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知网期刊论文(568)
在“
Elsevier电子期刊
”中,
命中:
657
条,耗时:小于0.01 秒
在所有数据库中总计命中:
964
条
1.
Design and synthesis of 4,5,6,7‐tetrahydro‐1H‐1,2‐diazepin‐7‐one derivatives as a new series of Phosphodiesterase 4 (
PDE4
) inhibitors
作者:
Sara Guariento
a
;
Anna Karawajczyk
b
;
James A. Bull
b
;
Gessica Marchini
c
;
Martyna Bielska
b
;
Xenia Iwanowa
b
;
Olga Bruno
a
;
Paola Fossa
a
;
Fabrizio Giordanetto
b
;
fabrizio.giordanetto@deshawresearch.com
关键词:
Phosphodiesterase 4
;
PDE4
inhibitors
;
Diazepinone derivatives
;
Compound library
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
2.
Modulation of signaling through GPCR-cAMP-PKA pathways by
PDE4
depends on stimulus intensity: Possible implications for the pathogenesis of acrodysostosis without hormone resistance
作者:
Emmanuelle Motte
a
;
Catherine Le Stunff
a
;
Claire Briet
a
;
Nicolas Dumaz
b
;
Caroline Silve
a
;
c
;
d
;
caroline.silve@inserm.fr
关键词:
cAMP
;
PDE4
D
;
Acrodysostosis
;
BRET
;
Inhibition
;
Hormonal response
刊名:Molecular and Cellular Endocrinology
出版年:2017
3.
Hangover Links Nuclear RNA Signaling to cAMP Regulation via the Phosphodiesterase 4d Ortholog dunce
作者:
Manuela Ruppert
1
;
4
;
Mirjam Franz
2
;
4
;
Anastasios Saratsis
2
;
Laura Velo Escarcena
1
;
Oliver Hendrich
1
;
5
;
Li Ming Gooi
1
;
6
;
Isabell Schwenkert
2
;
Ansgar Klebes
3
;
Henrike Scholz
1
;
2
;
7
;
henrike.scholz@uni-koeln.de
关键词:
hangover
;
dunce
;
Dunce isoforms
;
PDE4
d
;
cellular stress
;
alcohol tolerance
;
Drosophila melanogaster
刊名:Cell Reports
出版年:2017
4.
RACK1 and β-arrestin2 attenuate dimerization of
PDE4
cAMP phosphodiesterase PDE4D5
作者:
Graeme B. Bolger
;
gbbolger@uab.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
PDE4
;
PKA
;
ERK1/2
;
MK2
;
β2-adrenergic receptors
;
Acrodysostosis
刊名:Cellular Signalling
出版年:2016
5.
PDE4
D phosphorylation: A coincidence detector integrating multiple signaling pathways
作者:
Delphine Mika
1
;
Marco Conti
关键词:
Phosphodiesterase
;
PDE4
D
;
Phosphorylation
;
Posttranslational modification
刊名:Cellular Signalling
出版年:2016
6.
1,2,3-Triazole-nimesulide hybrid: Their design, synthesis and evaluation as potential anticancer agents
作者:
Jyoti Mareddy
a
;
b
;
N. Suresh
b
;
C. Ganesh Kumar
c
;
Ravikumar Kapavarapu
d
;
A. Jayasree
b
;
Sarbani Pal
a
;
sarbani277@yahoo.com
关键词:
Nimesulide
;
1
2 ;
3-Triazole
;
Azide
;
Alkyne
;
Anticancer activity
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
7.
Regulation of Cardiac Pacemaker Activity by
PDE4
Isoforms
刊名:Biophysical Journal
出版年:2017
8.
Mesembrine alkaloids: Review of their occurrence, chemistry, and pharmacology
作者:
John L. Krstenansky
John_Krstenansky@kgi.edu
关键词:
Mesembrine (PubChem CID 394162)
;
Mesembrenone (Pubchem CID 216272)
;
Mesembrinol (PubChem CID 442112)
;
Sceletenone (PubChem CID 102239734)
刊名:Journal of Ethnopharmacology
出版年:2017
9.
Cardiac Gene Therapy with Phosphodiesterases PDE2A and
PDE4
B Ameliorates Cardiac Function in a Mouse Model of Heart Failure Induced by Chronic Isoproterenol Infusion
刊名:Biophysical Journal
出版年:2017
10.
Synthesis and bioactivity of pyrazole and triazole derivatives as potential
PDE4
inhibitors
作者:
Ya-Sheng Li
a
;
&dagger
;
;
Hao Tian
a
;
&dagger
;
;
Dong-Sheng Zhao
b
;
&dagger
;
;
De-Kun Hu
a
;
Xing-Yu Liu
a
;
Hong-Wei Jin
c
;
Gao-Peng Song
d
;
vinsin1021@126.com" class="auth_mail" title="E-mail the corresponding author
;
Zi-Ning Cui
a
;
ziningcui@scau.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
Synthesis
;
5-Phenyl-2-furan
;
Pyrazole and triazole derivatives
;
PDE4
inhibitor
;
Molecular simulation
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
1
2
3
4
5
6
7
8
9
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