloma Virus
;
2-ME
;
2-methoxyestradiol
;
PAC
;
paclitaxel
;
Bid
;
BH3 interacting-domain death agonist
;
Bcl-2
;
B-cell CLL/lymphoma 2
;
FADD
;
Fas-Associated protein with Death Domain
;
DISC
;
death-inducing signalling complex
刊名:The Journal of Steroid Biochemistry and Molecular Biology
出版年:2017
7.
Pharmacy customers’ experiences with the national online service for viewing electronic prescriptions in Finland
作者:
Elina Lä
;
msä
;
a
;
elina.lamsa@uef.fi
;
Johanna
Timonen
a
;
johanna
.timonen@uef.fi
;
Pekka Mä
;
ntyselkä
;
b
;
c
;
pekka.mantyselka@uef.fi
;
Riitta Ahonen
a
;
riitta.ahonen@uef.fi
关键词:
Patient access to records
;
Electronic prescription
;
Pharmacy customer
;
Survey
刊名:International Journal of Medical Informatics
出版年:2017
8.
Immunogenicity of tocilizumab in patients with rheumatoid arthritis
作者:
Johanna
Sigaux
a
;
b
;
c
;
1
;
Moustafa Hamze
d
;
1
;
Claire Daien
e
;
f
;
Jacques Morel
e
;
f
;
Roman Krzysiek
g
;
h
;
i
;
Marc Pallardy
j
;
Bernard Maillere
d
;
Xavier Mariette
a
;
b
;
c
;
2
;
Corinne Miceli-Richard
a
;
b
;
c
;
2
;
corinne.miceli@aphp.fr
关键词:
Immunogenicity
;
Tocilizumab
;
Rheumatoid arthritis
刊名:Joint Bone Spine
出版年:2017
9.
Minimal Clinically Important Difference of Berg Balance Scale in People With Multiple Sclerosis
作者:
Elisa Gervasoni
;
PT
;
MSc
;
Johanna
Jonsdottir
;
PhD
;
Angelo Montesano
;
MD
;
Davide Cattaneo
;
PhD
;
dcattaneo@dongnocchi.it
关键词:
Multiple sclerosis
;
Patient outcome assessment
;
Postural balance
;
Rehabilitation
刊名:Archives of Physical Medicine and Rehabilitation
出版年:2017
10.
Usability problems do not heal by themselves: National survey on physicians’ experiences with EHRs in Finland
作者:
Johanna
Kaipio
a
;
Johanna
.Kaipio@aalto.fi
;
Tinja Lä
;
ä
;
veri
b
;
Hannele Hyppö
;
nen
c
;
Suvi Vainiomä
;
ki
d
;
Jarmo Reponen
e
;
f
;
Andre Kushniruk
g
;
Elizabeth Borycki
g
;
Jukka Vä
;
nskä
;
h
关键词:
Usability
;
User experience
;
Physician
;
Questionnaire
;
Electronic health record system
;
Health information system
;
National survey
刊名:International Journal of Medical Informatics
出版年:2017
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